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What could cause Insomnia, Neck Pain, Dry Mouth, Dry Eyes, Vertigo, Acid Reflux, Shortness of breath, Muscle Weakness, Pain - joints for a 28-year old woman who takes Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant?





Summary: 4 female patients aged 28 (±5) who take the same drugs are studied.

This is a personalized study for a 28 year old female patient who has Pain, Insomnia, Anxiety, Heartburn. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 61,602 users)

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 41,511 users)

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 6,611 users)

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 49,275 users)

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. (latest outcomes from Aciphex 12,007 users)

Horizant has active ingredients of gabapentin enacarbil. It is often used in restless leg syndrome. (latest outcomes from Horizant 151 users)

What are the conditions

Pain can be treated by Hydrocodone Bitartrate And Acetaminophen, Vicodin, Percocet, Tramadol Hydrochloride, Ibuprofen, Oxycontin. (latest reports from Pain 291,941 patients)

Insomnia (sleeplessness) can be treated by Ambien, Trazodone Hydrochloride, Lunesta, Zolpidem Tartrate, Ambien Cr, Zopiclone. (latest reports from Insomnia 143,612 patients)

Anxiety can be treated by Xanax, Klonopin, Clonazepam, Lexapro, Ativan, Lorazepam. (latest reports from Anxiety 212,304 patients)

Heartburn (a condition in which stomach contents leak backward from the stomach into the oesophagus) can be treated by Omeprazole, Nexium, Prilosec, Prevacid, Protonix, Prilosec Otc. (latest reports from Heartburn 10,552 patients)

What are the symptoms

Insomnia has been reported by people with depression, quit smoking, high blood pressure, pain, stress and anxiety.(latest reports from Insomnia 135,811 patients)

Neck pain has been reported by people with osteoporosis, multiple sclerosis, pain, high blood pressure, rheumatoid arthritis.(latest reports from Neck pain 23,791 patients)

Dry mouth has been reported by people with high blood pressure, depression, chronic obstructive pulmonary disease, osteoporosis, high blood cholesterol.(latest reports from Dry mouth 30,429 patients)

Dry Eyes (lack of adequate tears) has been reported by people with high blood pressure, rheumatoid arthritis, osteoporosis, acne, depression.(latest reports from Dry Eyes 10,597 patients)

Vertigo has been reported by people with high blood pressure, depression, osteoporosis, multiple sclerosis, high blood cholesterol.(latest reports from Vertigo 162,939 patients)

Acid reflux (stomach acids rise up) has been reported by people with high blood pressure, depression, osteoporosis, pain, high blood cholesterol.(latest reports from Acid reflux 10,551 patients)

Shortness Of Breath has been reported by people with high blood pressure, asthma, rheumatoid arthritis, pain, chronic obstructive pulmonary disease.(latest reports from Shortness Of Breath 164,498 patients)

Muscle weakness (a lack of muscle strength) has been reported by people with multiple sclerosis, high blood pressure, high blood cholesterol, osteoporosis, pain.(latest reports from Muscle weakness 181,414 patients)

Pain - joints has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, high blood cholesterol, multiple sclerosis.(latest reports from Pain - joints 117,676 patients)

On Nov, 26, 2014: 4 females aged 27 (±5) who take Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant are studied

Ibuprofen, Tramadol, Trazodone Hydrochloride, Cymbalta, Aciphex, Horizant outcomes

Information of the patient in this study:

Age: 27

Gender: female

Conditions: Pain, Insomnia, Anxiety, Heartburn

Drugs taking:
- Ibuprofen (ibuprofen): used for 6 - 12 months
- Tramadol (tramadol hydrochloride): used for 1 - 6 months
- Trazodone Hydrochloride (trazodone hydrochloride): used for 1 - 6 months
- Cymbalta (duloxetine hydrochloride): used for 1 - 6 months
- Aciphex (rabeprazole sodium): used for 1 - 6 months
- Horizant (gabapentin enacarbil): used for 1 - 6 months

