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Activella vs Prempro, a side effect and effectiveness comparison for a female patient aged 56

This is personalized comparison of Activella vs Prempro for a female aged 56. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Activella (latest outcomes from 1,279 users) has active ingredients of estradiol; norethindrone acetate. It is often used in hormone replacement therapy.

Prempro (latest outcomes from 37,627 users) has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause.

What is the symptom

Anal Cancer (latest reports from 1,796 patients) has been reported by people with crohn's disease, hiv infection, osteoporosis, rheumatoid arthritis, high blood pressure.

On May, 12, 2014: 11,068 female patients aged 52 who take the same drugs are studied in Activella vs Prempro

Information of patient in study:

GenderAgeReason for the drug
Female52Menopause

Drugs to compare:

DrugIngredientsCompany
Activella estradiol; norethindrone acetateNovo Nordisk Inc
Prempro estrogens, conjugated; medroxyprogesterone acetateWyeth Pharms Inc

eHealthMe real world results:

For females aged 52 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Anal Cancer0.00%0.00%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Hot Flush (sudden feelings of heat)Breast Cancer Metastatic
Fatigue (feeling of tiredness)Nausea (feeling of having an urge to vomit)
DepressionCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Depression
Insomnia (sleeplessness)Oestrogen Receptor Assay Positive
AnxietyMyocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
DizzinessDrug Ineffective

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Activella (Novo Nordisk Inc)Prempro (Wyeth Pharms Inc)
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Breast Cancer In SituBreast Cancer Metastatic
PainOestrogen Receptor Assay Positive
Breast Mass (localized swelling that feels different from the surrounding breast tissue)Progesterone Receptor Assay Positive
Mammogram Abnormal (abnormal breast examination)Depression
Hot Flush (sudden feelings of heat)Breast Cancer In Situ
Fatigue (feeling of tiredness)Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Arthralgia (joint pain)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
DepressionAnxiety

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Activella2.00%22.00%42.00%20.00%14.00%
Prempro0.00%14.49%34.78%39.13%11.59%

How to use the study:
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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Activella (estradiol; norethindrone acetate) is often used to treat hormone replacement therapy. Prempro (estrogens, conjugated; medroxyprogesterone acetate) is often used to treat menopause. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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Related conditions

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Related drug side effects

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