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Review: Advair diskus 500/50 side effects

In this review, we analyze Advair diskus 500/50 side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Advair diskus 500/50. The review is based on 319 people who have side effects while taking Advair diskus 500/50 from FDA and social media, and is updated regularly.

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What is Advair diskus 500/50

Advair diskus 500/50 (latest outcomes from 444 users) has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma.

Other drugs that have the same active ingredients (fluticasone propionate; salmeterol xinafoate): Advair Diskus 100/50, Advair Diskus 250/50, Advair Hfa.

On Dec, 12, 2014: 319 people who reported to have side effects when taking Advair diskus 500/50 are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Headache (pain in head)Dyspnoea (difficult or laboured respiration)Syncope (loss of consciousness with an inability to maintain postural tone)Muscle Spasms (muscle contraction)DepressionFatigue (feeling of tiredness)Arthritis (form of joint disorder that involves inflammation of one or more joints)Pneumonia
Drug IneffectiveMyalgia (muscle pain)DizzinessNumbness And Tingling (unusual prickling sensations)Weight IncreasedMuscle TwitchingDry SkinDyspnoea (difficult or laboured respiration)
Dyspnoea (difficult or laboured respiration)Condition AggravatedMuscle Cramp (painful sensation caused by muscle contraction)Granuloma Annulare (reddish bumps on the skin arranged in a circle or ring)Fungal InfectionAscites (accumulation of fluid in the abdominal cavity)Urticaria (rash of round, red welts on the skin that itch intensely)Hypoxia (low oxygen conditions)
Pharyngolaryngeal PainDysphonia (speech disorder attributable to a disorder of phonation)Arthralgia (joint pain)Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)Headache (pain in head)ConstipationChronic Depression (long lasting stress state of low mood)Death
Dry ThroatDizzinessAlopecia (absence of hair from areas of the body)Candidal Infection NosPainPotassium - Low (low potassium)Cataract (clouding of the lens inside the eye)Insomnia (sleeplessness)
Muscle Spasms (muscle contraction)AsthmaSwellingPneumoniaDysphonia (speech disorder attributable to a disorder of phonation)Gas - Belching (act of expelling air from the stomach through the mouth)Intraocular Pressure IncreasedDrug Ineffective
CoughSpeech DisorderDysgeusia (disorder of the sense of taste)Gastric Disorder (disease of stomach)Cataract (clouding of the lens inside the eye)Cholesterol TestExhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Palpitations (feelings or sensations that your heart is pounding or racing)
AnxietyNausea (feeling of having an urge to vomit)Drug IneffectiveCandidiasis (candidiasis or thrush is a fungal infection)Liver Cirrhosis (end result of chronic liver damage caused by chronic liver disease)Diplopia (double vision)Weight IncreasedAsthma
Dysphonia (speech disorder attributable to a disorder of phonation)Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)Muscle Spasms (muscle contraction)Ageusia (loss of taste functions of the tongue)Malaise (a feeling of general discomfort or uneasiness)Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Wheezing (a high-pitched whistling sound made while you breath)
Vision BlurredSwollen Tongue (swelling of tongue)Dysphonia (speech disorder attributable to a disorder of phonation)Fatigue (feeling of tiredness)Cough AggravatedCataract (clouding of the lens inside the eye)Mood Swings (an extreme or rapid change in mood)Viral Infection

Most common side effects by gender * :

Dyspnoea (difficult or laboured respiration)Drug Ineffective
Headache (pain in head)Dyspnoea (difficult or laboured respiration)
Weight IncreasedCough
Palpitations (feelings or sensations that your heart is pounding or racing)Dysphonia (speech disorder attributable to a disorder of phonation)
Condition AggravatedVision Blurred
Muscle Spasms (muscle contraction)Tremor (trembling or shaking movements in one or more parts of your body)
Myalgia (muscle pain)Asthma
Drug IneffectiveNausea (feeling of having an urge to vomit)
Pharyngolaryngeal PainOedema (fluid collection in tissue)

Most common side effects by age * :

