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A study of drug interactions between Simvastatin, Propal - Slow Release for a Female patient aged 61

This is a personalized study of Simvastatin, Propal - Slow Release drug interactions for a 61 year old female patient. The study is created by eHealthMe based on 1,471 reports from FDA.

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What are the drugs

Simvastatin has active ingredients of simvastatin. It is used in high blood cholesterol, high blood pressure, hyperlipidaemia, blood cholesterol decreased, coronary heart disease, high density lipoprotein abnormal.

Propal - slow release has active ingredients of potassium chloride.

On Apr, 7, 2013: 1,471 people who reported to have interactions when taking Simvastatin, Propal - Slow Release are studied

Trend of Simvastatin, Propal - Slow Release's drug interactions, side effects, and effectiveness reports (3757507)

Information of the patient in this study:

Age: 61

Gender: female

Conditions: Blood Cholesterol Increased, Blood Pressure Increased

Drugs taking:
- Simvastatin: used for < 1 month
- Propal - Slow Release

Drug interactions have: Myalgia, Muscle Spasms, Malaise, Hypertension, Hepatic Enzyme Increased, Blood Creatine Phosphokinase

eHealthMe real world results:

For females aged 61 (±5):

Comparison with this patient's adverse outcomes:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Myalgia22 (11.22%)
Muscle Spasms7 (3.57%)
Malaise11 (5.61%)
Hypertension71 (36.22%)
Hepatic Enzyme Increased7 (3.57%)
Blood Creatine Phosphokinase4 (2.04%)

Most common interactions experienced by females aged 61 (±5) in the use of Simvastatin, Propal - Slow Release:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
1Hypertension71
2Dyspnoea51
3Asthenia47
4Renal Failure46
5Myocardial Infarction44
6Dizziness36
7Fatigue29
8Pain28
9Fall25
10Nausea22

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Most common interactions experienced by females aged 61 (±5) in long term use of Simvastatin, Propal - Slow Release:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
1Osteitis Deformans3
2Renal Failure3
3Osteomyelitis2
4Abscess2
5Pain2
6Renal Failure Chronic2
7Qrs Axis Abnormal2
8Renal Failure Acute2
9Renal Disorder2
10Pneumonia2

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For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Myalgia76 (5.17%)
Muscle Spasms40 (2.72%)
Malaise40 (2.72%)
Hypertension295 (20.05%)
Hepatic Enzyme Increased11 (0.75%)
Blood Creatine Phosphokinase6 (0.41%)

Most common interactions experienced by people in the use of Simvastatin, Propal - Slow Release:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
1Dyspnoea398
2Hypertension295
3Myocardial Infarction248
4Pain176
5Fatigue173
6Chest Pain167
7Dizziness166
8Cardiac Failure Congestive160
9Nausea142
10Oedema Peripheral127

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Most common interactions experienced by people in long term use of Simvastatin, Propal - Slow Release:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
1Renal Failure18
2Bursitis14
3Pain14
4Osteonecrosis10
5Fall10
6Herpes Zoster9
7Fatigue9
8Cough8
9Spinal Column Stenosis8
10Renal Failure Acute8

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How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Drug effectiveness in real world:

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Comments from related studies:

  • From this study (3 months ago):

  • This is my 3rd year for the Reclast IV. The first year I had no side effects. The second, I had flu-like symptoms for a few days. This year, I began to experience severe musculoskeletal pain the day after I received the infusion. I have migratory pain that affects my ability to walk and perform daily activities. All lab tests came back negative and my doctor concluded that I had an adverse reaction to the Reclast. He says it should have been out of my system within a few weeks, but it has now been 3 months. Is there any hard data on long-term side effects for Reclast beyond anecdotal reports? My doctor has diagnosed me with myoligamentous pain, but Lyrica has limited effectiveness. I am not sure where to go from here. My life has changed dramatically and I have had to give up almost all of my normal activities.

    Reply

  • From this study (5 months ago):

  • Lyme disease - chronic persistent

    Reply

  • From this study (5 months ago):

  • having teeth clenching problems

    Reply

  • From this study (1 year ago):

  • Developed diarrhea followed by 103 fever and vomiting. Liver function enzymes tested high every other test.Lasts one day followed by breathing difficulty for several days. Happens at 6-18 day intervals. Had all tests including colonoscopy,endoscopy and mri. After 5 months was taken off of simvistatin. I was sick three more times but fevers slowly went down and liver function returned to normal.

    Reply

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Related conditions

- High blood cholesterol (9,853 reports)
- High blood pressure (9,853 reports)
- High blood pressure (9,853 reports)
- Muscle spasms (9,853 reports)
- Muscle aches (9,853 reports)

 

Related side effects

- Blood Creatine Phosphokinase
- Hepatic Enzyme Increased
- Hypertension
- Malaise
- Muscle Spasms
- Myalgia

 

 

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