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Home > Health tools > Drug comparison > Benadryl vs Ambien

Benadryl vs Ambien, a side effect and effectiveness comparison for a female patient aged 55

This is personalized comparison of Benadryl vs Ambien for a female aged 55. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Ambien (latest outcomes from 46,715 users) has active ingredients of zolpidem tartrate. It is often used in insomnia.

On Oct, 28, 2014: 10,756 female patients aged 50 who take the same drugs are studied in Benadryl vs Ambien

Information of patient in study:

GenderAgeReason for the drug
Female50Rash

Drugs to compare:

DrugIngredientsCompany
Benadryl diphenhydramine hydrochlorideMcneil Cons
Ambien zolpidem tartrateSanofi Aventis Us

eHealthMe real world results:

For females aged 50 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Benadryl (Mcneil Cons)Ambien (Sanofi Aventis Us)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)Anxiety
Pruritus (severe itching of the skin)Pain
Fatigue (feeling of tiredness)Fatigue (feeling of tiredness)
Headache (pain in head)Depression
AnxietyInsomnia (sleeplessness)
PainHeadache (pain in head)
Chest PainDyspnoea (difficult or laboured respiration)
DizzinessDrug Ineffective
Pyrexia (fever)Asthenia (weakness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Benadryl (Mcneil Cons)Ambien (Sanofi Aventis Us)
Ringing In The Ears (a ringing in the ears)Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Flushing (the warm, red condition of human skin)Fatigue (feeling of tiredness)
VomitingDepression
Insomnia Exacerbated (sleeplessness)Anxiety
WeaknessTremor (trembling or shaking movements in one or more parts of your body)
DizzinessAbnormal Sleep-related Event
DiarrheaSomnambulism (sleep walking)
Dermatitis Lichen Planus-like (well-defined area of a purple-coloured itchy rash)Hypertension (high blood pressure)
Fatigue (feeling of tiredness)Sleep Walking (walking during sleep)
Insomnia (sleeplessness)Nausea (feeling of having an urge to vomit)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Benadryl1.07%22.46%36.36%29.95%10.16%
Ambien2.41%15.00%32.96%33.70%15.93%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Ambien (zolpidem tartrate) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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