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Related topic: Acid Reflux, Aciphex, Anxiety, Cymbalta, Dry Eyes, Dry Mouth, Heartburn, Horizant, Ibuprofen, Insomnia, Muscle Weakness, Neck Pain, Pain, Pain - joints, Shortness of breath, Tramadol, Trazodone Hydrochloride, Vertigo

What could cause Insomnia, Neck Pain, Dry Mouth, Dry Eyes, Vertigo, Acid Reflux, Shortness of breath, Muscle Weakness, Pain - joints for a 28-year old woman?

This is a study of Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant for a 28 year old female patient who has Pain, Insomnia, Anxiety, Heartburn. The study is created by eHealthMe based on 4 female patients aged 28 (±5) who take the drugs from FDA and social media.

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On Mar, 9, 2014: 4 females aged 27 (±5) who reported to have interactions when taking Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant are studied

Trend of Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant's drug interactions, side effects and effectiveness reports (9737467)

Information of the patient in this study:

Age: 27

Gender: female

Conditions: Pain, Insomnia, Anxiety, Heartburn

Drugs taking:
- Ibuprofen (ibuprofen): used for 6 - 12 months
- Tramadol (tramadol hydrochloride): used for 1 - 6 months
- Trazodone Hydrochloride (trazodone hydrochloride): used for 1 - 6 months
- Cymbalta (duloxetine hydrochloride): used for 1 - 6 months
- Aciphex (rabeprazole sodium): used for 1 - 6 months
- Horizant (gabapentin enacarbil): used for 1 - 6 months

Drug interactions have: moderate insomnia, moderate neck pain, moderate dry mouth, least dry eyes, moderate vertigo, moderate acid reflux, moderate shortness of breath, moderate muscle weakness, severe pain - joints

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
among females aged 27 (±5) who take the drugs
Insomnia (sleeplessness)1 (25.00%)
Neck Pain1 (25.00%)
Dry Mouth1 (25.00%)
Dry Eyes (lack of adequate tears)1 (25.00%)
Vertigo4 (100.00%)
Acid Reflux (stomach acids rise up)2 (50.00%)
Shortness Of Breath2 (50.00%)
Muscle Weakness (a lack of muscle strength)2 (50.00%)
Pain - Joints2 (50.00%)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

SymptomNumber of reports
among females aged 27 (±5) who have the condition, regardless of which drug is taken
Insomnia in Pain123 (2.19%)
Insomnia in Insomnia0 (0.00%)
Insomnia in Anxiety268 (4.19%)
Insomnia in Heartburn6 (0.78%)
Neck Pain in Pain53 (0.94%)
Neck Pain in Insomnia23 (0.89%)
Neck Pain in Anxiety42 (0.66%)
Neck Pain in Heartburn4 (0.52%)
Dry Mouth in Pain10 (0.18%)
Dry Mouth in Insomnia16 (0.62%)
Dry Mouth in Anxiety41 (0.64%)
Dry Mouth in Heartburn7 (0.91%)
Dry Eyes in Pain1 (0.02%)
Dry Eyes in Insomnia6 (0.23%)
Dry Eyes in Anxiety9 (0.14%)
Dry Eyes in Heartburn2 (0.26%)
Vertigo in Pain209 (3.72%)
Vertigo in Insomnia79 (3.07%)
Vertigo in Anxiety357 (5.58%)
Vertigo in Heartburn16 (2.08%)
Acid Reflux in Pain13 (0.23%)
Acid Reflux in Insomnia5 (0.19%)
Acid Reflux in Anxiety11 (0.17%)
Acid Reflux in Heartburn0 (0.00%)
Shortness Of Breath in Pain241 (4.29%)
Shortness Of Breath in Insomnia71 (2.76%)
Shortness Of Breath in Anxiety178 (2.78%)
Shortness Of Breath in Heartburn3 (0.39%)
Muscle Weakness in Pain129 (2.30%)
Muscle Weakness in Insomnia51 (1.98%)
Muscle Weakness in Anxiety120 (1.88%)
Muscle Weakness in Heartburn2 (0.26%)
Pain - Joints in Pain96 (1.71%)
Pain - Joints in Insomnia51 (1.98%)
Pain - Joints in Anxiety76 (1.19%)
Pain - Joints in Heartburn3 (0.39%)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effectNumber of reports
among females aged 27 (±5) who take the drug
Insomnia in Ibuprofen110 (2.22%)
Insomnia in Tramadol74 (3.83%)
Insomnia in Trazodone Hydrochloride12 (2.00%)
Insomnia in Cymbalta124 (4.64%)
Insomnia in Aciphex7 (1.95%)
Insomnia in Horizant1 (20.00%)
Neck Pain in Ibuprofen40 (0.81%)
Neck Pain in Tramadol39 (2.02%)
Neck Pain in Trazodone Hydrochloride4 (0.67%)
Neck Pain in Cymbalta11 (0.41%)
Neck Pain in Aciphex5 (1.39%)
Neck Pain in Horizant1 (20.00%)
Dry Mouth in Ibuprofen21 (0.42%)
Dry Mouth in Tramadol12 (0.62%)
Dry Mouth in Trazodone Hydrochloride5 (0.83%)
Dry Mouth in Cymbalta19 (0.71%)
Dry Mouth in Aciphex4 (1.11%)
Dry Mouth in Horizant1 (20.00%)
Dry Eyes in Ibuprofen8 (0.16%)
Dry Eyes in Tramadol3 (0.16%)
Dry Eyes in Trazodone Hydrochloride1 (0.17%)
Dry Eyes in Cymbalta5 (0.19%)
Dry Eyes in Aciphex1 (0.28%)
Dry Eyes in Horizant1 (20.00%)
Vertigo in Ibuprofen227 (4.59%)
Vertigo in Tramadol144 (7.45%)
Vertigo in Trazodone Hydrochloride14 (2.33%)
Vertigo in Cymbalta191 (7.15%)
Vertigo in Aciphex27 (7.52%)
Vertigo in Horizant3 (60.00%)
Acid Reflux in Ibuprofen6 (0.12%)
Acid Reflux in Tramadol4 (0.21%)
Acid Reflux in Trazodone Hydrochloride2 (0.33%)
Acid Reflux in Cymbalta3 (0.11%)
Acid Reflux in Aciphex1 (0.28%)
Acid Reflux in Horizant1 (20.00%)
Shortness Of Breath in Ibuprofen336 (6.79%)
Shortness Of Breath in Tramadol119 (6.16%)
Shortness Of Breath in Trazodone Hydrochloride12 (2.00%)
Shortness Of Breath in Cymbalta70 (2.62%)
Shortness Of Breath in Aciphex24 (6.69%)
Shortness Of Breath in Horizant1 (20.00%)
Muscle Weakness in Ibuprofen156 (3.15%)
Muscle Weakness in Tramadol97 (5.02%)
Muscle Weakness in Trazodone Hydrochloride9 (1.50%)
Muscle Weakness in Cymbalta73 (2.73%)
Muscle Weakness in Aciphex14 (3.90%)
Muscle Weakness in Horizant1 (20.00%)
Pain - Joints in Ibuprofen103 (2.08%)
Pain - Joints in Tramadol78 (4.04%)
Pain - Joints in Trazodone Hydrochloride3 (0.50%)
Pain - Joints in Cymbalta26 (0.97%)
Pain - Joints in Aciphex11 (3.06%)
Pain - Joints in Horizant1 (20.00%)

