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A study for a 56-year old woman who takes Methadone Hydrochloride, Wellbutrin Xl

Summary: 128 female patients aged 56 (±5) who take the same drugs are studied.

This is a personalized study for a 56 year old female patient who has RSD. The study is created by eHealthMe based on reports from FDA and social media.





What are the drugs

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,842 Methadone hydrochloride users)

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 13,296 Wellbutrin xl users)

What are the conditions

Rsd (reflex sympathetic dystrophy) can be treated by Gabapentin, Lyrica, Cymbalta, Amitriptyline Hydrochloride, Neurontin, Percocet. (latest reports from 2,125 Rsd patients)

What is the symptom

Weight gain has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol. (latest reports from 76,545 Weight gain patients)

On Jan, 12, 2015: 128 females aged 52 (±5) who take Methadone Hydrochloride, Wellbutrin Xl are studied

Methadone Hydrochloride, Wellbutrin Xl outcomes

Information of the patient in this study:

Age: 52

Gender: female

Conditions: RSD

Drugs taking:
- Methadone Hydrochloride - 10MG (methadone hydrochloride): used for 10+ years
- Wellbutrin Xl - 300MG (bupropion hydrochloride): used for 10+ years

Drug interactions have: moderate weight gain

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Weight Gain22 (17.19% of females aged 52 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Weight Gain in Rsd16 (7.92% of females aged 52 (±5) who have Rsd)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Weight Gain in Methadone Hydrochloride15 (4.56% of females aged 52 (±5) who take Methadone hydrochloride)
Weight Gain in Wellbutrin Xl53 (2.94% of females aged 52 (±5) who take Wellbutrin xl)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/an/an/a50.00%
(1 of 2 people)
(1 of 1 people)
(1 of 2 people)
(1 of 2 people)
Wellbutrin Xl is effectiven/a0.00%
(0 of 2 people)
(0 of 1 people)
(1 of 1 people)
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dysarthria (speech disorder)Arthralgia (joint pain)PainDrug AbuserDepressionDepressionWeight Gain - UnintentionalPain
Abnormal BehaviourPainFibromyalgia (a long-term condition which causes pain all over the body)Drug DependenceConstipationHeart InjuryAnorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)Anxiety
Drug DependenceHerpes ZosterCataract (clouding of the lens inside the eye)Dysarthria (speech disorder)Heart InjuryHerniated Intervertebral DiskWeight GainOedema Peripheral (superficial swelling)
Tooth Abscess (pus formation in tooth)Oedema Peripheral (superficial swelling)Joint SwellingTooth Abscess (pus formation in tooth)Seasonal Allergy (allergic condition due to certain season)Seasonal Allergy (allergic condition due to certain season)Dry MouthArthralgia (joint pain)
DepressionMyocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Arthralgia (joint pain)DepressionFailed Back Surgery Syndrome (persistent pain following back surgery)High Blood CholesterolPyrexia (fever)
Dental CariesFibromyalgia (a long-term condition which causes pain all over the body)Herpes ZosterDental CariesHerniated Intervertebral DiskFailed Back Surgery Syndrome (persistent pain following back surgery)Injury
Headache (pain in head)Cataract (clouding of the lens inside the eye)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Involuntary Eye MovementsHigh Blood CholesterolConstipationMetastases To Bone (cancer spreads to bone)
Nausea (feeling of having an urge to vomit)Drug IneffectiveOedema Peripheral (superficial swelling)Abnormal BehaviourOsteonecrosis Of Jaw (death of bone of jaw)
DiarrhoeaImmune System DisorderThyroid Neoplasm (tumour of thyroid)Memory Impairment
Partner StressJoint SwellingImmune System DisorderNight Sweats (sweating in night)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who take Methadone Hydrochloride and have Weight Gain
- support group for people who take Wellbutrin Xl and have Weight Gain
- support group for people who have Weight Gain and RSD
- support group for people who have RSD
- support group for people who have Weight Gain
- support group for people who take Methadone Hydrochloride
- support group for people who take Wellbutrin Xl

