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Piroxicam vs Celecoxib vs Naproxen vs Mefenamic Acid vs Ibuprofen, a side effect and effectiveness comparison for a male patient aged 32

This is personalized comparison of Piroxicam vs Celecoxib vs Naproxen vs Mefenamic Acid vs Ibuprofen for a male aged 32. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Piroxicam (latest outcomes from 3,094 users) has active ingredients of piroxicam. It is often used in arthritis.

Celecoxib (latest outcomes from 9,286 users) has active ingredients of celecoxib. It is often used in osteoarthritis.

Naproxen (latest outcomes from 21,914 users) has active ingredients of naproxen. It is often used in pain.

Mefenamic acid (latest outcomes from 1,145 users) has active ingredients of mefenamic acid. It is often used in painful menstrual periods.

Ibuprofen (latest outcomes from 61,569 users) has active ingredients of ibuprofen. It is often used in pain.

What is the symptom

Hepatocellular damage (liver damage) (latest reports from 30,699 patients) has been reported by people with high blood cholesterol, rheumatoid arthritis, depression, arthritis, pain.

On Oct, 25, 2014: 3,083 male patients aged 30 who take the same drugs are studied in Piroxicam vs Celecoxib vs Naproxen vs Mefenamic Acid vs Ibuprofen

Information of patient in study:

GenderAgeReason for the drug
Male30Inflammatory Pain

Drugs to compare:

Piroxicam piroxicamMutual Pharm
Celecoxib celecoxibnot specified
Naproxen naproxenSandoz
Mefenamic Acid mefenamic acidnot specified
Ibuprofen ibuprofennot specified

eHealthMe real world results:

For males aged 30 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Piroxicam (Mutual Pharm)CelecoxibNaproxen (Sandoz)Mefenamic AcidIbuprofen
Hepatocellular Damage13.64%0.80%0.50%0.00%1.34%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Piroxicam (Mutual Pharm)CelecoxibNaproxen (Sandoz)Mefenamic AcidIbuprofen
Pyrexia (fever)Arthralgia (joint pain)Fatigue (feeling of tiredness)Diarrhoea NosPyrexia (fever)
Lymphadenopathy (disease or enlargement of lymph nodes)Back PainAnxietyPruritus (severe itching of the skin)Nausea (feeling of having an urge to vomit)
Dysphagia (condition in which swallowing is difficult or painful)Nausea (feeling of having an urge to vomit)Headache (pain in head)Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)Vomiting
Headache (pain in head)Pain In ExtremityNausea (feeling of having an urge to vomit)Colitis Haemorrhagic (bleeding diarrhoea due to infection of colon)Depression
Leukocytosis (increased white blood cells)PainPyrexia (fever)Alanine Aminotransferase IncreasedAgitation (state of anxiety or nervous excitement)
Hepatocellular Damage (liver damage)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Insomnia (sleeplessness)Vomiting NosFatigue (feeling of tiredness)
Haematemesis (vomiting of blood)Chest PainSuicidal IdeationAspartate Aminotransferase IncreasedHeadache (pain in head)
Dermatitis Nos (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)DepressionPyrexia (fever)Renal Failure Acute (rapid kidney dysfunction)
Abdominal Pain UpperAnxietyBack PainRenal Failure Acute (rapid kidney dysfunction)Suicidal Ideation
Hypersensitivity NosVomitingDyspnoea Nos (difficult or laboured respiration)Hepatic Failure (liver failure)Completed Suicide (act of taking one's own life)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Piroxicam (Mutual Pharm)CelecoxibNaproxen (Sandoz)Mefenamic AcidIbuprofen
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)DepressionFatigue (feeling of tiredness)
DepressionInsomnia (sleeplessness)Depression
Chest PainBipolar Disorder (mood disorder)Urinary Retention (the inability to completely or partially empty the bladder)
Pulmonary Embolism (blockage of the main artery of the lung)AnxietyVentricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Hypertension (high blood pressure)AggressionAcute Myocardial Infarction (acute heart attack)
PneumoniaMental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)Gastritis (inflammation of stomach)
Intervertebral Disc Protrusion (spinal disc protrusion)Nervous System Disorder (a general class of medical conditions affecting the nervous system)Hypercholesterolaemia (high levels of cholesterol in the blood)
Acute Myocardial Infarction (acute heart attack)PsychosisEmotional Distress
Muscle Spasms (muscle contraction)Personality ChangeGastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Ventricular Fibrillation (abnormally irregular heart rhythm)Pain - KneeHypotension (abnormally low blood pressure)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Mefenamic Acid0.00%0.00%0.00%100.00%0.00%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Piroxicam (piroxicam) is often used to treat arthritis. Celecoxib (celecoxib) is often used to treat osteoarthritis. Naproxen (naproxen) is often used to treat pain. Mefenamic Acid (mefenamic acid) is often used to treat painful menstrual periods. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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