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Zyprexa, Klonopin, Norco, Cortisone Acetate for a 50-year old man





Summary: 952 male patients aged 50 (±5) who take the same drugs are studied.

This is a personalized study for a 50 year old male patient who has Bipolar, Anxiety, Pain, Pain Management. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. (latest outcomes from Zyprexa 43,497 users)

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 31,277 users)

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Norco 6,847 users)

Cortisone acetate has active ingredients of cortisone acetate. It is often used in pain. (latest outcomes from Cortisone acetate 3,397 users)

What are the conditions

Bipolar (mood disorder) can be treated by Lamictal, Lithium Carbonate, Seroquel, Abilify, Lamotrigine, Depakote. (latest reports from Bipolar 43,111 patients)

Anxiety can be treated by Xanax, Klonopin, Clonazepam, Zoloft, Lexapro, Ativan. (latest reports from Anxiety 197,075 patients)

Pain can be treated by Hydrocodone Bitartrate And Acetaminophen, Vicodin, Percocet, Tramadol Hydrochloride, Ibuprofen, Lortab. (latest reports from Pain 280,210 patients)

Pain management can be treated by Percocet, Tramadol Hydrochloride, Vicodin, Hydrocodone Bitartrate And Acetaminophen, Ibuprofen, Oxycontin. (latest reports from Pain Management 248,538 patients)

On Nov, 21, 2014: 952 males aged 47 (±5) who take Zyprexa, Klonopin, Norco, Cortisone Acetate are studied

Zyprexa, Klonopin, Norco, Cortisone Acetate outcomes

Information of the patient in this study:

Age: 47

Gender: male

Conditions: Bipolar, Anxiety, Pain, Pain Management

Drugs taking:
- Zyprexa - 20MG (olanzapine): used for 1 - 6 months
- Klonopin - 2MG (clonazepam): used for 6 - 12 months
- Norco - 325MG;10MG (acetaminophen; hydrocodone bitartrate): used for 1 - 2 years
- Cortisone Acetate - 25MG/ML (cortisone acetate): used for 1 - 2 years

eHealthMe real world results:

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zyprexa is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Klonopin is effectiven/a33.33%
(1 of 3 people)
n/an/a40.00%
(2 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
Norco is effective0.00%
(0 of 1 people)
n/a0.00%
(0 of 2 people)
n/a33.33%
(1 of 3 people)
75.00%
(3 of 4 people)
n/an/a
Cortisone Acetate is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Rectal Haemorrhage (bleeding from anus)Type 2 Diabetes MellitusDiabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Type 2 Diabetes MellitusBlood Triglycerides IncreasedCompleted Suicide (act of taking one's own life)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Epistaxis (bleed from the nose)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Weight IncreasedType 2 Diabetes MellitusNeuropathy Peripheral (surface nerve damage)Type 2 Diabetes MellitusType 2 Diabetes Mellitus
Gingival Bleeding (bleeding gums)AnxietyBlood Triglycerides IncreasedHypertension (high blood pressure)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Neuropathy Peripheral (surface nerve damage)Depression
OverdoseOverdoseBlood Glucose IncreasedPancreatitis (inflammation of pancreas)Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Pain
AggressionAggressionDysuria (painful or difficult urination)Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)Erectile DysfunctionWeight IncreasedAnxiety
Ileus (a painful obstruction of the ileum or other part of the intestine)PneumoniaPrescribed OverdoseVision BlurredDiabetes Mellitus Non-insulin-dependentWeight DecreasedInsomnia (sleeplessness)
PneumoniaNeuropathy Peripheral (surface nerve damage)Thinking AbnormalWeight IncreasedBlood Triglycerides IncreasedErectile DysfunctionWeight Increased
Nightmare (unpleasant dream)Hypertension (high blood pressure)Blood Cholesterol IncreasedBlood Triglycerides IncreasedDepressionHepatic Steatosis (fatty liver disease)Chest Pain
Abnormal DreamsIrritabilityGlucose Urine PresentDiabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus)Hyperglycaemia (high blood sugar)Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)Hypertension (high blood pressure)
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)Nightmare (unpleasant dream)Hypertension (high blood pressure)Diabetes Mellitus Inadequate ControlBipolar Disorder (mood disorder)Chest PainBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Anxiety
- support group for people who have Bipolar
- support group for people who have Pain
- support group for people who have Pain Management
- support group for people who take Cortisone Acetate
- support group for people who take Klonopin
- support group for people who take Norco
- support group for people who take Zyprexa

