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Advair Diskus 250/50 vs Singulair, a side effect and effectiveness comparison for a male patient aged 54

This is personalized comparison of Advair Diskus 250/50 vs Singulair for a male aged 54. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Advair diskus 250/50 (latest outcomes from 2,297 users) has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma.

Singulair (latest outcomes from 42,869 users) has active ingredients of montelukast sodium. It is often used in asthma.

What is the symptom

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) has been reported by people with pain, depression, high blood pressure, multiple myeloma, multiple sclerosis.(latest reports from Mental status changes 14,041 patients)

On Oct, 31, 2014: 2,930 male patients aged 50 who take the same drugs are studied in Advair Diskus 250/50 vs Singulair

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Advair Diskus 250/50 fluticasone propionate; salmeterol xinafoateGlaxosmithkline
Singulair montelukast sodiumMerck

eHealthMe real world results:

For males aged 50 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Advair Diskus 250/50 (Glaxosmithkline)Singulair (Merck)
Mental Status Changes0.81%1.06%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Advair Diskus 250/50 (Glaxosmithkline)Singulair (Merck)
Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)
Drug IneffectiveAllergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)
Chest PainFatigue (feeling of tiredness)
AnxietyNausea (feeling of having an urge to vomit)
CoughHeadache (pain in head)
Nausea (feeling of having an urge to vomit)Dizziness
Fatigue (feeling of tiredness)Chest Pain
Weight DecreasedDrug Ineffective

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Advair Diskus 250/50 (Glaxosmithkline)Singulair (Merck)
AsthmaAllergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct)
Dyspnoea (difficult or laboured respiration)Mononeuritis (single nerve damage)
Drug IneffectiveArthralgia (joint pain)
Loss Of ConsciousnessMyalgia (muscle pain)
Pyrexia (fever)Suicidal Ideation
Muscle Spasms (muscle contraction)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Status Asthmaticus (a asthma attack not responds to regular medicines)Eosinophilia (eosinophil count in the peripheral blood exceeds)
DisabilitySinusitis Nos (inflammation of sinus)
Lung Hyperinflation (inspiration of more than normal)Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)Weakness

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Advair Diskus 250/505.45%18.18%27.27%36.36%12.73%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Side effects in real world:

On eHealthMe, Advair Diskus 250/50 (fluticasone propionate; salmeterol xinafoate) is often used to treat asthma. Singulair (montelukast sodium) is often used to treat asthma. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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