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Home > Health tools > Drug comparison > Metformin Hydrochloride vs Glipizide

Metformin Hydrochloride vs Glipizide, a side effect and effectiveness comparison for a male patient aged 61

This is personalized comparison of Metformin Hydrochloride vs Glipizide for a male aged 61. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Metformin hydrochloride (latest outcomes from 14,601 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Glipizide (latest outcomes from 22,178 users) has active ingredients of glipizide. It is often used in diabetes.

On Nov, 20, 2014: 15,661 male patients aged 57 who take the same drugs are studied in Metformin Hydrochloride vs Glipizide

Information of patient in study:

GenderAgeReason for the drug
Male57Diabetes Mellitus Management

Drugs to compare:

DrugIngredientsCompany
Metformin Hydrochloride metformin hydrochlorideAndrx Pharms
Glipizide glipizideMylan

eHealthMe real world results:

For males aged 57 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Metformin Hydrochloride (Andrx Pharms)Glipizide (Mylan)
Blood Glucose IncreasedBlood Glucose Increased
Nausea (feeling of having an urge to vomit)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Weight DecreasedNausea (feeling of having an urge to vomit)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Cardiac Failure Congestive
Drug IneffectiveWeight Decreased
Fatigue (feeling of tiredness)Drug Ineffective
DiarrhoeaFatigue (feeling of tiredness)
Renal Failure Acute (rapid kidney dysfunction)Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)Chest Pain
VomitingDyspnoea (difficult or laboured respiration)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Metformin Hydrochloride (Andrx Pharms)Glipizide (Mylan)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal Failure Acute (rapid kidney dysfunction)Cardiac Disorder
Hypertension (high blood pressure)Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria)
Atherosclerosis (disorder of the arteries)Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)Dehydration (dryness resulting from the removal of water)
Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain)Hypoglycaemia (deficiency of glucose in the bloodstream)
Cardiac DisorderCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Type 2 Diabetes MellitusPain
Cardiac Failure CongestiveInjury
Liver InjuryNerve Injury

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Metformin Hydrochloride0.95%17.46%40.80%30.55%10.25%
Glipizide0.00%16.98%49.06%28.30%5.66%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Metformin Hydrochloride (metformin hydrochloride) is often used to treat diabetes. Glipizide (glipizide) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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