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Home > Health tools > Drug comparison > Keppra vs Depakote Er

Keppra vs Depakote Er, a side effect and effectiveness comparison for a female patient aged 62

This is personalized comparison of Keppra vs Depakote Er for a female aged 62. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Keppra (latest outcomes from 21,204 users) has active ingredients of levetiracetam. It is often used in epilepsy.

Depakote er (latest outcomes from 3,677 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.

What is the symptom

Agitation (state of anxiety or nervous excitement) (latest reports from 54,307 patients) has been reported by people with depression, quit smoking, pain, stress and anxiety, high blood pressure.

On Oct, 30, 2014: 3,350 female patients aged 57 who take the same drugs are studied in Keppra vs Depakote Er

Information of patient in study:

GenderAgeReason for the drug
Female57Myoclonic Seizure Nos

Drugs to compare:

DrugIngredientsCompany
Keppra levetiracetamUcb Inc
Depakote Er divalproex sodiumAbbott

eHealthMe real world results:

For females aged 57 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Keppra (Ucb Inc)Depakote Er (Abbott)
Agitation2.72%6.29%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Keppra (Ucb Inc)Depakote Er (Abbott)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Nausea (feeling of having an urge to vomit)
Nausea (feeling of having an urge to vomit)Weight Increased
Fatigue (feeling of tiredness)Fall
FallDizziness
DizzinessHeadache (pain in head)
Thrombocytopenia (decrease of platelets in blood)Depression
Headache (pain in head)Drug Ineffective
Asthenia (weakness)Tremor (trembling or shaking movements in one or more parts of your body)
Hypotension (abnormally low blood pressure)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Confusional StateInsomnia (sleeplessness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Keppra (Ucb Inc)Depakote Er (Abbott)
Myalgia (muscle pain)Weight Decreased
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Oedema Peripheral (superficial swelling)
DepressionHeadache (pain in head)
Memory LossCellulitis (infection under the skin)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Itching
Complex Partial Seizures Exacerbated (epileptic seizure)Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Varicose Veins (veins that have become enlarged and tortuous)Bacterial Arthritis (infectious arthritis)
Short-term Memory LossLaryngeal Nerve Damage
Bleeding Time ProlongedAsthenia (weakness)
Tremor (trembling or shaking movements in one or more parts of your body)Vitamin D Decreased

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Keppra3.61%14.46%21.69%38.55%21.69%
Depakote Er2.60%12.99%32.47%36.36%15.58%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Side effects in real world:

On eHealthMe, Keppra (levetiracetam) is often used to treat epilepsy. Depakote Er (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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