How effective is Lyrica for Bipolar disorder?
Summary: 4 Lyrica users have rated its effectiveness for Bipolar disorder.
Overall ratings: 2.8/5
This is a review of how effective Lyrica (pregabalin) is for Bipolar disorder and for what kind of people. The study is created by eHealthMe and is updated continuously.
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What is Lyrica
Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 66,558 users)
Bipolar disorder (mood disorder) can be treated by Lamictal, Lithium Carbonate, Abilify, Seroquel, Lamotrigine, Depakote. (latest reports from Bipolar Disorder 43,640 patients)
On Dec, 22, 2014: 4 people are studied for taking Lyrica in Bipolar disorder
Lyrica effectiveness for Bipolar disorder (number of people):
|not at all||somewhat||moderate||high||very high |
Gender of people who take Lyrica for Bipolar disorder * :
|Bipolar disorder||100.00%||0.00% |
Age of people who take Lyrica for Bipolar disorder * :
|Bipolar disorder||0.00%||0.00%||0.00%||50.00%||25.00%||25.00%||0.00%||0.00% |
Who find Lyrica more effective for Bipolar disorder?
Gender of people who find Lyrica more effective * :
|Bipolar disorder||100.00%||0.00% |
Age of people who find Lyrica more effective * :
|Bipolar disorder||0.00%||0.00%||0.00%||0.00%||100.00%||0.00%||0.00%||0.00% |
* Approximation only. Some reports may have incomplete information.
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More questions for: Lyrica, Bipolar disorder
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- Leg pain especially near knees after taking lyrica
Had to stop taking Lyrica due to joint pain in both legs. Difficult to get up from sitting position to stand. Ache in knee's can't relax to sleep. Motrin and vicodin not helping with pain. Also have applied muscle cream not working for pain. Have been off the lyrica for 3 months with no let up in pain. Did not have this pain before taking lyrica.
- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
- Restless leg syndrome exasporation while on lovastatim.
I have been taking Lovastatin for 4 months and have had an increase in my Restless Leg Syndrome. It usually acts up in the afternoon when I'm relaxing. The symptoms seem to go away with rhythmic movement of the affected leg. Usually it is in only one leg at a time. I have also noted a fine tremors in my hands. I consider this as a recurring of the RLS because I have had this before beginning Lovastatin, but it had pretty much abated since then. My doctor back then started me on Amantadine and it worked well.
- Bipolar patient extremely violent on seraquel
I have been diagnosed bipolar for over 10 years. 3 years ago I was taken off of topamax and my seraquel was upped to 300 mg from 100 because I was pregnant. I was very violent! Punching, breaking stuff, in jail, in the psych ward. Yes pregnancy and bipolar are not a perfect combination. I too thought it was the hormones. My husband and split several times over me punching him. We moved to a state cross country so there was no more family drama. Nothing worked! Over the last 3 years my life has been hell! I happen to run out of my seroquel (tg) it took 2 weeks to arrive. In that time my body went thru horrible withdrawals. I vowed I wouldn't take it any longer. I've been seraquel free for 2 months. I'm now on gabapentin and proud to say I have no anger issues! Not 1 punch has
been thrown. I feel like a totally different person.
- Nexium improves my constipation
Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
More reviews for: Lyrica, Bipolar disorder
Comments from related studies:
From this study (4 years ago):
The month I started Lyrica... a few days or short week(s) after I was diagnosed with herpes. It shocked me and I was hoping to find a possible connection, but I might be out of luck. =/
From this study (4 years ago):
Lately I have MAJOR loss of cordination, pain shooting up from my hands to my elbows.... I am falling and tripping, unable to keep my balance. I am sick to my stomach all of the time. I throw up any solid foods. I have the runs, and major suicidal behaviours, I have been writing my goodbye letters to my family, saving up my pills, as well as buying more off of the street in order to kill myself. I cry constantly and would rather pee myself than crawl out of bed... What is wrong with me? I need help. Nothing but hopelessness and pain is all I feel inside my head and throughout my body... someone help me.... My mom just gave me some Lyrica hoping that I can replace my lamictal with that and that it will help me not feel like this I am leaving this trying to get more information
Jay Smith on Jun, 29, 2010:
you are a total mess...climb the Texas Tower and let it rip without a chute?
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