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Doxycycline Hyclate vs Minocycline Hydrochloride, a side effect and effectiveness comparison for a male patient aged 69

This is personalized comparison of Doxycycline Hyclate vs Minocycline Hydrochloride for a male aged 69. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Doxycycline hyclate (latest outcomes from 2,387 users) has active ingredients of doxycycline hyclate. It is often used in acne.

Minocycline hydrochloride (latest outcomes from 1,797 users) has active ingredients of minocycline hydrochloride. It is often used in acne.

On Aug, 13, 2014: 1,118 male patients aged 64 who take the same drugs are studied in Doxycycline Hyclate vs Minocycline Hydrochloride

Information of patient in study:

GenderAgeReason for the drug
Male64Prostatitis - chronic

Drugs to compare:

Doxycycline Hyclate doxycycline hyclateWatson Labs
Minocycline Hydrochloride minocycline hydrochlorideTriax Pharms

eHealthMe real world results:

For males aged 64 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Doxycycline Hyclate (Watson Labs)Minocycline Hydrochloride (Triax Pharms)

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Doxycycline Hyclate (Watson Labs)Minocycline Hydrochloride (Triax Pharms)
Dyspnoea (difficult or laboured respiration)Pyrexia (fever)
PainCondition Aggravated
AnxietyPneumonia Nos
Nausea (feeling of having an urge to vomit)Disseminated Intravascular Coagulation (systemic activation of blood coagulation)
Renal Failure Acute (rapid kidney dysfunction)Pneumonia
InjuryInterstitial Lung Disease
PneumoniaMethicillin-resistant Staphylococcal Aureus Infection
Anaemia (lack of blood)C-reactive Protein Increased
Pain In JawPleural Effusion (water on the lungs)
Bone DisorderThrombocytopenia (decrease of platelets in blood)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Doxycycline Hyclate (Watson Labs)Minocycline Hydrochloride (Triax Pharms)
Sebaceous Carcinoma (cancer tumour of oil gland of skin)Oral Candidiasis (fungal infection of mouth)
Subdural Hematoma (blood collects between the skull and the surface of the brain)Pericarditis (inflammation of the pericardium)
Polyneuropathy Nos (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)Oesophagitis (inflammation of oesophagus)
Sweating DecreasedMycobacterium Avium Complex Infection
Sudden Hearing LossJoint Stiffness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Keratitis Herpetic (inflammation of the cornea due to infection of a present or previous herpes simplex virus)
Heat Exhaustion (dizziness and nausea and weakness caused by depletion of body fluids and electrolytes)Prostatic Specific Antigen Increased
Lack Of Strength, Muscle Weakness, WeaknessPulmonary Mass
Exercise Tolerance DecreasedMyalgia (muscle pain)
Stomach Discomfort (pain in abdomen)Screaming (a long loud piercing cry)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Doxycycline Hyclate6.67%33.33%33.33%26.67%0.00%
Minocycline Hydrochloride0.00%20.00%30.00%50.00%0.00%

How to use the study:
1. print a copy of the study
and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Alternative drugs:

Side effects in real world:

On eHealthMe, Doxycycline Hyclate (doxycycline hyclate) is often used to treat acne. Minocycline Hydrochloride (minocycline hydrochloride) is often used to treat acne. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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