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Anxiety, Bipolar, Pain, Pain Management

You may be interested at these reviews (Write a review):

  • Low potasium and mood
    While being treated for cancer about 3 years ago and thus taking a number of blood tests, I was diagnosed with low potassium level and prescribed a regular dosage. I had noticed that when I forgot to take my potassium pills, I soon began to feel more depressed than usual and to feel anxious. Taking the ills soon alleviated these symptoms. (I have had depression for most of my life but long ago decided against taking any of the anti-depression Rx pills because I disliked their side effects, especially on my ability to think clearly.) Very recently I finally got around to looking on the Internet to see whether low potassium was associated with mood disorders _ and I found that it was. This site apparently didn't study anyone my age (I'm 78), so I decided to offer these comments. I have at least one grandchild who has been formally diagnosed with depression, and one who is ADHD. Before finding that the relationship of mood and low potassium was formally known, I had suggested to their parent in a low-key way that perhaps she and they should check with their doctors about their potassium levels. Now I'm quite sure that is something they and their doctors should consider. Meanwhile, I am glad to have found formal study of what had been to me only an anecdotal kind of belief that the two were linked. More importantly, in all my years of doctor visits, no doctor and no psychologist has ever mentioned this link to me. Therefore, I hope that somehow this link is brought more to the forefront of medical attention.
  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Restless leg syndrome exasporation while on lovastatim.
    I have been taking Lovastatin for 4 months and have had an increase in my Restless Leg Syndrome. It usually acts up in the afternoon when I'm relaxing. The symptoms seem to go away with rhythmic movement of the affected leg. Usually it is in only one leg at a time. I have also noted a fine tremors in my hands. I consider this as a recurring of the RLS because I have had this before beginning Lovastatin, but it had pretty much abated since then. My doctor back then started me on Amantadine and it worked well.
  • Bipolar patient extremely violent on seraquel
    I have been diagnosed bipolar for over 10 years. 3 years ago I was taken off of topamax and my seraquel was upped to 300 mg from 100 because I was pregnant. I was very violent! Punching, breaking stuff, in jail, in the psych ward. Yes pregnancy and bipolar are not a perfect combination. I too thought it was the hormones. My husband and split several times over me punching him. We moved to a state cross country so there was no more family drama. Nothing worked! Over the last 3 years my life has been hell! I happen to run out of my seroquel (tg) it took 2 weeks to arrive. In that time my body went thru horrible withdrawals. I vowed I wouldn't take it any longer. I've been seraquel free for 2 months. I'm now on gabapentin and proud to say I have no anger issues! Not 1 punch has
    been thrown. I feel like a totally different person.

More reviews for: Anxiety, Bipolar, Pain, Pain Management

Comments from related studies:

  • From this study (2 weeks ago):

  • I have myasthenia gravis and sever joint and muscle pain, Dr. calls this myalgia.
    I have had a lot of tooth decay the last three years with at lest 7 root canals and caps.

    Reply

  • From this study (2 months ago):

  • Is it possible to develop a gluten intolerance from one or a combination of the above medications?

    Reply

  • From this study (3 months ago):

  • My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)

    Reply

    really? on Sep, 22, 2014:

    I honestly thought this was a board where we could all learn from
    Each other's experiences. Unfortunately, everyone seems to be fixated on this one poster, asking a question for a "friend" & who is supposedly mixing all types of drugs. Let's get off of the 3rd party bashing because anyone on all of those drugs needs a lot more than people on a web page. Geez!!!!

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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