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Review: Bactrim side effects

In this review, we analyze Bactrim side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Bactrim. The review is based on 28,160 people who have side effects while taking Bactrim from FDA and social media, and is updated regularly.

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What is Bactrim

Bactrim (latest outcomes from 29,487 users) has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection.

Other drugs that have the same active ingredients (sulfamethoxazole; trimethoprim): Septra, Septra Ds, Bactrim Ds, Bactrim Pediatric, Septra Grape, Sulfamethoxazole And Trimethoprim, Sulfamethoxazole And Trimethoprim Double Strength, Sulfatrim Pediatric, Sulfatrim, Sulfamethoprim, Sulfamethoxazole And Trimethoprim Single Strength, Sulfamethoprim-ds, Cotrim, Cotrim D.s., Sulmeprim, Sulmeprim Pediatric, Sulfatrim-ss, Sulfatrim-ds, Uroplus Ss, Uroplus Ds, Trimeth/sulfa.

On Jan, 29, 2015: 28,160 people who reported to have side effects when taking Bactrim are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pyrexia (fever)Pyrexia (fever)Anaemia (lack of blood)Nausea (feeling of having an urge to vomit)Lactic Acidosis (low ph in body tissues)Anaemia (lack of blood)Hypertension Nos (high blood pressure)Pain
Nausea (feeling of having an urge to vomit)Neutropenia (an abnormally low number of neutrophils)Thrombocytopenia (decrease of platelets in blood)DeathRenal Failure Acute (rapid kidney dysfunction)Weight DecreasedHiv Wasting Syndrome (aids wasting syndrome occurs when you have aids and lose at least 10% of your body weight -- especially muscle)Pyrexia (fever)
Rash (redness)Anaemia (lack of blood)Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)DiarrhoeaDiarrhoeaAsthenia (weakness)Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Nausea (feeling of having an urge to vomit)
Renal Failure Acute (rapid kidney dysfunction)DiarrhoeaNeutropenia (an abnormally low number of neutrophils)DizzinessDehydration (dryness resulting from the removal of water)Liver Function Test AbnormalRenal Failure Acute (rapid kidney dysfunction)Anxiety
Stevens-johnson Syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)Renal Impairment (severely reduced kidney function)Anaemia (lack of blood)Hyperkalaemia (damage to or disease of the kidney)Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)Urinary Tract Infection NosVomiting
DiarrhoeaThrombocytopenia (decrease of platelets in blood)Renal Failure Acute (rapid kidney dysfunction)Weight DecreasedMalaise (a feeling of general discomfort or uneasiness)Pulmonary Embolism (blockage of the main artery of the lung)Dehydration (dryness resulting from the removal of water)Dyspnoea (difficult or laboured respiration)
VomitingVomitingCytomegalovirus InfectionVomitingNausea (feeling of having an urge to vomit)Pyrexia (fever)Diarrhoea NosDiarrhoea
Thrombocytopenia (decrease of platelets in blood)Sepsis (a severe blood infection that can lead to organ failure and death)Septic Shock (shock due to blood infection)Dehydration (dryness resulting from the removal of water)Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)Nausea (feeling of having an urge to vomit)Fatigue (feeling of tiredness)Anaemia (lack of blood)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Pyrexia (fever)Renal Failure Acute (rapid kidney dysfunction)Headache (pain in head)Abdominal PainVomiting NosFatigue (feeling of tiredness)
Alanine Aminotransferase IncreasedNausea (feeling of having an urge to vomit)Toxic Epidermal Necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)DepressionVomitingPyrexia (fever)Pneumonia

Most common side effects by age * :

Maternal Drugs Affecting Foetus (chemical affecting the baby before birth taken by mother)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)Pyrexia (fever)
Blood Lactic Acid IncreasedNeutropenia (an abnormally low number of neutrophils)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Renal Failure Acute (rapid kidney dysfunction)
Blood Creatine Phosphokinase IncreasedAspartate Aminotransferase IncreasedVomitingVomitingRenal Failure Acute (rapid kidney dysfunction)Renal Failure Acute (rapid kidney dysfunction)Thrombocytopenia (decrease of platelets in blood)Nausea (feeling of having an urge to vomit)
Neutropenia Neonatal (an abnormally low number of neutrophils in below a month baby)VomitingAnxietyPainFatigue (feeling of tiredness)PainRenal Failure Acute (rapid kidney dysfunction)Asthenia (weakness)
Hypertriglyceridaemia (excess of triglycerides in the blood)Alanine Aminotransferase IncreasedHeadache (pain in head)Fatigue (feeling of tiredness)DiarrhoeaAsthenia (weakness)DiarrhoeaDyspnoea (difficult or laboured respiration)
Neutropenia (an abnormally low number of neutrophils)DiarrhoeaFatigue (feeling of tiredness)Abdominal PainThrombocytopenia (decrease of platelets in blood)Anaemia (lack of blood)Dyspnoea (difficult or laboured respiration)Thrombocytopenia (decrease of platelets in blood)
Neonatal Disorder Nos (disease of neonates)CoughHypotension (abnormally low blood pressure)Headache (pain in head)Blood Creatinine IncreasedFatigue (feeling of tiredness)Blood Creatinine IncreasedPain
Anaemia NeonatalTachycardia (a heart rate that exceeds the range of 100 beats/min)DepressionPulmonary Embolism (blockage of the main artery of the lung)VomitingDiarrhoeaVomitingFatigue (feeling of tiredness)
Pyrexia (fever)Haemoglobin DecreasedDyspnoea (difficult or laboured respiration)Pain In ExtremityAsthenia (weakness)Weight DecreasedAnaemia (lack of blood)Anaemia (lack of blood)
Neonatal Disorder (disease of neonates)Thrombocytopenia (decrease of platelets in blood)Arthralgia (joint pain)DiarrhoeaCondition AggravatedVomitingFatigue (feeling of tiredness)Pneumonia

* Some reports may have incomplete information.

