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Home > Personalized tools > Drug comparison > Bactrim vs Macrobid

Bactrim vs Macrobid, a side effect and effectiveness comparison for a female patient aged 53

This is personalized comparison of Bactrim vs Macrobid for a female aged 53. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Bactrim (latest outcomes from 29,446 users) has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection.

Macrobid (latest outcomes from 3,438 users) has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection.

What is the symptom

Stomach Discomfort (pain in abdomen) (latest reports from 35,090 patients) has been reported by people with type 2 diabetes, osteoporosis, depression, high blood pressure, high blood cholesterol.

On Jul, 24, 2014: 2,930 female patients aged 48 who take the same drugs are studied in Bactrim vs Macrobid

Information of patient in study:

GenderAgeReason for the drug
Female48Bladder Infection

Drugs to compare:

DrugIngredientsCompany
Bactrim sulfamethoxazole; trimethoprimnot specified
Macrobid nitrofurantoin; nitrofurantoin, macrocrystallinenot specified

eHealthMe real world results:

For females aged 48 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

BactrimMacrobid
Stomach Discomfort0.17%1.24%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
BactrimMacrobid
Pyrexia (fever)Nausea (feeling of having an urge to vomit)
Nausea (feeling of having an urge to vomit)Chest Pain
Headache (pain in head)Urinary Tract Infection
VomitingAsthenia (weakness)
Asthenia (weakness)Headache (pain in head)
Chest PainFatigue (feeling of tiredness)
DiarrhoeaPyrexia (fever)
Anaemia (lack of blood)Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)Cough
Arthralgia (joint pain)Oedema Peripheral (superficial swelling)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
BactrimMacrobid
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)Lung Disorder (lung disease)
ConstipationDrug Toxicity
Anaemia (lack of blood)Transaminases Increased
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Respiratory Distress (difficulty in breathing)
Urine AbnormalityNeuropathy Peripheral (surface nerve damage)
DiarrhoeaOrganising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Lactic Acidosis (low ph in body tissues)Liver Disorder (liver diseases)
Renal Failure Acute (rapid kidney dysfunction)Impaired Work Ability
Hyperkalaemia (damage to or disease of the kidney)Hypoxia (low oxygen conditions)
Herpes Simplex (herpes simplex is a common viral infection)Dyspnoea Exertional (breathlessness or shortness of breath)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Bactrim8.05%37.93%20.69%22.99%10.34%
Macrobid13.04%30.43%30.43%17.39%8.70%

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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Bactrim (sulfamethoxazole; trimethoprim) is often used to treat urinary tract infection. Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) is often used to treat urinary tract infection. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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