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Review: Amitriptyline side effects

In this review, we analyze Amitriptyline hydrochloride side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Amitriptyline hydrochloride. The review is based on 5,671 people who have side effects while taking Amitriptyline hydrochloride from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who have Amitriptyline side effects >>>

What is Amitriptyline hydrochloride

Amitriptyline hydrochloride (latest outcomes from 7,085 users) has active ingredients of amitriptyline hydrochloride. It is often used in depression.

Other drugs that have the same active ingredients (amitriptyline hydrochloride): Elavil, Endep, Amitril, Amitid.

On Aug, 25, 2014: 5,671 people who reported to have side effects when taking Amitriptyline hydrochloride are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ComaPanic AttackHypertensionDizzinessCerebrovascular AccidentFistulaDizzinessNausea
FallIrritable Bowel SyndromeMood SwingsDry MouthAnxietyFatigueConfusionFatigue
DepressionArthralgiaLethargyConfusional StateOsteonecrosisTemporomandibular Joint SyndromeRash GeneralisedFall
Suicide AttemptNauseaPancreatitisInsomniaBlood Creatine Phosphokinase IncreasedDrug Administration ErrorDiarrheaArthralgia
HallucinationHeart Rate IncreasedNauseaTremorCellulitisInfectionTremorAnxiety
RestlessnessDiarrhoeaDizzinessHyponatraemiaBlood Cholesterol IncreasedArthropathyItching ScarDyspnoea
SyncopeAbdominal Pain UpperChest PainAbnormal Behaviour NosAmnesiaOsteitis DeformansHair LossHeadache
DizzinessHypertensionBone And Joint PainAnorexiaWeight DecreasedHerpes ZosterNight SweatsPain
SomnolenceDizzinessSerotonin SyndromeCondition AggravatedTransient Ischaemic AttackPainSkin Blushing/flushingDepression
TremorReflexes AbnormalDrug Exposure During PregnancyDisorientationHaematocheziaRheumatoid ArthritisMental Status ChangesDizziness

Most common side effects by gender * :

DepressionConfusional State

Most common side effects by age * :

Maternal Drugs Affecting FoetusAsthmaAbdominal PainPyrexiaNauseaNauseaFatigueFall
MacrocytosisNasopharyngitisHeart Rate IncreasedSuicide AttemptDepressionFatigueFallNausea
HypertriglyceridaemiaPallorHeadacheSerotonin SyndromeChest PainDrug IneffectivePyrexiaPyrexia
NeutropeniaRespiratory Disorder NosDrug IneffectiveHeadacheDizzinessPainDepressionArthralgia
Drug Withdrawal Syndrome NeonatalSedationAbasiaDrug ToxicityAnxietyDepressionNauseaFatigue
Poisoning DeliberateFacial PalsyPyrexiaIntentional OverdoseDyspnoeaVomitingAnxietyDyspnoea
Foetal Distress SyndromeHemiparesisPain In ExtremityHypotensionSuicide AttemptAnxietyHeadacheAsthenia
Drug Exposure During PregnancyHypotoniaAggressionLoss Of ConsciousnessFatigueBack PainPainAnxiety
Blood Creatinine IncreasedMydriasisCrohn's DiseaseSomnolenceParaesthesiaDizzinessDrug IneffectiveDizziness
Foetal Growth RetardationTremor NecConvulsionCondition AggravatedConvulsionHeadacheDizzinessDiarrhoea

* Some reports may have incomplete information.

Browse Amitriptyline hydrochloride side effects from A to Z:

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Comments from related studies:

  • From this study (2 weeks ago):

  • Elavil, 25mg @ night stopped an 11 month chronic headache after a head injury, I sustained 1 1/2 years ago.
    Additionally, Neurologist prescribed 100 mg Lyrica for chronic back/nerve pain from moderate/severe spinal injuries, sustained 20+ years earlier. (Crushed/cracked verabrae and 3 intervertebral disc bulges)
    I had been using Ibuprofen daily in moderate to heavy dosage for the last 20+ years. (800+ mg daily B/4 and then continually after recent head injury)
    I was advised to stop/reduce use of Motrin to 1/2 month or less. It is still the best pain relief but have reduced to PRN, perhaps 200 mg alternate days.
    Since treatment with Lyrica I've noticed reduced nerve pain and stopped using Elavil for sake of not feeling so "wrecked" in the mornings. I have also developed a severe sleep apnoea, treated unsuccessfully via CPAP device which is unbearable to use. I have subsequently suffered with depression/mood disorder for 20+ years and am currently un-treated for this long-standing vulnerability which came back with a vengence after the head-injury. I feel irregularity to my heart beat by the end of the day. I feel suicidal and violently angry.


  • From this study (2 weeks ago):

  • Peripheral neuropathy cause is unknown. Not diabetic. No Lupus. No MS.


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More reviews for: Amitriptyline hydrochloride

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used for migraine. Find out below the conditions Amitriptyline Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Amitriptyline Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Amitriptyline hydrochloride drug interactions:

Browse Amitriptyline hydrochloride drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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