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Review: Allopurinol side effects

In this review, we analyze Allopurinol side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Allopurinol. The review is based on 50,583 people who have side effects while taking Allopurinol from FDA and social media, and is updated regularly.

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What is Allopurinol

Allopurinol (latest outcomes from 51,468 users) has active ingredients of allopurinol. It is often used in gout.

Other drugs that have the same active ingredients (allopurinol): Zyloprim, Lopurin.

On Mar, 15, 2015: 50,583 people who reported to have side effects when taking Allopurinol are studied

 outcomes

Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pyrexia (fever)Pyrexia (fever)Blood Creatinine IncreasedRenal Failure Acute (rapid kidney dysfunction)Renal Failure Acute (rapid kidney dysfunction)DiarrhoeaPulmonary Embolism (blockage of the main artery of the lung)Dyspnoea (difficult or laboured respiration)
Renal Failure Acute (rapid kidney dysfunction)Platelet Count DecreasedPyrexia (fever)Anaemia (lack of blood)Interstitial Lung DiseaseC-reactive Protein IncreasedWeight DecreasedAnaemia (lack of blood)
Sepsis (a severe blood infection that can lead to organ failure and death)PneumoniaGeneral Physical Health Deterioration (weak health status)Pyrexia (fever)Thrombocytopenia (decrease of platelets in blood)Pyrexia (fever)Osteomyelitis (infection of bone)Diarrhoea
Stevens-johnson Syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)Renal Failure Acute (rapid kidney dysfunction)Rash (redness)Blood Creatinine IncreasedPyrexia (fever)Pleural Effusion (water on the lungs)Tinnitus (a ringing in the ears)Pain
Renal Failure (kidney dysfunction)Anaemia (lack of blood)Renal Failure (kidney dysfunction)DiarrhoeaRenal Failure (kidney dysfunction)Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)PneumoniaNausea (feeling of having an urge to vomit)
Hypotension (abnormally low blood pressure)Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash)Renal Failure Acute (rapid kidney dysfunction)Renal Failure (kidney dysfunction)DiarrhoeaInterstitial Lung DiseaseDyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
PneumoniaDiarrhoeaAnaemia (lack of blood)Dehydration (dryness resulting from the removal of water)Blood Creatine Phosphokinase IncreasedNausea (feeling of having an urge to vomit)Leukopenia (less number of white blood cells in blood)Renal Failure Acute (rapid kidney dysfunction)
Febrile Neutropenia (fever with reduced white blood cells)Stevens-johnson Syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)Renal Impairment (severely reduced kidney function)Renal Impairment (severely reduced kidney function)Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)Dyspnoea (difficult or laboured respiration)Renal Failure (kidney dysfunction)Renal Failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)Rash (redness)Cardiac FailureCardiac FailureRenal Impairment (severely reduced kidney function)Renal Failure (kidney dysfunction)Hypoxia (low oxygen conditions)Pyrexia (fever)
DiarrhoeaRenal Failure (kidney dysfunction)Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Fatigue (feeling of tiredness)Renal Failure Chronic (long lasting kidney dysfunction)DizzinessOral Herpes (viral infection of mouth)Asthenia (weakness)

Most common side effects by gender * :

FemaleMale
Nausea (feeling of having an urge to vomit)Pyrexia (fever)
Pyrexia (fever)Dyspnoea (difficult or laboured respiration)
Renal Failure Acute (rapid kidney dysfunction)Renal Failure Acute (rapid kidney dysfunction)
Anaemia (lack of blood)Nausea (feeling of having an urge to vomit)
DiarrhoeaDiarrhoea
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Asthenia (weakness)Renal Failure (kidney dysfunction)
Fatigue (feeling of tiredness)Anaemia (lack of blood)
PainAsthenia (weakness)
VomitingPneumonia

Most common side effects by age * :

0-12-910-1920-2930-3940-4950-5960+
Toxic Epidermal Necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)Pyrexia (fever)Hepatotoxicity (chemical-driven liver damage)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Renal Failure Acute (rapid kidney dysfunction)
Premature BabyCoughBlood Bilirubin IncreasedFebrile Neutropenia (fever with reduced white blood cells)Fatigue (feeling of tiredness)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Pyrexia (fever)
Hypoglycaemia Neonatal (deficiency of glucose in the bloodstream in neonatal)Tumour Lysis Syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)Dilatation Intrahepatic Duct AcquiredPlatelet Count DecreasedHeadache (pain in head)Dyspnoea (difficult or laboured respiration)DiarrhoeaDyspnoea (difficult or laboured respiration)
Neonatal Respiratory Distress Syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)Neutropenia (an abnormally low number of neutrophils)Alanine Aminotransferase IncreasedNausea (feeling of having an urge to vomit)Alanine Aminotransferase IncreasedPainDyspnoea (difficult or laboured respiration)Nausea (feeling of having an urge to vomit)
Jaundice Neonatal (yellowing of skin in neonate)Febrile Neutropenia (fever with reduced white blood cells)Liver Function Test AbnormalDyspnoea (difficult or laboured respiration)AnxietyFatigue (feeling of tiredness)Fatigue (feeling of tiredness)Anaemia (lack of blood)
Foetal Cerebrovascular Disorder (a group of brain dysfunctions related to disease of the blood vessels supplying the brain of foetus)Attention Deficit/hyperactivity DisorderPyrexia (fever)Alanine Aminotransferase IncreasedNausea (feeling of having an urge to vomit)Renal Failure Acute (rapid kidney dysfunction)Anaemia (lack of blood)Diarrhoea
Placental DisorderCytomegalovirus InfectionHypotension (abnormally low blood pressure)VomitingHypotension (abnormally low blood pressure)DiarrhoeaPainRenal Failure (kidney dysfunction)
Pyrexia (fever)Renal Failure Acute (rapid kidney dysfunction)Venoocclusive Liver Disease (small veins in the liver are obstructed)DiarrhoeaMalaise (a feeling of general discomfort or uneasiness)Asthenia (weakness)Renal Failure Acute (rapid kidney dysfunction)Asthenia (weakness)
Chloroma (green-coloured tumour)Venoocclusive Liver Disease (small veins in the liver are obstructed)Blood Alkaline Phosphatase IncreasedAspartate Aminotransferase IncreasedDizzinessBlood Creatinine IncreasedOedema Peripheral (superficial swelling)Fatigue (feeling of tiredness)
Drug Exposure During PregnancyChronic Sinusitis (long lasting inflammation of the paranasal sinuses)Renal Failure (kidney dysfunction)White Blood Cell Count DecreasedAspartate Aminotransferase IncreasedArthralgia (joint pain)Hypotension (abnormally low blood pressure)Blood Creatinine Increased

* Some reports may have incomplete information.

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On eHealthMe, Allopurinol (allopurinol) is often used for gout. Find out below the conditions Allopurinol is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Allopurinol used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Allopurinol drug interactions:

Browse Allopurinol drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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