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Enbrel vs Arava, a side effect and effectiveness comparison for a female patient aged 47

This is personalized comparison of Enbrel vs Arava for a female aged 47. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Enbrel (latest outcomes from 175,509 users) has active ingredients of etanercept. It is often used in rheumatoid arthritis.

Arava (latest outcomes from 16,322 users) has active ingredients of leflunomide. It is often used in rheumatoid arthritis.

On Aug, 15, 2014: 9,616 female patients aged 42 who take the same drugs are studied in Enbrel vs Arava

Information of patient in study:

GenderAgeReason for the drug
Female42Rheumatoid Arthritis

Drugs to compare:

Enbrel etanerceptImmunex
Arava leflunomideSanofi Aventis Us

eHealthMe real world results:

For females aged 42 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Enbrel (Immunex)Arava (Sanofi Aventis Us)
Injection Site PainNausea (feeling of having an urge to vomit)
Injection Site Erythema (redness at injection site)Alanine Aminotransferase Increased
Injection Site Reaction NosDrug Exposure During Pregnancy
Injection Site SwellingAspartate Aminotransferase Increased
Injection Site Haemorrhage (bleeding from injection site)Pyrexia (fever)
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)Headache (pain in head)
Injection Site Haematoma (localized swelling filled with blood at injection site)Injection Site Erythema (redness at injection site)
Injection Site Pruritus (severe itching at injection site)Injection Site Pain
Nausea (feeling of having an urge to vomit)Injection Site Reaction Nos
Arthralgia (joint pain)Fatigue (feeling of tiredness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Enbrel (Immunex)Arava (Sanofi Aventis Us)
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)Alanine Aminotransferase Increased
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)Drug Exposure During Pregnancy
Hypoaesthesia (reduced sense of touch or sensation)Aspartate Aminotransferase Increased
Condition AggravatedAbortion Spontaneous (naturally occurring miscarriage)
Drug IneffectiveAsthenia (weakness)
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)Maternal Drugs Affecting Foetus (chemical affecting the baby before birth taken by mother)
Arthralgia (joint pain)Complications Of Maternal Exposure To Therapeutic Drugs
Breast CancerLiver Function Test Abnormal
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Hallucinations, Mixed (sensations that appear real but are created by your mind -mixed)
CoughLegionella Infection (a lung infection caused by bacteria of the species legionella)

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Enbrel (etanercept) is often used to treat rheumatoid arthritis. Arava (leflunomide) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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