Drug interactions have: moderate insomnia, moderate neck pain, moderate dry mouth, least dry eyes, moderate vertigo, moderate acid reflux, moderate shortness of breath, moderate muscle weakness, severe pain - joints

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Insomnia (sleeplessness)2 (50.00% of females aged 27 (±5) who take the drugs)
Neck Pain2 (50.00% of females aged 27 (±5) who take the drugs)
Dry Mouth2 (50.00% of females aged 27 (±5) who take the drugs)
Dry Eyes (lack of adequate tears)2 (50.00% of females aged 27 (±5) who take the drugs)
Vertigo4 (100.00% of females aged 27 (±5) who take the drugs)
Acid Reflux (stomach acids rise up)2 (50.00% of females aged 27 (±5) who take the drugs)
Shortness Of Breath2 (50.00% of females aged 27 (±5) who take the drugs)
Muscle Weakness (a lack of muscle strength)2 (50.00% of females aged 27 (±5) who take the drugs)
Pain - Joints2 (50.00% of females aged 27 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Insomnia in Pain124 (2.19% of females aged 27 (±5) who have Pain)
Insomnia in Insomnia0 (0.00% of females aged 27 (±5) who have Insomnia)
Insomnia in Anxiety270 (4.16% of females aged 27 (±5) who have Anxiety)
Insomnia in Heartburn7 (0.85% of females aged 27 (±5) who have Heartburn)
Neck Pain in Pain54 (0.95% of females aged 27 (±5) who have Pain)
Neck Pain in Insomnia23 (0.87% of females aged 27 (±5) who have Insomnia)
Neck Pain in Anxiety42 (0.65% of females aged 27 (±5) who have Anxiety)
Neck Pain in Heartburn4 (0.49% of females aged 27 (±5) who have Heartburn)
Dry Mouth in Pain10 (0.18% of females aged 27 (±5) who have Pain)
Dry Mouth in Insomnia16 (0.61% of females aged 27 (±5) who have Insomnia)
Dry Mouth in Anxiety41 (0.63% of females aged 27 (±5) who have Anxiety)
Dry Mouth in Heartburn7 (0.85% of females aged 27 (±5) who have Heartburn)
Dry Eyes in Pain1 (0.02% of females aged 27 (±5) who have Pain)
Dry Eyes in Insomnia6 (0.23% of females aged 27 (±5) who have Insomnia)
Dry Eyes in Anxiety9 (0.14% of females aged 27 (±5) who have Anxiety)
Dry Eyes in Heartburn2 (0.24% of females aged 27 (±5) who have Heartburn)
Vertigo in Pain211 (3.73% of females aged 27 (±5) who have Pain)
Vertigo in Insomnia81 (3.08% of females aged 27 (±5) who have Insomnia)
Vertigo in Anxiety362 (5.58% of females aged 27 (±5) who have Anxiety)
Vertigo in Heartburn17 (2.07% of females aged 27 (±5) who have Heartburn)
Acid Reflux in Pain13 (0.23% of females aged 27 (±5) who have Pain)
Acid Reflux in Insomnia5 (0.19% of females aged 27 (±5) who have Insomnia)
Acid Reflux in Anxiety12 (0.18% of females aged 27 (±5) who have Anxiety)
Acid Reflux in Heartburn0 (0.00% of females aged 27 (±5) who have Heartburn)
Shortness Of Breath in Pain242 (4.27% of females aged 27 (±5) who have Pain)
Shortness Of Breath in Insomnia75 (2.85% of females aged 27 (±5) who have Insomnia)
Shortness Of Breath in Anxiety178 (2.74% of females aged 27 (±5) who have Anxiety)
Shortness Of Breath in Heartburn4 (0.49% of females aged 27 (±5) who have Heartburn)
Muscle Weakness in Pain129 (2.28% of females aged 27 (±5) who have Pain)
Muscle Weakness in Insomnia53 (2.01% of females aged 27 (±5) who have Insomnia)
Muscle Weakness in Anxiety121 (1.86% of females aged 27 (±5) who have Anxiety)
Muscle Weakness in Heartburn5 (0.61% of females aged 27 (±5) who have Heartburn)
Pain - Joints in Pain97 (1.71% of females aged 27 (±5) who have Pain)
Pain - Joints in Insomnia51 (1.94% of females aged 27 (±5) who have Insomnia)
Pain - Joints in Anxiety77 (1.19% of females aged 27 (±5) who have Anxiety)
