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Related topic: High blood pressure, Hydrochlorothiazide, Spironolactone

Hydrochlorothiazide vs Spironolactone, a side effect and effectiveness comparison for a male patient aged 51

This is personalized comparison of Hydrochlorothiazide vs Spironolactone for a male aged 51. The study is created by eHealthMe based on reports from FDA and social media.

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On Apr, 10, 2014: 3,808 male patients aged 46 who take the drugs are studied in Hydrochlorothiazide vs Spironolactone

Information of patient in study:

GenderAgeReason for the drug
Male46High blood pressure

Drugs to compare:

DrugIngredientsCompany
Hydrochlorothiazide hydrochlorothiazideVintage Pharms
Spironolactone spironolactoneActavis Elizabeth

eHealthMe real world results:

For males aged 46 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Hydrochlorothiazide (Vintage Pharms)Spironolactone (Actavis Elizabeth)
Fatigue (feeling of tiredness)Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)Oedema Peripheral (superficial swelling)
Asthenia (weakness)Hypotension (abnormally low blood pressure)
Chest PainNausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)
DizzinessAscites (accumulation of fluid in the abdominal cavity)
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Vomiting
DepressionWeight Increased
PainDizziness
Oedema Peripheral (superficial swelling)Renal Failure Acute (rapid kidney dysfunction)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Hydrochlorothiazide (Vintage Pharms)Spironolactone (Actavis Elizabeth)
Lightheadedness - Dizzy (a common and often unpleasant sensation of dizziness)Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Acid Reflux (stomach acids rise up)Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
Burning Feet Syndrome (burning sensation in the sole of the foot)Renal Impairment (severely reduced kidney function)
Gout (uric acid crystals building up in the body)Blood Albumin Decreased
Sinus Congestion (blockage of sinus)Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Renal Failure Acute (rapid kidney dysfunction)Renal Failure Acute (rapid kidney dysfunction)
Loss Of ConsciousnessEncephalopathy (functioning of the brain is affected by some agent or condition)
Myalgia (muscle pain)Hepatorenal Syndrome (renal failure in patients with advanced chronic liver disease)
Myopathy (a muscular disease in which the muscle fibres do not function)Depression
Myositis (inflammation of the muscles)Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Hydrochlorothiazide3.51%21.93%48.25%19.30%7.02%
Spironolactone0.00%27.59%48.28%20.69%3.45%

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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Hydrochlorothiazide (hydrochlorothiazide) is often used to treat high blood pressure. Spironolactone (spironolactone) is often used to treat acne. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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