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From FDA reports: drug interactions between Simvastatin, Propal - Slow Release for a Female patient aged 61

This is a personalized study of Simvastatin, Propal - Slow Release drug interactions for a 61 year old female patient. The study is created by eHealthMe based on 1,471 people who take the drugs and have drug interactions.

Information of the patient in this study:

Age: 61

Gender: female

Conditions: Blood Cholesterol Increased, Blood Pressure Increased

Drugs taking:
- Simvastatin: used for < 1 month
- Propal - Slow Release

Drug interactions have: Myalgia, Muscle Spasms, Malaise, Hypertension, Hepatic Enzyme Increased, Blood Creatine Phosphokinase

On Jan, 18, 2014: 1,471 people who reported to have interactions when taking Simvastatin, Propal - Slow Release are studied

Trend of Simvastatin, Propal - Slow Release's drug interactions, side effects, and effectiveness reports (3757507)

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Myalgia (muscle pain)22 (11.22%)
Muscle Spasms (muscle contraction)7 (3.57%)
Malaise (a feeling of general discomfort or uneasiness)11 (5.61%)
Hypertension (high blood pressure)71 (36.22%)
Hepatic Enzyme Increased7 (3.57%)
Blood Creatine Phosphokinase4 (2.04%)

Most common interactions experienced by females aged 61 (±5) in the use of Simvastatin, Propal - Slow Release:

InteractionNumber of reports
Hypertension (high blood pressure)71
Dyspnoea (difficult or laboured respiration)51
Asthenia (weakness)47
Renal Failure (kidney dysfunction)46
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)44
Dizziness36
Fatigue (feeling of tiredness)29
Pain28
Fall25
Nausea (feeling of having an urge to vomit)22

Most common interactions experienced by females aged 61 (±5) in long term use of Simvastatin, Propal - Slow Release:

InteractionNumber of reports
Osteitis Deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)3
Renal Failure (kidney dysfunction)3
Osteomyelitis (infection of bone)2
Abscess (pus)2
Pain2
Renal Failure Chronic (long lasting kidney dysfunction)2
Qrs Axis Abnormal2
Renal Failure Acute (rapid kidney dysfunction)2
Renal Disorder (kidney disease)2
Pneumonia2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Myalgia (muscle pain)76 (5.17%)
Muscle Spasms (muscle contraction)40 (2.72%)
Malaise (a feeling of general discomfort or uneasiness)40 (2.72%)
Hypertension (high blood pressure)295 (20.05%)
Hepatic Enzyme Increased11 (0.75%)
Blood Creatine Phosphokinase6 (0.41%)

Most common interactions experienced by people in the use of Simvastatin, Propal - Slow Release:

InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)398
Hypertension (high blood pressure)295
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)248
Pain176
Fatigue (feeling of tiredness)173
Chest Pain167
Dizziness166
Cardiac Failure Congestive160
Nausea (feeling of having an urge to vomit)142
Oedema Peripheral (superficial swelling)127

Most common interactions experienced by people in long term use of Simvastatin, Propal - Slow Release:

InteractionNumber of reports
Osteonecrosis (death of bone)20
Renal Failure (kidney dysfunction)18
Pain14
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)14
Fall10
Herpes Zoster9
Fatigue (feeling of tiredness)9
Spinal Column Stenosis (narrowing of spinal column)8
Pneumonia8
Osteomyelitis (infection of bone)8

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Blood Cholesterol Increased, Blood Creatine Phosphokinase, Blood Pressure Increased, Hepatic Enzyme Increased, Hypertension, Malaise, Muscle Spasms, Myalgia, Simvastatin

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  • From this study (1 year ago):

  • This is my 3rd year for the Reclast IV. The first year I had no side effects. The second, I had flu-like symptoms for a few days. This year, I began to experience severe musculoskeletal pain the day after I received the infusion. I have migratory pain that affects my ability to walk and perform daily activities. All lab tests came back negative and my doctor concluded that I had an adverse reaction to the Reclast. He says it should have been out of my system within a few weeks, but it has now been 3 months. Is there any hard data on long-term side effects for Reclast beyond anecdotal reports? My doctor has diagnosed me with myoligamentous pain, but Lyrica has limited effectiveness. I am not sure where to go from here. My life has changed dramatically and I have had to give up almost all of my normal activities.

    Reply

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More reviews for: Blood Cholesterol Increased, Blood Creatine Phosphokinase, Blood Pressure Increased, Hepatic Enzyme Increased, Hypertension, Malaise, Muscle Spasms, Myalgia, Simvastatin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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