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From FDA reports: drug interactions between Amitriptyline Hcl, Senna Liquid Extract, Comtan for a Female patient aged 71

This is a personalized study for a 71 year old female patient. The study is created by eHealthMe based on reports of 51 people who take the same drugs and have drug interactionsfrom FDA.

On Sep, 2, 2014: 51 people who reported to have interactions when taking Amitriptyline Hcl, Senna Liquid Extract, Comtan are studied

Trend of Amitriptyline Hcl, Senna Liquid Extract, Comtan's drug interactions, side effects, and effectiveness reports (3742127)

Information of the patient in this study:

Age: 71

Gender: female

Conditions: Depression, Drug Effect Decreased

Drugs taking:
- Amitriptyline Hcl
- Senna Liquid Extract
- Comtan: used for 1 - 2 years

Drug interactions have: Tremor, Serotonin Syndrome, Hyperreflexia, Flushing, Dyskinesia, Chills, Anxiety

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 71 (±5):

InteractionNumber of reports
Tremor (trembling or shaking movements in one or more parts of your body)4 (21.05%)
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)2 (10.53%)
Hyperreflexia (overactive or over responsive reflexes)2 (10.53%)
Flushing (the warm, red condition of human skin)6 (31.58%)
Dyskinesia (abnormality or impairment of voluntary movement)2 (10.53%)
Chills (felling of cold)3 (15.79%)
Anxiety3 (15.79%)

Most common interactions experienced by females aged 71 (±5) in the use of Amitriptyline Hcl, Senna Liquid Extract, Comtan:

InteractionNumber of reports
Lethargy (tiredness)16
Drug Interaction14
Fatigue (feeling of tiredness)12
Drug Dispensing Error10
Photophobia (extreme sensitivity to light)10
Unresponsive To Stimuli10
Confusional State10
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones)8
Sedation8
Drug Ineffective8

Most common interactions experienced by females aged 71 (±5) in long term use of Amitriptyline Hcl, Senna Liquid Extract, Comtan:

InteractionNumber of reports
Anxiety1
Flushing (the warm, red condition of human skin)1
Tremor (trembling or shaking movements in one or more parts of your body)1
Dyskinesia (abnormality or impairment of voluntary movement)1
Chills (felling of cold)1
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)1
Hyperreflexia (overactive or over responsive reflexes)1

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Tremor (trembling or shaking movements in one or more parts of your body)6 (11.76%)
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)2 (3.92%)
Hyperreflexia (overactive or over responsive reflexes)2 (3.92%)
Flushing (the warm, red condition of human skin)9 (17.65%)
Dyskinesia (abnormality or impairment of voluntary movement)4 (7.84%)
Chills (felling of cold)3 (5.88%)
Anxiety22 (43.14%)

Most common interactions experienced by people in the use of Amitriptyline Hcl, Senna Liquid Extract, Comtan:

InteractionNumber of reports
Pathological Gambling28
Depression28
Anxiety22
Obsessive-compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)20
Drug Interaction14
Suicidal Ideation12
Abnormal Behaviour11
Drug Dispensing Error10
Confusional State10
Condition Aggravated (worse condition)10

Most common interactions experienced by people in long term use of Amitriptyline Hcl, Senna Liquid Extract, Comtan:

InteractionNumber of reports
Anxiety1
Flushing (the warm, red condition of human skin)1
Tremor (trembling or shaking movements in one or more parts of your body)1
Dyskinesia (abnormality or impairment of voluntary movement)1
Chills (felling of cold)1
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)1
Hyperreflexia (overactive or over responsive reflexes)1

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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