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Lyrica vs Cymbalta, a side effect and effectiveness comparison for a female patient aged 53

This is personalized comparison of Lyrica vs Cymbalta for a female aged 53. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Lyrica (latest outcomes from 66,459 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

Cymbalta (latest outcomes from 49,102 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

What are the symptoms

Weight Gain (latest reports from 527,106 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

Weight Gain (latest reports from 527,106 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

On Apr, 27, 2014: 11,466 female patients aged 49 who take the drugs are studied in Lyrica vs Cymbalta

Information of patient in study:

GenderAgeReason for the drug
Female49Fibromyalgia

Drugs to compare:

DrugIngredientsCompany
Lyrica pregabalinCp Pharms
Cymbalta duloxetine hydrochlorideLilly

eHealthMe real world results:

For females aged 49 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Lyrica (Cp Pharms)Cymbalta (Lilly)
Weight Gain11.19%4.64%
Weight Gain11.19%4.64%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Lyrica (Cp Pharms)Cymbalta (Lilly)
Weight IncreasedNausea (feeling of having an urge to vomit)
DizzinessDizziness
PainHeadache (pain in head)
Somnolence (a state of near-sleep, a strong desire for sleep)Depression
Drug IneffectiveFatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)Pain
Oedema Peripheral (superficial swelling)Anxiety
Headache (pain in head)Insomnia (sleeplessness)
Vision BlurredFeeling Abnormal
Feeling AbnormalWeight Increased

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Lyrica (Cp Pharms)Cymbalta (Lilly)
Vision BlurredSinus Headache (headache caused by sinus infections)
PainSore Throat (pain or irritation of the throat)
Weight IncreasedNausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)Dizziness
Oedema Peripheral (superficial swelling)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
DepressionParaesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Headache (pain in head)
DizzinessDepression
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Visual Acuity Reduced (reduced clearness of vision)Weight Increased

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Lyrica7.77%27.43%36.65%21.12%7.04%
Cymbalta3.65%26.80%38.77%24.29%6.50%

How to use the study:
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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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- Fibromyalgia
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