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Home > Health tools > Drug comparison > Zantac vs Prilosec Otc

Zantac vs Prilosec Otc, a side effect and effectiveness comparison for a male patient aged 49

This is personalized comparison of Zantac vs Prilosec Otc for a male aged 49. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Zantac (latest outcomes from 35,517 users) has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease.

Prilosec otc (latest outcomes from 731 users) has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease.

On Aug, 14, 2014: 3,041 male patients aged 46 who take the same drugs are studied in Zantac vs Prilosec Otc

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Zantac ranitidine hydrochloridenot specified
Prilosec Otc omeprazole magnesiumnot specified

eHealthMe real world results:

For males aged 46 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
ZantacPrilosec Otc
Nausea (feeling of having an urge to vomit)Drug Ineffective
Pyrexia (fever)Pain
Fatigue (feeling of tiredness)Gallbladder Pain
Chest PainMood Swings (an extreme or rapid change in mood)
Dyspnoea (difficult or laboured respiration)Arthralgia (joint pain)
Weight DecreasedInjection Site Irritation
Asthenia (weakness)Pyrexia (fever)
Drug IneffectiveChills (felling of cold)
VomitingPancreatitis Acute (sudden inflammation of pancreas)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Fatigue (feeling of tiredness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
ZantacPrilosec Otc
Blood Lactate Dehydrogenase IncreasedMood Swings (an extreme or rapid change in mood)
Colonic Polyp (extra part of colon tissue grow in intestine)Erectile Dysfunction
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)Fungal Skin Infection
Hepatic Function AbnormalBlood Pressure Increased
Blood Alkaline Phosphatase IncreasedUrinary Frequency Or Urgency
Somnolence (a state of near-sleep, a strong desire for sleep)Pain - Testicle(s) (pain in testes)
Abdominal Pain UpperMyoclonic Jerks (involuntary twitching of a muscle or group of muscles)
Anaemia (lack of blood)Rectal Bleeding (bleeding from rectum)
Hyperlipidaemia (presence of excess lipids in the blood)Liver Abscess (pus in liver)
FractureChest Pressure Sensation (feeling of pressure on chest)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Prilosec Otc1.89%9.43%18.87%45.28%24.53%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Zantac (ranitidine hydrochloride) is often used to treat gastroesophageal reflux disease. Prilosec Otc (omeprazole magnesium) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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