Can you answer these questions (Ask a question):

  • My sister has been taking depakote cogentin and geodon and suffers with great memory loss inability to carry on a conversation and drops things all the time is this the effect of these drugs? (1 answer)
    Sister takes over 16 perscriptions but the ones mentioned are severe.. due to being bi-polar, and severe agoraphobia and anxiety with this now her life? Not being able to fully comprehend or remember anything? Dropping things and falling when under the full impact of this medication? I either need to get some acceptance or find answers to the effects this medicine is causing..afraid to change up her medicines but needless to say I am worried...
  • Can general anesthesia while taking wellbutrin cause jaw to lock
    after being given relaxing med during general anesthesia administration my jaw locked and my neck stiffened up according to the anesthesiologist. I take 75mg of wellbutrin 2x per day. nurse practitioner in pre-admissions advised me to continue taking the wellbutrin. last dose was the night before surgery. Had severe headaches and stiff neck for weeks following surgery. As a result of the intubation from locked jaw my voice is very hoarse and raspy. and i now have vocal cord polyps. Was there a drug interaction that may have caused a convulsion or seizure type response.
  • Has anyone with a severe chronic cough caused by thick mucus been cured?
    I have suffered from a worsening chronic cough which has never gone away in 8 years. I was allergy tested and had my sinus scanned, x-ray and examined and all seem normal. I have no known allergies. I have a very thick string white mucus which drips down my throat all the time. Eventually I gave up trying to find the cause. The allergist basically called it non allergic rhinitis. No remedy or drug has helped the cough significantly. I have tried all the natural remedies and sinus rinses. I even moved to the seaside for the salt air. No help. It is now to the point that I have a sore throat with a lump feeling all the time and my cough sounds like a dog barking. It wakes me in the night.

    Has anyone been cured of a similar cough?
  • Is colloidal siver the reason my tongue is so painful? help (1 answer)
  • Side effects and drug interactions
    I Have recently been diagnosed with Multiple sclerosis. I am having a relapse. I have tremors throughout my whole body.

    i wanted to compare my medications to see if there are any related side effects or drug interactions that could be related to my tremors?

More questions for: RSD, Weight Gain

You may be interested at these reviews (Write a review):

  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • Lamotrigine severe rash
    I started taking 100mg of Teva-Lamotrigine Nov 22 once daily. I got a refill on Dec 5 that was Mylan-Lamotrigine. Two days later I woke up with an odd hot feeling rash all over my body and severe fatigue. I went back to bed 1/2 hour later after taking my regular Wellbutrin and the Lamotrigine. I woke up late morning. It got progressively worse during the day and I had a headache,fever and chills. I took the anti-histimine Aerius later that day which didn't help. The next day I went to a walk in clinic and they said it wasn't the Lamotrigine and thought it was a virus and did a throat swab. The fever and chills went away after a few days but I still have the rash. Finally after a week I saw a doctor that agreed it was the drug and I am now on the second week of Prednisone steroid treatment and prescription Reactin which is helping slowly. I have reported it to the Mylan drug company.
  • Terbinafine hydrochloride
    I would not reccomend this at all. I was described this drug 6months ago. Bad side effects still ongoing rapid weight gain and water retention in putting on 2 stone in less than 6months. No menstrual in ya year Bloatingin the face arms legs and gut. Been to the doctors said nothing can be done so how much longer can you put up with ffeeling like this.should not be prescribed. Makes you feel dreadfull.
  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.

More reviews for: RSD, Weight Gain

Comments from related studies:

  • From this study (3 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!


    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor


    trust1983 on Dec, 3, 2012:

    Is it true in the states that a psych doc can up and just leave and refuse to treat you because you tried to kill yourself, especially if you didn't have a contact for life with you r doc?


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In-depth study of side effects (who have it, when it happens and how):

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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