Browse Bactrim side effects from A to Z:

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Are you taking Bactrim?

Comments from related studies:

  • From this study (6 days ago):

  • Developed rash from head to toes. Very severe and itchy.


  • From this study (4 weeks ago):

  • i had shingles 1 year ago and i also have gastritis, h pylori hernias from gallbladder operation and i am so so bloated i cant breathe


  • From this study (1 month ago):

  • I have this issue every single time I take Bactrim or Septra... This time the pain is excruciating and I am so uncomfortable.


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Can you answer these questions (Ask a question):

  • Can i use a lidocaine patch for back pain if i am taking prograf for anti-rejection post lung transplant?
    Transplant was 6 years ago.
    Has suffered from PTLD on several occasions before.
    Recently hospitalized for Periodic Fever Syndrome.
    Received Interleukin 6 blocker last week and fevers have resolved, but back pain is still present
  • Can bactrim ds treat shingle?
    I am wondering can Bactrim DS treat shingles? Because l am HIV POSITIVE my specialist prescribed me Bactrim DS and Atripla, and l realise Bactrim DS is an antiviral tablets that is why l like to know whether l can use Bactrim DS to treat shingles. This is the second times l have shingles. Please help me!
  • Can sulfamethoxazole-tmp ds, raise or lower blood sugar. (1 answer)
    Symptoms the last 10 days are chills, sweating, light fever (98.9 to 100) sometimes. General malaise, tired, poor sleep. Just depressed, because of the recurrent Infection that no antibiotics (supposedly the bacteria Klesiella-pneumoniae is Sensitive to all the antibiotics I have taken so far)has cleared this stuborn condition.
  • How long did the hives/itching eyes last?
    had back to back allergic reactions to iv abx - after clinda (april 2014) developed sjs - still having hives around my eyes, watering, and severe itching. have been on 4x dose zyrtec, prn benadryl. when will this go away?
  • What can i do about nausea from generic bactrim (1 answer)
    I want to know what I can do to combat nausea from this drug

More questions for: Bactrim

You may be interested at these reviews (Write a review):

  • Bactrim-hypopigmentation, nausea, other side effects
    Took bactrim for 7 days 2x a day, was told to take for 14 days. Had persistent and worsening nausea, vomiting, fatigue, hypopigmentation of my skin when I sat in the sun for over 5 minutes, inability to fall asleep, headache, and neck pain. Ended up with low iron and folic acid levels, which were treated with supplements and discontinuation of the Bactrim resolved symptoms.
  • Uti symptoms for woman
    I had the tingling and dumbness in my feet for weeks until I went to doctor, I had ATI after antibiotic nothing.

  • Bactrim causes severe side effects (1 response)
    I get bladder infections on a regular basis. I do not have a doctor so I end up in the ER every time. I normally go to the same ER but not all the time. I have been prescribed medications like Cipro and Bactrim. Cipro usually knocks out the infection but I always get another one.
    For the last three years Doctors have been prescribing me Bactrim. In the last two months I had three bladder infections and took Bactrim for ten days seven and three. I didn't realize the medications themselves would harm me as well. Now I have severe abdominal pain every single day. I did some research on Bactrim and discovered it can cause several different kinds of stomach problems. I have been in pain for two months straight non-stop.
    I finally discovered that the Bactrim killed both the good and bad bacteria in my body and now my digestive system is off balance. I went to a natural food store and bought some probiotics. It helped relieve some stomach pain after four days, but if I forget to take it one time it comes back. I think something is wrong with me but not exactly sure what. When I get a doctor next month I will update this article.
    I just want to say that Bactrim has severe side effects, I DO NOT recommend taking this drug. Cipro is better in the long run.
  • Something should be done....
    Medicine had my kness aching badly. Cause my legs to lock up where I couldn't bend then. Had to elevate for 2weeks. Feeling better but they still hurt and knees keep popping. Had to take fluid pills cause they were so swollen.
  • Interaction between bactrim & vit c
    I drank one tablet of bactrim with glass of vit C (1 tablet), after 5 minutes I became red (face & eyes) with high tachycardia and high pressure in the ears.

    After 15 minutes I observed differents red points on the skin (hand, arms & legs).

    I would like to inform you that I took in the past bactrim and vit C but separately, never both in the same moment.

    I was afraid to have an internal emoragy, I provoked the vomiting to eliminate everything in my stomach.

    Affer 10 minutes the situation became normal and pressure returned normal.

    I took 1 tablet of antistaminc for allergy and the red points eliminated.

More reviews for: Bactrim

On eHealthMe, Bactrim (sulfamethoxazole; trimethoprim) is often used for urinary tract infection. Find out below the conditions Bactrim is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Bactrim used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Bactrim drug interactions:

Browse Bactrim drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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