Pain - Joints in Heartburn4 (0.49% of females aged 27 (±5) who have Heartburn)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Insomnia in Ibuprofen110 (2.21% of females aged 27 (±5) who take Ibuprofen)
Insomnia in Tramadol76 (3.85% of females aged 27 (±5) who take Tramadol)
Insomnia in Trazodone Hydrochloride14 (2.24% of females aged 27 (±5) who take Trazodone hydrochloride)
Insomnia in Cymbalta125 (4.62% of females aged 27 (±5) who take Cymbalta)
Insomnia in Aciphex7 (1.95% of females aged 27 (±5) who take Aciphex)
Insomnia in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Neck Pain in Ibuprofen40 (0.80% of females aged 27 (±5) who take Ibuprofen)
Neck Pain in Tramadol39 (1.97% of females aged 27 (±5) who take Tramadol)
Neck Pain in Trazodone Hydrochloride4 (0.64% of females aged 27 (±5) who take Trazodone hydrochloride)
Neck Pain in Cymbalta12 (0.44% of females aged 27 (±5) who take Cymbalta)
Neck Pain in Aciphex5 (1.39% of females aged 27 (±5) who take Aciphex)
Neck Pain in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Dry Mouth in Ibuprofen21 (0.42% of females aged 27 (±5) who take Ibuprofen)
Dry Mouth in Tramadol12 (0.61% of females aged 27 (±5) who take Tramadol)
Dry Mouth in Trazodone Hydrochloride5 (0.80% of females aged 27 (±5) who take Trazodone hydrochloride)
Dry Mouth in Cymbalta19 (0.70% of females aged 27 (±5) who take Cymbalta)
Dry Mouth in Aciphex4 (1.11% of females aged 27 (±5) who take Aciphex)
Dry Mouth in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Dry Eyes in Ibuprofen8 (0.16% of females aged 27 (±5) who take Ibuprofen)
Dry Eyes in Tramadol3 (0.15% of females aged 27 (±5) who take Tramadol)
Dry Eyes in Trazodone Hydrochloride1 (0.16% of females aged 27 (±5) who take Trazodone hydrochloride)
Dry Eyes in Cymbalta5 (0.18% of females aged 27 (±5) who take Cymbalta)
Dry Eyes in Aciphex1 (0.28% of females aged 27 (±5) who take Aciphex)
Dry Eyes in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Vertigo in Ibuprofen227 (4.57% of females aged 27 (±5) who take Ibuprofen)
Vertigo in Tramadol144 (7.29% of females aged 27 (±5) who take Tramadol)
Vertigo in Trazodone Hydrochloride14 (2.24% of females aged 27 (±5) who take Trazodone hydrochloride)
Vertigo in Cymbalta191 (7.06% of females aged 27 (±5) who take Cymbalta)
Vertigo in Aciphex27 (7.52% of females aged 27 (±5) who take Aciphex)
Vertigo in Horizant3 (50.00% of females aged 27 (±5) who take Horizant)
Acid Reflux in Ibuprofen6 (0.12% of females aged 27 (±5) who take Ibuprofen)
Acid Reflux in Tramadol4 (0.20% of females aged 27 (±5) who take Tramadol)
Acid Reflux in Trazodone Hydrochloride2 (0.32% of females aged 27 (±5) who take Trazodone hydrochloride)
Acid Reflux in Cymbalta4 (0.15% of females aged 27 (±5) who take Cymbalta)
Acid Reflux in Aciphex1 (0.28% of females aged 27 (±5) who take Aciphex)
Acid Reflux in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Shortness Of Breath in Ibuprofen337 (6.78% of females aged 27 (±5) who take Ibuprofen)
Shortness Of Breath in Tramadol119 (6.03% of females aged 27 (±5) who take Tramadol)
Shortness Of Breath in Trazodone Hydrochloride13 (2.08% of females aged 27 (±5) who take Trazodone hydrochloride)
Shortness Of Breath in Cymbalta70 (2.59% of females aged 27 (±5) who take Cymbalta)
Shortness Of Breath in Aciphex24 (6.69% of females aged 27 (±5) who take Aciphex)
Shortness Of Breath in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Muscle Weakness in Ibuprofen156 (3.14% of females aged 27 (±5) who take Ibuprofen)
Muscle Weakness in Tramadol97 (4.91% of females aged 27 (±5) who take Tramadol)
