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Eylea vs Lucentis vs Avastin, a side effect and effectiveness comparison for a female patient aged 84

This is personalized comparison of Eylea vs Lucentis vs Avastin for a female aged 84. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Eylea (latest outcomes from 166 users) has active ingredients of aflibercept. It is often used in macular degeneration.

Lucentis (latest outcomes from 9,594 users) has active ingredients of ranibizumab. It is often used in macular degeneration.

Avastin (latest outcomes from 24,094 users) has active ingredients of bevacizumab. It is often used in macular degeneration.

What are the symptoms

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis) has been reported by people with birth control, pain, multiple myeloma, premenstrual syndrome, high blood pressure.(latest reports from Deep vein thrombosis 42,666 patients)

Abdominal pain has been reported by people with birth control, crohn's disease, high blood pressure, pain, depression.(latest reports from Abdominal pain 106,123 patients)

Diarrhoea has been reported by people with high blood pressure, pain, rheumatoid arthritis, osteoporosis, depression.(latest reports from Diarrhoea 169,442 patients)

Death (latest reports from Death 183,730 patients)

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle) has been reported by people with diabetes, arthritis, pain, high blood pressure, multiple sclerosis.(latest reports from Myocardial infarction 130,932 patients)

Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)) has been reported by people with high blood pressure, diabetes, osteoporosis, arthritis, pain.(latest reports from Transient ischaemic attack 23,187 patients)

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture) has been reported by people with diabetes, arthritis, high blood pressure, pain, multiple sclerosis.(latest reports from Cerebrovascular accident 103,447 patients)

On Oct, 13, 2014: 1,462 female patients aged 83 who take the same drugs are studied in Eylea vs Lucentis vs Avastin

Information of patient in study:

GenderAgeReason for the drug
Female83Age-related macular degeneration (ARMD or AMD)

Drugs to compare:

DrugIngredientsCompany
Eylea afliberceptnot specified
Lucentis ranibizumabnot specified
Avastin bevacizumabnot specified

eHealthMe real world results:

For females aged 83 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

EyleaLucentisAvastin
Deep Vein Thrombosisn/a1.00%2.13%
Abdominal Painn/a0.25%0.91%
Diarrhoean/a0.75%7.93%
Deathn/a10.95%5.18%
Myocardial Infarctionn/a6.47%3.05%
Transient Ischaemic Attackn/a4.73%2.74%
Cerebrovascular Accidentn/a22.64%4.88%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
EyleaLucentisAvastin
Visual Acuity Reduced (reduced clearness of vision)Dehydration (dryness resulting from the removal of water)
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Diarrhoea
DeathDetachment Of Retinal Pigment Epithelium
Retinal Haemorrhage (bleeding from retina)Nausea (feeling of having an urge to vomit)
Retinal Pigment Epithelial Tear (pigment epithelial tear of retina)Intraocular Pressure Increased
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Febrile Neutropenia (fever with reduced white blood cells)
Eye PainAsthenia (weakness)
Malaise (a feeling of general discomfort or uneasiness)Endophthalmitis (inflammation of the internal coats of the eye)
FallVisual Acuity Reduced (reduced clearness of vision)
Blood Pressure IncreasedCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
EyleaLucentisAvastin
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Cerebral Disorder (brain disease)
Visual Acuity Reduced (reduced clearness of vision)Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Endophthalmitis (inflammation of the internal coats of the eye)Oral Pain
Blood Pressure IncreasedPulmonary Embolism (blockage of the main artery of the lung)
Eye DisorderSwelling
Pain In ExtremityOsteonecrosis (death of bone)
Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain)Bone Disorder
Eye SwellingErythema (redness of the skin)
Intraocular Pressure IncreasedAnaemia (lack of blood)
Dry MouthDeep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Eylea0.000.000.000.000.00
Lucentis0.00%50.00%0.00%50.00%0.00%
Avastin0.00%50.00%25.00%25.00%0.00%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Eylea (aflibercept) is often used to treat macular degeneration. Lucentis (ranibizumab) is often used to treat macular degeneration. Avastin (bevacizumab) is often used to treat macular degeneration. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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