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Home > Health tools > Drug comparison > Benadryl vs Loratadine

Benadryl vs Loratadine, a side effect and effectiveness comparison for a female patient aged 56

This is personalized comparison of Benadryl vs Loratadine for a female aged 56. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Loratadine (latest outcomes from 10,971 users) has active ingredients of loratadine. It is often used in allergies.

On Oct, 31, 2014: 7,129 female patients aged 53 who take the same drugs are studied in Benadryl vs Loratadine

Information of patient in study:

GenderAgeReason for the drug
Female53Bee sting

Drugs to compare:

DrugIngredientsCompany
Benadryl diphenhydramine hydrochlorideMcneil Cons
Loratadine loratadineSandoz

eHealthMe real world results:

For females aged 53 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Benadryl (Mcneil Cons)Loratadine (Sandoz)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Pyrexia (fever)Chest Pain
Pruritus (severe itching of the skin)Dyspnoea (difficult or laboured respiration)
PainDepression
VomitingHeadache (pain in head)
AnxietyDrug Ineffective
Headache (pain in head)Anxiety
DizzinessPyrexia (fever)
Chest PainPain

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Benadryl (Mcneil Cons)Loratadine (Sandoz)
Ringing In The Ears (a ringing in the ears)Depression
Flushing (the warm, red condition of human skin)High Blood Cholesterol
Insomnia Exacerbated (sleeplessness)Failed Back Surgery Syndrome (persistent pain following back surgery)
Dermatitis Lichen Planus-like (well-defined area of a purple-coloured itchy rash)Cough
Bone LossHerniated Intervertebral Disk
Low Blood Pressure (abnormally low blood pressure)Heart Injury
DizzinessSeasonal Allergy (allergic condition due to certain season)
High Blood Sugar (high blood sugar)Fatigue (feeling of tiredness)
Face PainDysphagia (condition in which swallowing is difficult or painful)
Skin Burning SensationOedema Peripheral (superficial swelling)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Benadryl0.81%21.86%38.87%31.58%6.88%
Loratadine1.59%22.75%39.68%25.40%10.58%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Loratadine (loratadine) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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