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Home > Personalized tools > Drug comparison > Flexeril vs Zanaflex

Flexeril vs Zanaflex, a side effect and effectiveness comparison for a female patient aged 42

This is personalized comparison of Flexeril vs Zanaflex for a female aged 42. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Flexeril (latest outcomes from 16,436 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Zanaflex (latest outcomes from 7,301 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

On Oct, 13, 2014: 3,566 female patients aged 37 who take the same drugs are studied in Flexeril vs Zanaflex

Information of patient in study:

GenderAgeReason for the drug
Female37Muscle Spasms

Drugs to compare:

DrugIngredientsCompany
Flexeril cyclobenzaprine hydrochlorideMcneil Ped
Zanaflex tizanidine hydrochlorideAcorda

eHealthMe real world results:

For females aged 37 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Flexeril (Mcneil Ped)Zanaflex (Acorda)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Chest PainHeadache (pain in head)
Headache (pain in head)Pain
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
DepressionAsthenia (weakness)
Weight IncreasedCondition Aggravated
Fatigue (feeling of tiredness)Dizziness
Arthralgia (joint pain)Chest Pain
DizzinessPyrexia (fever)
AnxietyVomiting

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Flexeril (Mcneil Ped)Zanaflex (Acorda)
Memory ImpairmentInsomnia (sleeplessness)
DizzinessBasilar Migraine (migraine with neurological symptoms related to the brain stem or with neurological symptoms on both sides of the body)
Fatigue (feeling of tiredness)Fever
ConfusionOccipital Neuralgia (condition characterized by chronic pain in the upper neck)
Muscle Weakness (a lack of muscle strength)Abdominal Pain
Tremor (trembling or shaking movements in one or more parts of your body)Head Injury
Nausea (feeling of having an urge to vomit)Diarrhoea Post-operative
Muscle TwitchingReflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile)
Loss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And Numbness (unusual prickling sensations)Joint Stiffness
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)Migraine (headache)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Flexeril7.64%34.88%38.54%16.28%2.66%
Zanaflex4.55%23.48%36.36%27.27%8.33%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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