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Zyrtec vs Claritin vs Allegra, a side effect and effectiveness comparison for a female patient aged 50

This is personalized comparison of Zyrtec vs Claritin vs Allegra for a female aged 50. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Zyrtec (latest outcomes from 29,909 users) has active ingredients of cetirizine hydrochloride. It is often used in allergen.

Claritin (latest outcomes from 24,172 users) has active ingredients of loratadine. It is often used in allergen.

Allegra (latest outcomes from 23,830 users) has active ingredients of fexofenadine hydrochloride. It is often used in allergies.

What is the symptom

Irritability (latest reports from 146,707 patients) has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder.

On Jul, 6, 2014: 10,001 female patients aged 48 who take the same drugs are studied in Zyrtec vs Claritin vs Allegra

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Zyrtec cetirizine hydrochlorideMcneil Consumer
Claritin loratadineSchering Plough
Allegra fexofenadine hydrochlorideSanofi Aventis Us

eHealthMe real world results:

For females aged 48 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Zyrtec (Mcneil Consumer)Claritin (Schering Plough)Allegra (Sanofi Aventis Us)

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zyrtec (Mcneil Consumer)Claritin (Schering Plough)Allegra (Sanofi Aventis Us)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Headache (pain in head)Chest PainChest Pain
Drug IneffectiveFatigue (feeling of tiredness)Headache (pain in head)
Fatigue (feeling of tiredness)Drug IneffectiveDyspnoea (difficult or laboured respiration)
DizzinessDepressionFatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)Headache (pain in head)Dizziness
Chest PainPalpitations (feelings or sensations that your heart is pounding or racing)Drug Ineffective
Pruritus (severe itching of the skin)Dyspnoea (difficult or laboured respiration)Depression
DepressionDizzinessArthralgia (joint pain)
Weight IncreasedArthralgia (joint pain)Anxiety

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zyrtec (Mcneil Consumer)Claritin (Schering Plough)Allegra (Sanofi Aventis Us)
Headache (pain in head)Acute Myocardial Infarction (acute heart attack)Weight Gain
DepressionDyspepsia (indigestion)Constipation
VertigoTachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)Heat Intolerance (feeling of being overheated)
AnxietyTricuspid Valve Incompetence (inefficient heart valve)Weakness
Vertigo - Positional (disorder arising in the inner ear cause vertigo)Weight IncreasedMottled Skin (a condition in which the skin becomes discoloured in irregular patches)
Insomnia (sleeplessness)Arteriospasm Coronary (spasm of the large- or medium-sized coronary arteries)Skin Burning Sensation
Urticaria (rash of round, red welts on the skin that itch intensely)Mitral Valve Incompetence (inefficient heart valve)Hair Loss
Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)Sacroiliitis (an inflammation of the sacroiliac joint)Oedema Peripheral (superficial swelling)
Fatigue (feeling of tiredness)Intervertebral Disc DisplacementPain In Extremity
Deafness UnilateralFatigue (feeling of tiredness)Dry Mouth

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study:
1. print a copy of the study
and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Zyrtec (cetirizine hydrochloride) is often used to treat allergen. Claritin (loratadine) is often used to treat allergen. Allegra (fexofenadine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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