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Home > Health tools > Drug comparison > Dimenhydrinate vs Meclizine vs Diphenhydramine Hydrochloride

Dimenhydrinate vs Meclizine vs Diphenhydramine Hydrochloride, a side effect and effectiveness comparison for a female patient aged 59

This is personalized comparison of Dimenhydrinate vs Meclizine vs Diphenhydramine Hydrochloride for a female aged 59. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Dimenhydrinate (latest outcomes from 1,030 users) has active ingredients of dimenhydrinate. It is often used in nausea.

Meclizine (latest outcomes from 5,831 users) has active ingredients of meclizine hydrochloride. It is often used in dizziness.

Diphenhydramine hydrochloride (latest outcomes from 2,993 users) has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia.

On Oct, 13, 2014: 4,416 female patients aged 57 who take the same drugs are studied in Dimenhydrinate vs Meclizine vs Diphenhydramine Hydrochloride

Information of patient in study:

GenderAgeReason for the drug
Female57Motion Sickness

Drugs to compare:

DrugIngredientsCompany
Dimenhydrinate dimenhydrinatenot specified
Meclizine meclizine hydrochloridenot specified
Diphenhydramine Hydrochloride diphenhydramine hydrochloridenot specified

eHealthMe real world results:

For females aged 57 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
DimenhydrinateMeclizineDiphenhydramine Hydrochloride
Back PainDizzinessNausea (feeling of having an urge to vomit)
Condition AggravatedNausea (feeling of having an urge to vomit)Dyspnoea (difficult or laboured respiration)
DiarrhoeaVertigoPruritus (severe itching of the skin)
Nausea (feeling of having an urge to vomit)Chest PainPyrexia (fever)
Haemoglobin DecreasedAsthenia (weakness)Vomiting
Pyrexia (fever)Dyspnoea (difficult or laboured respiration)Chest Pain
DepressionFatigue (feeling of tiredness)Headache (pain in head)
Neutropenia (an abnormally low number of neutrophils)FallPain
Ascites (accumulation of fluid in the abdominal cavity)AnxietyDizziness
Herpes ZosterHeadache (pain in head)Anxiety

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
DimenhydrinateMeclizineDiphenhydramine Hydrochloride
DiarrheaDepressionExhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)
ItchinessHigh Blood CholesterolRash (redness)
Anal Candidiasis (rectal fungal infection)Gerd (gastro-oesophageal reflux disease)Flushing (the warm, red condition of human skin)
Urinary Frequency AggravatedVertigoInsomnia Exacerbated (sleeplessness)
Gouty Arthritis (joint inflammation with crystal formation)Migraine (headache)Sweating Fever (fever with sweating)
Irritable Bowel Syndrome AggravatedHigh Blood PressureNausea (feeling of having an urge to vomit)
Nausea Aggravated (feeling of having an urge to vomit)Thyroiditis (inflammation of thyroid gland)Hair Loss
External Ear PainMs (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)Fatigue (feeling of tiredness)
Blepharitis (chronic inflammation of the eyelid)AnxietyLow Blood Pressure (abnormally low blood pressure)
Headaches (pain in head)Vertigo-associated DisordersAnger

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Dimenhydrinate0.00%21.74%21.74%43.48%13.04%
Meclizine0.00%27.50%35.00%25.00%12.50%
Diphenhydramine Hydrochloride1.19%25.00%32.14%31.75%9.92%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Dimenhydrinate (dimenhydrinate) is often used to treat nausea. Meclizine (meclizine hydrochloride) is often used to treat dizziness. Diphenhydramine Hydrochloride (diphenhydramine hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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