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What could cause Excessive Eye Blinking for a 65-year old woman who takes Singulair?

Summary: 4,926 female patients aged 65 (±5) who take the same drug are studied.

This is a personalized study for a 65 year old female patient who has Dry eye syndrome. The study is created by eHealthMe based on reports from FDA and social media.

What is the drug

Singulair has active ingredients of montelukast sodium. It is often used in asthma. (latest outcomes from Singulair 42,869 users)

What is the condition

Dry eye syndrome can be treated by Restasis. (latest reports from Dry Eye Syndrome 1,040 patients)

What is the symptom

Excessive eye blinking (excessive blinking is dry eyes) has been reported by people with attention deficit hyperactivity disorder, bipolar disorder, schizophrenia, depression, schizoaffective disorder.(latest reports from Excessive eye blinking 629 patients)

On Dec, 19, 2014: 4,926 females aged 64 (±5) who take Singulair are studied

Singulair outcomes

Information of the patient in this study:

Age: 64

Gender: female

Conditions: Dry eye syndrome

Drugs taking:
- Singulair (montelukast sodium): used for 1 - 2 years

Side effects have: severe excessive eye blinking

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

Side effectNumber of reports on eHealthMe
Excessive Eye Blinking (excessive blinking is dry eyes)3 (0.07% of females aged 64 (±5) who take the drug)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Excessive Eye Blinking in Dry Eye Syndrome1 (2.86% of females aged 64 (±5) who have Dry eye syndrome)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Excessive Eye Blinking in Singulair3 (0.07% of females aged 64 (±5) who take Singulair)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Singulair is effective20.00%
(2 of 10 people)
(7 of 21 people)
(9 of 11 people)
(7 of 14 people)
(15 of 28 people)
(13 of 23 people)
(5 of 16 people)
(0 of 1 people)

Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dyspnoea (difficult or laboured respiration)Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)DepressionInsomnia (sleeplessness)Dyspnoea (difficult or laboured respiration)
Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)Aspartate Aminotransferase IncreasedPain In ExtremityNausea (feeling of having an urge to vomit)Neuropathy Peripheral (surface nerve damage)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)AnxietyAsthma
Stevens-johnson Syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)Alanine Aminotransferase IncreasedLoss Of ConsciousnessDizzinessNausea (feeling of having an urge to vomit)AnxietyNausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Insomnia (sleeplessness)Blood Lactate Dehydrogenase IncreasedVasculitis (inflammation of a blood vessel or blood vessels)Fatigue (feeling of tiredness)Chest PainRotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)Postnasal Drip (discharge from nose)Drug Ineffective
DepressionDepressionWhite Blood Cell Count IncreasedMyalgia (muscle pain)DizzinessStress Fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)Stomach PainCough
Drug HypersensitivityBlood Alkaline Phosphatase IncreasedCardiac Failure CongestiveCoughSuicidal IdeationUrinary Tract DisorderFrequent Headaches (pain in head)Fatigue (feeling of tiredness)
DiarrhoeaWhite Blood Cell Count IncreasedVomitingDepressionUrinary Retention (the inability to completely or partially empty the bladder)Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone)DiarrhoeaHeadache (pain in head)
Liver Disorder (liver diseases)Blood Bilirubin IncreasedNausea (feeling of having an urge to vomit)Rash (redness)DepressionLiver Function Test AbnormalPain In ExtremityPneumonia
Malaise (a feeling of general discomfort or uneasiness)Gamma-glutamyltransferase IncreasedAdverse EventHeadache (pain in head)Cystitis Nos (inflammation of the wall of the bladder)Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)Inherited AllergiesDizziness
Chest PainMalaise (a feeling of general discomfort or uneasiness)PainAbdominal PainFatigue (feeling of tiredness)Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)Arthralgia (joint pain)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who take Singulair and have Excessive Eye Blinking
- support group for people who have Excessive Eye Blinking and Dry eye syndrome
- support group for people who have Dry Eye Syndrome
- support group for people who have Excessive Eye Blinking
- support group for people who take Singulair

Can you answer these questions (Ask a question):

  • Why is it necessary to stop tramadol before cervical myelogram? (1 answer)
    I have been taking tramadol 400 mg a day for 15 years. I was just told to stop cold turkey in preparation for cervical myelogram in 2 days. I'm extremely concerned about withdrawal symptoms! What is the risk of continuing the tramadol?
  • Can metoprolol tartae cause swelling of the feet and legs, fluid retention, weight gain?
    I am adding the other two meds which will not be allowed in the Med List ... Flovent Inhaler, and Motoprolol Tartrate. My Singular prescription is actually Montelukast Sodium ~ I am concerned about my feet and leg swelling with fluid ... this occurred prior to my open heart but after I was doing fine. Now since March 2013 the swelling has returned not as bad. I am doing very well aside from the feet and leg edema. Some days worse than others. I strongly feel it is caused from my taking Metoprolol Tartrate 25 mg. I take one half 12.5mg. in the a.m. and the other half 12.5 mg in the p.m. Please comment asap. Thank You. 17th July 2013

More questions for: Dry eye syndrome, Excessive Eye Blinking

You may be interested at these reviews (Write a review):

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    Antihistamines , even in small amounts, cause my prostate to swell immensely. Several months ago my allergies reached the point I had to take something. I had a physician's sample of 10 mg Singulair, so I took one. To my amazement, I got quick relief from extreme allergies, but my prostate SHRUNK as much as it did on finesteride. Since then I take my usual 2 mg hytrin each morning and my 10 mg Singulair at night and the combo has all but done away with my prostatic hyperplasia. NEVER HEARD OF THIS BEFORE, SO I THOUGHT I WOULD PASS MIT ON.
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    I have never had eczema in my life. A few years ago, in March/April 2012, I began taking birth control (Caziant) for the first time. About a month or two later, I noticed a red patch of skin on my armpit that wouldn't stop itching. I was given different types of fungal creams and corticosteriod creams and they only made it worse. Then, it started spreading to my arms, hands, pelvic, and breasts.

    I was told by doctors and dermatologists that it is eczema and allergies. Had an allergy test done and took out products I was allergic to from my diet and products. I was given singular for the allergies and hydroxyzine for the itching but I still feel itchy and scratch all the time.

    I have been vegan for 10 years, recently gluten free because of a slight allergy, I eat healthy, I stay away from everything I'm allergic to as much as possible, I wash with African black soap and moisturize 2-4 times daily with coco butter and coconut oil, I do not use perfume, I use fragrance free laundry soap and wear gloves when washing dishes. I am doing everything that is suggested but my eczema is only getting worse and spreading to my legs, neck, and face. It is so painful.

    The only thing I can think of is it being correlated to birth control. I have decided to stop taking the pill and hope that it may clear up and go back to how my skin was before taking the pill.
  • Spiriva caused me to swell up like a hippo.
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More reviews for: Dry eye syndrome, Excessive Eye Blinking

Comments from related studies:

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  • From this study (4 days ago):

  • have lost sense of taste and smell


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In-depth study of side effects (who have it, when it happens and how):

Complete drug side effects:

Alternative drugs:

Drugs associated with:

Conditions associated with:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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