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Solaraze vs Efudex, a side effect and effectiveness comparison for a female patient aged 44

This is personalized comparison of Solaraze vs Efudex for a female aged 44. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Solaraze (latest outcomes from 85 users) has active ingredients of diclofenac sodium. It is often used in actinic keratosis.

Efudex (latest outcomes from 402 users) has active ingredients of fluorouracil. It is often used in skin cancer.

What is the symptom

Eye irritation has been reported by people with dry eyes, glaucoma, high blood pressure, rheumatoid arthritis, high blood cholesterol.(latest reports from Eye irritation 8,819 patients)

On Oct, 26, 2014: 3,170 female patients aged 41 who take the same drugs are studied in Solaraze vs Efudex

Information of patient in study:

GenderAgeReason for the drug
Female41Actinic Keratosis

Drugs to compare:

Solaraze diclofenac sodiumNycomed Us
Efudex fluorouracilnot specified

eHealthMe real world results:

For females aged 41 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Solaraze (Nycomed Us)Efudex
Eye Irritation0.00%0.70%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Solaraze (Nycomed Us)Efudex
Pyrexia (fever)Pyrexia (fever)
Arthralgia (joint pain)Nausea (feeling of having an urge to vomit)
Nausea (feeling of having an urge to vomit)Neutropenia (an abnormally low number of neutrophils)
Dyspnoea (difficult or laboured respiration)Febrile Neutropenia (fever with reduced white blood cells)
VomitingDehydration (dryness resulting from the removal of water)
Headache (pain in head)Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)Fatigue (feeling of tiredness)
Chest PainWhite Blood Cell Count Decreased
Fatigue (feeling of tiredness)Abdominal Pain

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Solaraze (Nycomed Us)Efudex
Infertility FemaleDrug Toxicity
CoughDrug Tolerance Decreased
Drug Exposure During PregnancyDrug Hypersensitivity
Restless Legs Syndrome (a powerful urge to move your legs)Dry Skin
Obsessive-compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)Epistaxis (bleed from the nose)
Depression NosFeeling Abnormal
Adult AcneFatigue (feeling of tiredness)
Fatigue (feeling of tiredness)Erythema (redness of the skin)
Attention Deficit/hyperactivity DisorderDecreased Appetite (decreased appetite occurs when you have a reduced desire to eat)
SleepyBack Pain

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Solaraze (diclofenac sodium) is often used to treat actinic keratosis. Efudex (fluorouracil) is often used to treat skin cancer. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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