Muscle Weakness in Trazodone Hydrochloride9 (1.44% of females aged 27 (±5) who take Trazodone hydrochloride)
Muscle Weakness in Cymbalta74 (2.73% of females aged 27 (±5) who take Cymbalta)
Muscle Weakness in Aciphex14 (3.90% of females aged 27 (±5) who take Aciphex)
Muscle Weakness in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)
Pain - Joints in Ibuprofen103 (2.07% of females aged 27 (±5) who take Ibuprofen)
Pain - Joints in Tramadol78 (3.95% of females aged 27 (±5) who take Tramadol)
Pain - Joints in Trazodone Hydrochloride3 (0.48% of females aged 27 (±5) who take Trazodone hydrochloride)
Pain - Joints in Cymbalta26 (0.96% of females aged 27 (±5) who take Cymbalta)
Pain - Joints in Aciphex11 (3.06% of females aged 27 (±5) who take Aciphex)
Pain - Joints in Horizant1 (16.67% of females aged 27 (±5) who take Horizant)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Ibuprofen is effectiven/an/a0.00%
(0 of 1 people)
n/an/an/an/an/a
Tramadol is effectiven/a100.00%
(1 of 1 people)
n/an/an/an/an/an/a
Trazodone Hydrochloride is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Cymbalta is effectiven/a100.00%
(1 of 1 people)
n/an/an/an/an/an/a
Aciphex is effectiven/a100.00%
(1 of 1 people)
n/an/an/an/an/an/a
Horizant is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/aPain - JointsMuscle Weakness (a lack of muscle strength)n/an/an/an/aPostural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright)
Dry MouthPain - JointsTremor (trembling or shaking movements in one or more parts of your body)
Dry Eyes (lack of adequate tears)Insomnia (sleeplessness)Type 2 Diabetes Mellitus
Shortness Of BreathShortness Of BreathBlood Cholesterol Increased
Acid Reflux (stomach acids rise up)Acid Reflux (stomach acids rise up)Hyperglycaemia (high blood sugar)
Muscle Weakness (a lack of muscle strength)Dry MouthDiabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Insomnia (sleeplessness)Dry Eyes (lack of adequate tears)Glycosuria (excretion of glucose into the urine)
Neck PainVertigoDizziness
VertigoNeck PainExtrapyramidal Disorder (involuntary muscle spasms in the face and neck)
Neuropathy Peripheral (surface nerve damage)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Anxiety
- support group for people who have Heartburn
- support group for people who have Insomnia
- support group for people who have Pain
- support group for people who have Acid Reflux
- support group for people who have Dry Eyes
- support group for people who have Dry Mouth
- support group for people who have Insomnia
- support group for people who have Muscle Weakness
- support group for people who have Neck Pain
- support group for people who have Pain - Joints
- support group for people who have Shortness Of Breath
- support group for people who have Vertigo
- support group for people who take Aciphex
- support group for people who take Cymbalta
- support group for people who take Horizant
- support group for people who take Ibuprofen
- support group for people who take Tramadol
- support group for people who take Trazodone Hydrochloride

Recent conversations of related support groups:

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  • Support group for people who have Insomnia
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  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope

Can you answer these questions (Ask a question):

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    Get your medical records
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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