Most common interactions experienced by females aged 27 (±5) in the use of Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant:

InteractionNumber of reports
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)4
Type 2 Diabetes Mellitus4
Hyperglycaemia (high blood sugar)4
Blood Cholesterol Increased4
Dizziness4
Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright)3
Glycosuria (excretion of glucose into the urine)3
Tremor (trembling or shaking movements in one or more parts of your body)3
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)3
Dry Mouth1

Most common interactions experienced by females aged 27 (±5) in long term use of Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant:

None.

How effective are the drugs for females aged 27 (±5):

not at allsomewhatmoderatehighvery high
Ibuprofen0.00%100.00%0.00%0.00%0.00%
Tramadol0.000.000.000.000.00
Trazodone Hydrochloride0.000.000.000.000.00
Cymbalta0.000.000.000.000.00
Aciphex0.000.000.000.000.00
Horizant0.000.000.000.000.00

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (2 weeks ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

  • From this study (2 weeks ago):

  • I have been struggling with sinusitis for almost 2 years now and they can't stop the dripping my nose from running,down throat to chest, lots of plegm, and have been congested for over a year and half. Since then, have tried me on every sort of antihistimine, Loradine, Zyrtec, Certirizine, and fluticasone spray, which didn't stop running/congestion. Been to ER three times to get on antibiotics since also caused gum disease/gingivitis per Periodontus who states it's underlying medical not dental. Also started taking regular OTC sudafed for congestion, and occasional cough/congestion. Now allergist says my IgG Immoglobins are high and was told that since I have constant bacterial infections. Allergist believes running nose/congestion is from a fungus infection or vasomotor rhinitis and need culture. Am waiting to see ENT. Prior to this last 2 years, my sinus was always controlled and maybe every year to two years, an infection occurred and antibiotics quickly got rid of it, but not this time. I read infections could also cause liver enzymes to rise to and my past blood tests in 2008 shows only had a mild increase in SGPT ALT only. Prior use, I used pain pills, vicodin/codeine/darvocet/, but stay away from then now due to liver enzymes in ALT rising, and only use motrin, sleeping med., cymbalta and occasional fioricet. Had gall bladder infected and removed, and tests show fatty liver and slight kidney lesion, but not enough for them to do anything.

    Reply

    help on Apr, 9, 2014:

    F, 48, fibromylagia, chronic sinusitis, repeated infections, which believe long-term pain meds cause elevated liver enzymes, went off most, and now because of constant trying of allergy meds, and can't stop running nose, long term infections of bacteria and possibly fungus, so not sure what is causing elevated enzymes.

    Reply

  • From this study (3 weeks ago):

  • I gained weight rapidly and want to know if any of these medications or combination of any of them caused the weight gain.

    Reply

    Ronnie on Apr, 5, 2014:

    Hell yes they could cause weight gain! The progesterone alone could do it! Not to mention all the other meds...

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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