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Lipitor vs Vytorin, a side effect and effectiveness comparison for a male patient aged 55

This is personalized comparison of Lipitor vs Vytorin for a male aged 55. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Lipitor (latest outcomes from 132,675 users) has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol.

Vytorin (latest outcomes from 13,514 users) has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol.

What are the symptoms

Chest pain (latest reports from 928,051 patients) has been reported by people with high blood pressure, osteoporosis, pain, multiple sclerosis, rheumatoid arthritis.

Weight increased (latest reports from 527,968 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

On Sep, 1, 2014: 10,571 male patients aged 50 who take the same drugs are studied in Lipitor vs Vytorin

Information of patient in study:

GenderAgeReason for the drug
Male50Hyperlipdemia

Drugs to compare:

DrugIngredientsCompany
Lipitor atorvastatin calciumPfizer
Vytorin ezetimibe; simvastatinMsp Singapore

eHealthMe real world results:

For males aged 50 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Lipitor (Pfizer)Vytorin (Msp Singapore)
Chest Pain12.82%9.02%
Weight Increased4.72%4.33%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Lipitor (Pfizer)Vytorin (Msp Singapore)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chest PainNausea (feeling of having an urge to vomit)
Myalgia (muscle pain)Pain
Fatigue (feeling of tiredness)Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)Dizziness
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)Headache (pain in head)
Dyspnoea (difficult or laboured respiration)Cardiac Failure Congestive
Asthenia (weakness)Myalgia (muscle pain)
Drug IneffectiveDyspnoea (difficult or laboured respiration)
DizzinessDepression

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Lipitor (Pfizer)Vytorin (Msp Singapore)
Myalgia (muscle pain)Tendonitis (a condition that causes pain and swelling of tendons)
Blood Creatine Phosphokinase IncreasedDeath
Fatigue (feeling of tiredness)Muscular Weakness (muscle weakness)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Muscle Spasms (muscle contraction)
Asthenia (weakness)Metastases To Liver (cancer spreads to liver)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic)
DepressionBlood Creatine Phosphokinase Increased
Hypertension (high blood pressure)Taste Loss
PainNausea (feeling of having an urge to vomit)
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)Muscle Atrophy (a decrease in the mass of the muscle)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Lipitor4.43%10.16%26.56%43.75%15.10%
Vytorin0.00%4.92%21.31%50.82%22.95%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Side effects in real world:

On eHealthMe, Lipitor (atorvastatin calcium) is often used to treat high blood cholesterol. Vytorin (ezetimibe; simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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