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Cosopt vs Combigan, a side effect and effectiveness comparison for a male patient aged 65

This is personalized comparison of Cosopt vs Combigan for a male aged 65. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Cosopt (latest outcomes from 2,931 users) has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma.

Combigan (latest outcomes from 1,281 users) has active ingredients of brimonidine tartrate; timolol maleate. It is often used in glaucoma.

On May, 15, 2014: 241 male patients aged 62 who take the same drugs are studied in Cosopt vs Combigan

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Cosopt dorzolamide hydrochloride; timolol maleateMerck
Combigan brimonidine tartrate; timolol maleatenot specified

eHealthMe real world results:

For males aged 62 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Cosopt (Merck)Combigan
Nausea (feeling of having an urge to vomit)Ocular Hyperaemia (an abnormally large amount of blood in eye)
Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)Small Intestinal Obstruction (blockage in small intestine)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Eye Irritation
Intraocular Pressure IncreasedPigmentary Glaucoma (affliction of the eye that can lead to a form of glaucoma)
VomitingCataract (clouding of the lens inside the eye)
HypersensitivityEye Disorder
Syncope (loss of consciousness with an inability to maintain postural tone)Intraocular Pressure Increased
Drug IneffectiveVisual Impairment
Hypokalaemia (low potassium)Condition Aggravated
Renal Failure (kidney dysfunction)Blepharitis (chronic inflammation of the eyelid)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Cosopt (Merck)Combigan
Intraocular Pressure IncreasedNosebleed (bleeding from nose)
Hypoaesthesia Facial (reduced sense of touch or sensation on face)
Hypoaesthesia (reduced sense of touch or sensation)
Gait Disturbance
Drug Ineffective
Vision Blurred
Halo Vision (rainbow vision)
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Drug Hypersensitivity

Drug effectiveness:

not at allsomewhatmoderatehighvery high

Comments from or about the patient:

What is the basic diffreance between Cosopt and Combigan

How to use the study:
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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Cosopt (dorzolamide hydrochloride; timolol maleate) is often used to treat glaucoma. Combigan (brimonidine tartrate; timolol maleate) is often used to treat glaucoma. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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- Combigan side effects
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Related conditions

- Glaucoma



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