A study of drug interactions between Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl for a Female patient aged 61
This is a personalized study of Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl drug interactions for a 61 year old female patient. The study is created by eHealthMe based on 2 reports from FDA.
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What are the drugs
Humira has active ingredients of adalimumab. It is used in rheumatoid arthritis, crohn's disease, psoriasis, psoriatic arthritis, ankylosing spondylitis, croup.
Methotrexate has active ingredients of methotrexate sodium. It is used in rheumatoid arthritis, psoriatic arthritis, arthritis, psoriasis, systemic lupus erythematosus, psoriatic arthropathy.
Omeprazole has active ingredients of omeprazole. It is used in gastroesophageal reflux disease, gastric ulcer, indigestion, reflux gastritis, stomach discomfort, gastroesophageal reflux in infants.
Diclofenac sodium has active ingredients of diclofenac sodium. It is used in arthritis, pain, back pain - low, inflammation, osteoarthritis, rheumatoid arthritis.
Loperamide has active ingredients of loperamide hydrochloride.
Tramadol hcl has active ingredients of tramadol hydrochloride.
On May, 6, 2013: 2 people who reported to have interactions when taking Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl are studied

Information of the patient in this study:
Age: 61
Gender: female
Conditions: Rheumatoid Arthritis
Drugs taking:
- Humira: used for 2 - 5 years
- Methotrexate
- Omeprazole
- Diclofenac Sodium
- Loperamide
- Tramadol Hcl
Drug interactions have: Weight Decreased, Vomiting, Rheumatoid Arthritis, Diverticulitis, Diarrhoea, Computerised Tomogram Abdomen Abnormal, C-reactive Protein Increased
eHealthMe real world results:
For females aged 61 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Weight Decreased | 2 (100.00%) |
| Vomiting | 2 (100.00%) |
| Rheumatoid Arthritis | 2 (100.00%) |
| Diverticulitis | 2 (100.00%) |
| Diarrhoea | 2 (100.00%) |
| Computerised Tomogram Abdomen Abnormal | 1 (50.00%) |
| C-reactive Protein Increased | 2 (100.00%) |
Most common interactions experienced by females aged 61 (±5) in the use of Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diarrhoea | 2 |
| 2 | Vomiting | 2 |
| 3 | Rheumatoid Arthritis | 2 |
| 4 | Diverticulitis | 2 |
| 5 | Weight Decreased | 2 |
| 6 | C-reactive Protein Increased | 2 |
| 7 | Arthritis | 1 |
| 8 | Computerised Tomogram Abdomen Abnormal | 1 |
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Most common interactions experienced by females aged 61 (±5) in long term use of Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diarrhoea | 2 |
| 2 | Vomiting | 2 |
| 3 | Rheumatoid Arthritis | 2 |
| 4 | Diverticulitis | 2 |
| 5 | Weight Decreased | 2 |
| 6 | C-reactive Protein Increased | 2 |
| 7 | Arthritis | 1 |
| 8 | Computerised Tomogram Abdomen Abnormal | 1 |
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For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Weight Decreased | 2 (100.00%) |
| Vomiting | 2 (100.00%) |
| Rheumatoid Arthritis | 2 (100.00%) |
| Diverticulitis | 2 (100.00%) |
| Diarrhoea | 2 (100.00%) |
| Computerised Tomogram Abdomen Abnormal | 1 (50.00%) |
| C-reactive Protein Increased | 2 (100.00%) |
Most common interactions experienced by people in the use of Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diarrhoea | 2 |
| 2 | Vomiting | 2 |
| 3 | Rheumatoid Arthritis | 2 |
| 4 | Diverticulitis | 2 |
| 5 | Weight Decreased | 2 |
| 6 | C-reactive Protein Increased | 2 |
| 7 | Arthritis | 1 |
| 8 | Computerised Tomogram Abdomen Abnormal | 1 |
Login or sign up (it's free) to view more results. Or personalize this study
Most common interactions experienced by people in long term use of Humira, Methotrexate, Omeprazole, Diclofenac Sodium, Loperamide, Tramadol Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diarrhoea | 2 |
| 2 | Vomiting | 2 |
| 3 | Rheumatoid Arthritis | 2 |
| 4 | Diverticulitis | 2 |
| 5 | Weight Decreased | 2 |
| 6 | C-reactive Protein Increased | 2 |
| 7 | Arthritis | 1 |
| 8 | Computerised Tomogram Abdomen Abnormal | 1 |
Login or sign up (it's free) to view more results. Or personalize this study
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Drug effectiveness in real world:
- Humira for Rheumatoid Arthritis reported by 179 people (updated 5 days ago)
Alternative drugs:
- Rheumatoid Arthritis (46 drugs) (updated 2 days ago)
Comments from related studies:
From this study (2 weeks ago):
From this study (3 weeks ago):
From this study (2 months ago):
I have had leg cramps during the night for a number of years. I started taking Gabapentin January 2013 1 capsule evening then increased to 1 capsule in the morning and one at night. March 28, 2013, reduced to 1 capsule at night for one week and then discontinued. Since then I have had severe leg cramps at night. Sometimes waking up every hour all night long. The pharmacist said that I stopped the medication too soon. During that time I had problems with phlegm. I started taking Allegra. The leg cramps continued and I thought it was the Allegra, so I stopped taking that. I have always had low potassium and I had a blood sample taken today. I will have the results tomorrow, but wondered if any of these medications could cause the leg cramps. They are really very severe. I drink water during the day and have been eating a banana every day for the potassium.
For my son to self catheterise will need a lot of professional help and there may be a need to change his day centre.What would probably be easy for someone of normal abilities will disrupt mysons life as he will need professional help three times a day.
I'm experiencing increasing twitches and spasms in thoracic area.
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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