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Flexeril vs Zanaflex, a side effect and effectiveness comparison for a female patient aged 42

This is personalized comparison of Flexeril vs Zanaflex for a female aged 42. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Flexeril (latest outcomes from 16,423 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Zanaflex (latest outcomes from 7,294 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

On Sep, 10, 2014: 3,554 female patients aged 37 who take the same drugs are studied in Flexeril vs Zanaflex

Information of patient in study:

GenderAgeReason for the drug
Female37Muscle Spasms

Drugs to compare:

DrugIngredientsCompany
Flexeril cyclobenzaprine hydrochlorideMcneil Ped
Zanaflex tizanidine hydrochlorideAcorda

eHealthMe real world results:

For females aged 37 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Flexeril (Mcneil Ped)Zanaflex (Acorda)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Chest PainHeadache (pain in head)
Headache (pain in head)Pain
DepressionFatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)Asthenia (weakness)
Weight IncreasedCondition Aggravated
Fatigue (feeling of tiredness)Dizziness
DizzinessChest Pain
Arthralgia (joint pain)Pyrexia (fever)
AnxietyMultiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Flexeril (Mcneil Ped)Zanaflex (Acorda)
Memory ImpairmentHead Injury
Fatigue (feeling of tiredness)Basilar Migraine (migraine with neurological symptoms related to the brain stem or with neurological symptoms on both sides of the body)
DizzinessOccipital Neuralgia (condition characterized by chronic pain in the upper neck)
Muscle Weakness (a lack of muscle strength)Insomnia (sleeplessness)
ConfusionStomach Pain
Tremor (trembling or shaking movements in one or more parts of your body)Hallucinations (sensations that appear real but are created by your mind)
Nausea (feeling of having an urge to vomit)Constipation
Mood Swings (an extreme or rapid change in mood)Fatigue (feeling of tiredness)
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Alanine Aminotransferase Increased
Thyroid Disorder (thyroid diseases)Aspartate Aminotransferase Increased

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Flexeril7.67%35.00%38.67%16.00%2.67%
Zanaflex4.72%24.41%37.80%25.20%7.87%

How to use the study:
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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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