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Home > Health tools > Drug comparison > Cymbalta vs Wellbutrin

Cymbalta vs Wellbutrin, a side effect and effectiveness comparison for a female patient aged 42

This is personalized comparison of Cymbalta vs Wellbutrin for a female aged 42. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Cymbalta (latest outcomes from 49,259 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Wellbutrin (latest outcomes from 54,950 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

On Oct, 26, 2014: 14,688 female patients aged 40 who take the same drugs are studied in Cymbalta vs Wellbutrin

Information of patient in study:

GenderAgeReason for the drug
Female40Pain

Drugs to compare:

DrugIngredientsCompany
Cymbalta duloxetine hydrochloridenot specified
Wellbutrin bupropion hydrochloridenot specified

eHealthMe real world results:

For females aged 40 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
CymbaltaWellbutrin
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
DizzinessInsomnia (sleeplessness)
Headache (pain in head)Depression
Fatigue (feeling of tiredness)Headache (pain in head)
DepressionDizziness
Insomnia (sleeplessness)Fatigue (feeling of tiredness)
Weight IncreasedDrug Ineffective
PainAnxiety
Feeling AbnormalWeight Increased
Suicidal IdeationChest Pain

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
CymbaltaWellbutrin
Nausea (feeling of having an urge to vomit)Insomnia (sleeplessness)
DizzinessConstipation
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Migraine (headache)
Headache (pain in head)Dizziness
DepressionDry Mouth
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry)
Suicidal IdeationChronic Fatigue Syndrome (disorder that causes extreme fatigue)
Fatigue (feeling of tiredness)Acne Cystic (skin problems that cause pimples)
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)Chronic Sinusitis (long lasting inflammation of the paranasal sinuses)
Weight IncreasedMeniere's Disease Aggravated (a disorder of the inner ear that can affect hearing and balance to a varying degree)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Cymbalta5.05%24.44%36.26%23.43%10.81%
Wellbutrin3.04%22.75%34.21%32.32%7.68%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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