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Review: Allopurinol side effects

In this review, we analyze Allopurinol side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Allopurinol. The review is based on 50,519 people who have side effects while taking Allopurinol from FDA and social media, and is updated regularly.

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What is Allopurinol

Allopurinol (latest outcomes from 51,399 users) has active ingredients of allopurinol. It is often used in gout.

Other drugs that have the same active ingredients (allopurinol): Zyloprim, Lopurin.

On Aug, 22, 2014: 50,519 people who reported to have side effects when taking Allopurinol are studied

 outcomes

Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaBlood Creatinine IncreasedRenal Failure AcuteRenal Failure AcuteDiarrhoeaPulmonary EmbolismDyspnoea
Renal Failure AcutePlatelet Count DecreasedPyrexiaAnaemiaInterstitial Lung DiseaseC-reactive Protein IncreasedWeight DecreasedAnaemia
SepsisPneumoniaRashPyrexiaThrombocytopeniaPyrexiaPneumoniaDiarrhoea
Stevens-johnson SyndromeRenal Failure AcuteGeneral Physical Health DeteriorationBlood Creatinine IncreasedPyrexiaPleural EffusionTinnitusPain
Renal FailureAnaemiaRenal Failure AcuteDiarrhoeaRenal FailureDecreased AppetiteOsteomyelitisNausea
HypotensionDrug Rash With Eosinophilia And Systemic SymptomsRenal FailureRenal FailureDiarrhoeaNauseaDyspnoeaFatigue
PneumoniaDiarrhoeaAnaemiaDehydrationBlood Creatine Phosphokinase IncreasedDyspnoeaLeukopeniaRenal Failure Acute
Febrile NeutropeniaStevens-johnson SyndromeRenal ImpairmentRenal ImpairmentAtrial FibrillationInterstitial Lung DiseaseRenal FailureRenal Failure
ThrombocytopeniaRashCardiac FailureCardiac FailureRenal ImpairmentRenal FailureHypoxiaPyrexia
DiarrhoeaRenal FailurePancytopeniaAtrial FibrillationMyalgiaDizzinessOral HerpesAsthenia

Most common side effects by gender * :

FemaleMale
NauseaPyrexia
PyrexiaDyspnoea
Renal Failure AcuteRenal Failure Acute
AnaemiaNausea
DiarrhoeaDiarrhoea
DyspnoeaFatigue
AstheniaRenal Failure
FatigueAnaemia
PainAsthenia
VomitingPneumonia

Most common side effects by age * :

0-12-910-1920-2930-3940-4950-5960+
Toxic Epidermal NecrolysisPyrexiaHepatotoxicityPyrexiaPyrexiaPyrexiaPyrexiaRenal Failure Acute
Premature BabyCoughBlood Bilirubin IncreasedFebrile NeutropeniaFatigueNauseaNauseaPyrexia
Hypoglycaemia NeonatalTumour Lysis SyndromeDilatation Intrahepatic Duct AcquiredPlatelet Count DecreasedHeadacheDyspnoeaDiarrhoeaDyspnoea
Neonatal Respiratory Distress SyndromeNeutropeniaAlanine Aminotransferase IncreasedNauseaAlanine Aminotransferase IncreasedPainDyspnoeaNausea
Jaundice NeonatalFebrile NeutropeniaLiver Function Test AbnormalDyspnoeaAnxietyFatigueFatigueAnaemia
Foetal Cerebrovascular DisorderAttention Deficit/hyperactivity DisorderPyrexiaDiarrhoeaNauseaRenal Failure AcuteAnaemiaDiarrhoea
Placental DisorderCytomegalovirus InfectionHypotensionAlanine Aminotransferase IncreasedHypotensionDiarrhoeaPainRenal Failure
PyrexiaRenal Failure AcuteVenoocclusive Liver DiseaseVomitingMalaiseAstheniaRenal Failure AcuteAsthenia
ChloromaVenoocclusive Liver DiseaseBlood Alkaline Phosphatase IncreasedAspartate Aminotransferase IncreasedDizzinessBlood Creatinine IncreasedOedema PeripheralFatigue
Foetal Growth RestrictionChronic SinusitisRenal FailureWhite Blood Cell Count DecreasedAspartate Aminotransferase IncreasedArthralgiaHypotensionBlood Creatinine Increased

* Some reports may have incomplete information.

Browse Allopurinol side effects from A to Z:

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Comments from related studies:

  • From this study (2 days ago):

  • Still taking drug but noticed extreme anger and lack of tolerance and zero patients after being on the drug for only 3 weeks

    Reply

  • From this study (2 weeks ago):

  • During exertion, experience shortness of breath and burning in leg muscles. Observed low heart rate.

    Reply

    Carlos on Jul, 16, 2014:

    I have the same symptoms, especially low heart rate (This happens progressively when doing exercise for long time (months)). I have been told that I possibly suffer for a carnitine deficiency and/or fatty acid oxidation disorder.

    Reply

  • From this study (2 weeks ago):

  • Since I have been on diclofenac I started having hot flashes all day and night long. I am wondering if this is a side effect of the diclofenac.

    Reply

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    I began taking Allopurinol 100mg to help metabolize the Purinethol I have been taking for 6 years for Crohn's disease after a blood test revealed my 6-MMP metabolites were too high and 6-TG were too low. Several published studies show Allopurinol to be helpful for "non-preferential metabolizers" lik ...

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    I have just been prescribed 100mg Allopurinol. 1 a day. I am in my second day of taking these tablets. I have begun to get get a sudden pain in my ear. I have never in all my years have ever had such a pain. I know the only change that has happened around me is taking these tablets. I have sto ...

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    Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different presc ...

More reviews for: Allopurinol

On eHealthMe, Allopurinol (allopurinol) is often used for gout. Find out below the conditions Allopurinol is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Allopurinol used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Allopurinol drug interactions:

Browse Allopurinol drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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