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Activella vs Prempro, a side effect and effectiveness comparison for a female patient aged 56

This is personalized comparison of Activella vs Prempro for a female aged 56. The study is created by eHealthMe based on reports from FDA and social media.

For patients like me, how are my drugs? On eHealthMe, you can research 300 million drug outcomes from FDA and social media. We use data reported since 1977 till to date. All studies are personalized to gender and age. Start now >>>

On Jan, 29, 2014: 11,056 people are studied in Activella vs Prempro

Information of patient in study:

GenderAgeReason for the drug
Female52Menopause

Drugs to compare:

DrugIngredientsCompany
Activella estradiol; norethindrone acetateNovo Nordisk Inc
Prempro estrogens, conjugated; medroxyprogesterone acetateWyeth Pharms Inc

eHealthMe real world results:

For females aged 52 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Anal Cancer0.00%0.00%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Hot Flush (sudden feelings of heat)Breast Cancer Metastatic
MastectomyNausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
DepressionDepression
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Oestrogen Receptor Assay Positive
Insomnia (sleeplessness)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
AnxietyDrug Ineffective

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Breast Cancer In SituBreast Cancer Metastatic
RadiotherapyOestrogen Receptor Assay Positive
PainProgesterone Receptor Assay Positive
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Depression
MastectomyBreast Cancer In Situ
BiopsyCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Mammogram Abnormal (abnormal breast examination)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hot Flush (sudden feelings of heat)Anxiety

For people in general (regardless of gender or age):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Anal Cancer0.00%0.00%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Hot Flush (sudden feelings of heat)Breast Cancer Metastatic
MastectomyNausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
DepressionDepression
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Oestrogen Receptor Assay Positive
Insomnia (sleeplessness)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
AnxietyDeep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
DizzinessDrug Ineffective

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Breast Cancer In SituBreast Cancer Metastatic
RadiotherapyOestrogen Receptor Assay Positive
PainProgesterone Receptor Assay Positive
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Depression
MastectomyBreast Cancer In Situ
BiopsyCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fatigue (feeling of tiredness)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hot Flush (sudden feelings of heat)Anxiety

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

If the study doesn't answer your question, you can:

Related topic: Activella, Menopause, Prempro

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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Activella (estradiol; norethindrone acetate) is often used to treat hormone replacement therapy. Prempro (estrogens, conjugated; medroxyprogesterone acetate) is often used to treat menopause. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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