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Review: Allopurinol side effects

In this review, we analyze Allopurinol side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Allopurinol. The review is based on 50,545 people who have side effects while taking Allopurinol from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who have Allopurinol side effects >>>

What is Allopurinol

Allopurinol (latest outcomes from 51,429 users) has active ingredients of allopurinol. It is often used in gout.

Other drugs that have the same active ingredients (allopurinol): Zyloprim, Lopurin.

On Oct, 13, 2014: 50,545 people who reported to have side effects when taking Allopurinol are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaBlood Creatinine IncreasedRenal Failure AcuteRenal Failure AcuteDiarrhoeaPulmonary EmbolismDyspnoea
Renal Failure AcutePlatelet Count DecreasedPyrexiaAnaemiaInterstitial Lung DiseaseC-reactive Protein IncreasedWeight DecreasedAnaemia
Stevens-johnson SyndromeRenal Failure AcuteGeneral Physical Health DeteriorationBlood Creatinine IncreasedPyrexiaPleural EffusionTinnitusPain
Renal FailureAnaemiaRenal FailureDiarrhoeaRenal FailureDecreased AppetiteOsteomyelitisNausea
HypotensionDrug Rash With Eosinophilia And Systemic SymptomsRenal Failure AcuteRenal FailureDiarrhoeaNauseaDyspnoeaFatigue
PneumoniaDiarrhoeaAnaemiaDehydrationBlood Creatine Phosphokinase IncreasedDyspnoeaLeukopeniaRenal Failure Acute
Febrile NeutropeniaStevens-johnson SyndromeRenal ImpairmentRenal ImpairmentAtrial FibrillationInterstitial Lung DiseaseRenal FailureRenal Failure
ThrombocytopeniaRashCardiac FailureCardiac FailureRenal ImpairmentRenal FailureHypoxiaPyrexia
DiarrhoeaRenal FailureDiarrhoeaFatigueRenal Failure ChronicDizzinessOral HerpesAsthenia

Most common side effects by gender * :

Renal Failure AcuteRenal Failure Acute
AstheniaRenal Failure

Most common side effects by age * :

Toxic Epidermal NecrolysisPyrexiaHepatotoxicityPyrexiaPyrexiaPyrexiaPyrexiaRenal Failure Acute
Premature BabyCoughBlood Bilirubin IncreasedFebrile NeutropeniaFatigueNauseaNauseaPyrexia
Hypoglycaemia NeonatalTumour Lysis SyndromeDilatation Intrahepatic Duct AcquiredPlatelet Count DecreasedHeadacheDyspnoeaDiarrhoeaDyspnoea
Neonatal Respiratory Distress SyndromeNeutropeniaAlanine Aminotransferase IncreasedNauseaAlanine Aminotransferase IncreasedPainDyspnoeaNausea
Jaundice NeonatalFebrile NeutropeniaLiver Function Test AbnormalDyspnoeaAnxietyFatigueFatigueAnaemia
Foetal Cerebrovascular DisorderAttention Deficit/hyperactivity DisorderPyrexiaVomitingNauseaRenal Failure AcuteAnaemiaDiarrhoea
Placental DisorderCytomegalovirus InfectionHypotensionAlanine Aminotransferase IncreasedHypotensionDiarrhoeaPainRenal Failure
PyrexiaRenal Failure AcuteVenoocclusive Liver DiseaseDiarrhoeaMalaiseAstheniaRenal Failure AcuteAsthenia
ChloromaVenoocclusive Liver DiseaseBlood Alkaline Phosphatase IncreasedAspartate Aminotransferase IncreasedDizzinessBlood Creatinine IncreasedOedema PeripheralFatigue
Foetal Growth RestrictionChronic SinusitisRenal FailureWhite Blood Cell Count DecreasedAspartate Aminotransferase IncreasedArthralgiaHypotensionBlood Creatinine Increased

* Some reports may have incomplete information.

Browse Allopurinol side effects from A to Z:

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Are you taking Allopurinol?

Comments from related studies:

  • From this study (1 day ago):

  • I have been diagnosed with IBS, but I have reason to believe that maybe taking Allopurinol for the last 8 years for Gout may have some effect on my condition. I understand that 300 mg may be too strong for me. My last uric acid level was 3.1 which is in the normal range...should I reduce my amount of the medication to 1/2? Also, I have not been taking the medication after a meal, but at night before I go to bed. Any advice.


  • From this study (2 days ago):

  • Low testosterone in the low 100s


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    I began taking Allopurinol 100mg to help metabolize the Purinethol I have been taking for 6 years for Crohn's disease after a blood test revealed my 6-MMP metabolites were too high and 6-TG were too low. Several published studies show Allopurinol to be helpful for "non-preferential metabolizers" lik ...

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    I have just been prescribed 100mg Allopurinol. 1 a day. I am in my second day of taking these tablets. I have begun to get get a sudden pain in my ear. I have never in all my years have ever had such a pain. I know the only change that has happened around me is taking these tablets. I have sto ...

More reviews for: Allopurinol

On eHealthMe, Allopurinol (allopurinol) is often used for gout. Find out below the conditions Allopurinol is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Allopurinol used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Allopurinol drug interactions:

Browse Allopurinol drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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