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Pamelor vs Zoloft for a male patient aged 30

Summary: 2,013 male patients aged 30 (±5) who take the same drugs are studied.

This is personalized comparison of Pamelor vs Zoloft for a male aged 30. The study is created by eHealthMe based on reports from FDA and social media.


What are the drugs

Pamelor (latest outcomes from 2,199 users) has active ingredients of nortriptyline hydrochloride. It is often used in migraine.

Zoloft (latest outcomes from 78,398 users) has active ingredients of sertraline hydrochloride. It is often used in depression.

What are the symptoms

Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity) has been reported by people with depression, high blood pressure, high blood cholesterol, pain, hair loss. (latest reports from 32,156 Sexual dysfunction patients)

Depression aggravated (latest reports from 260,097 Depression aggravated patients)

Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis. (latest reports from 200,917 Fatigue patients)

Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle) has been reported by people with high blood pressure, depression, multiple myeloma, osteoporosis, stress and anxiety. (latest reports from 4,179 Bundle branch block right patients)

On Mar, 8, 2015: 2,013 male patients aged 25 who take the same drugs are studied in Pamelor vs Zoloft

Information of patient in study:

GenderAgeReason for the drug
Male25Chronic depression

Drugs to compare:

Pamelor nortriptyline hydrochloridenot specified
Zoloft sertraline hydrochloridenot specified

eHealthMe real world results:

For males aged 25 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Sexual Dysfunction6.90%4.13%
Depression Aggravated3.45%6.34%
Bundle Branch Block Right0.00%0.00%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Drug IneffectiveNausea (feeling of having an urge to vomit)
Completed Suicide (act of taking one's own life)Drug Ineffective
Respiratory Depression (respiration has a rate below 12 breaths)Depression
Hypoaesthesia (reduced sense of touch or sensation)Suicidal Ideation
Heart Rate IncreasedInsomnia (sleeplessness)
Cardio-respiratory Arrest (sudden dysfunction of heart and lungs)Anxiety
Intentional OverdoseSuicide Attempt
Accidental OverdoseDizziness
Drug AbuserAgitation (state of anxiety or nervous excitement)
PainWeight Increased

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Suicide Attempt
Insomnia (sleeplessness)
Tremor (trembling or shaking movements in one or more parts of your body)
Panic Reaction
Blood Triglycerides Increased
Thrombocytopenia (decrease of platelets in blood)

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You




Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Pamelor (nortriptyline hydrochloride) is often used to treat migraine. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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