n/aMuscle Cramp (painful sensation caused by muscle contraction)Dyspnoea (difficult or laboured respiration)Loss Of DreamingHeadache (pain in head)Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)Vision Blurred
Arthralgia (joint pain)Syncope (loss of consciousness with an inability to maintain postural tone)Malaise (a feeling of general discomfort or uneasiness)Weight IncreasedAsthmaPneumoniaDrug Ineffective
Alopecia (absence of hair from areas of the body)Pallor (unusual lightness of skin colour)Poor Quality SleepVision BlurredMyalgia (muscle pain)Headache (pain in head)Dyspnoea (difficult or laboured respiration)
SwellingBurning Sensation NosInsomnia (sleeplessness)Tremor (trembling or shaking movements in one or more parts of your body)Fatigue (feeling of tiredness)Hypoxia (low oxygen conditions)Muscle Spasms (muscle contraction)
Weight IncreasedLoss Of ConsciousnessImpaired Work AbilityChest PainBack PainNausea (feeling of having an urge to vomit)Liver Cirrhosis (end result of chronic liver damage caused by chronic liver disease)
Drug IneffectiveHyperhidrosis (abnormally increased sweating)Fatigue (feeling of tiredness)Pharyngolaryngeal PainCondition AggravatedCoughPneumonia
AsthmaCollapse (sudden functional breakdown)Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)Insomnia (sleeplessness)Collapse Of Lung (functional breakdown of lung)Speech DisorderMyocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Suicidal BehaviourPharyngolaryngeal PainQuality Of Life DecreasedDepressionDrug IneffectiveDizzinessOedema Lower Limb (fluid collection in tissue of lower leg)
Self MutilationGlaucoma (increased fluid pressure in the eye with vision loss)Sleep Apnoea Syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)Syncope (loss of consciousness with an inability to maintain postural tone)Throat TightnessPainWheezing (a high-pitched whistling sound made while you breath)
CryingMigraine (headache)Injection Site PainDry ThroatInsomnia (sleeplessness)AnxietyVisual Acuity Reduced (reduced clearness of vision)

* Some reports may have incomplete information.

Browse Advair diskus 500/50 side effects from A to Z:

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Are you taking Advair diskus 500/50?

Comments from related studies:

  • From this study (4 weeks ago):

  • had a procedure to melt and remove fat from abdomen ... used versed IV as anaesthesia, wasn't very effective, had a lot of pain and memory of procedure. Rash developed on my face around mouth, nose, and eyes ... getting worse over past 18 months.


  • From this study (4 weeks ago):

  • cannot eat well, mouth is very painful!


  • From this study (2 months ago):

  • Stage IV breast cancer with mets to bones. C5 in neck collapse. No surgery. Bone mets are significant in skull and neck. Symptoms are neck and shoulder pain, taking methadone for this. Severe fatigue and lethargy especially after zometa infusion. Zometa infusion every 3 months.


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Can you answer these questions (Ask a question):

  • Why would i get copd since i never smoked?
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.
  • Dr. switched me from advair and spiriva to tudorza. shouldn't i still stay with advair
    Doc said drop Spiriva AND Advair and start exclusively on Tudorza.

    Wouldn't staying with Advair in addition to Tudorza be helpful?

    (Or would it decrease Tudorza's effectiveness?)

    I'm just finishing a 3-month bout with lung Pseudomonas infection. I'm regaining my strength, but still breath much more poorly upon (even minimal) exertion than before the Pseuomonas.

    Tudorza seems as equally effective as my Advair and Spiriva regimens did, but I still run out of breath much sooner than I did before the Pseudomonas hit.

    Will I ever regain my prior abilities? Should I combine ADVAIR with TUDORZA?

  • Is it possible for me to stop taking advair without getting short of breath (1 answer)
    I take these meds everyday the singulair I take one a day and the Advair I take twice a day. I take vitamin C on occasions. I do not feel bad but there are times when I have bad indegestion. Also my face is getting very round and I would like to know why? Is there any way I can maybe stop taking the advair? is there an alternative med
  • Do you have nausea every day
    I was diagnosed with COPD 3 years ago. I quit smoking for a short while but picked it back up. I use a c-pap machine at night and every morning I wake up nauseated and it usually last through out the day. I'm wondering if anyone else experiences this.
  • Are there reports of advair diskus 250/50 causing hepatitis c
    I have been taking Advair Diskus 250/50 for 8 years and was diagnosed with Hepatitis c 2 and a half years.

More questions for: Advair diskus 500/50

You may be interested at these reviews (Write a review):

  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Advair could have caused current dark circles around eyes
    I have had asthma my entire life. I was introduced to advair during an asthma study when I was 16 I think. I have been on the medication ever since. I am 27 now and have been off Advair 250 for almost 7 months now. Lately I have been experiences very dark redish circles underneath and around my eyes. They get darker and lighter depending on my mood I guess. I did not have this problem prior to ever being on this medication. Does anyone else have similar symptoms or story? How do I make them go away?
  • Treating copd and kidney disease (1 response)
    My biggest problem is trying to keep my blood pressure at 110 to 140 diastolic and controlling constipation.

More reviews for: Advair diskus 500/50

On eHealthMe, Advair Diskus 500/50 (fluticasone propionate; salmeterol xinafoate) is often used for asthma. Find out below the conditions Advair Diskus 500/50 is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Advair Diskus 500/50 used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Advair diskus 500/50 drug interactions:

Browse Advair diskus 500/50 drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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