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Home > Health tools > Drug comparison > Nexium vs Omeprazole

Nexium vs Omeprazole, a side effect and effectiveness comparison for a male patient aged 69

This is personalized comparison of Nexium vs Omeprazole for a male aged 69. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Nexium (latest outcomes from 73,123 users) has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease.

Omeprazole (latest outcomes from 92,763 users) has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease.

What is the symptom

Abdominal pain (latest reports from 106,123 patients) has been reported by people with birth control, crohn's disease, high blood pressure, pain, depression.

On Sep, 3, 2014: 14,869 male patients aged 65 who take the same drugs are studied in Nexium vs Omeprazole

Information of patient in study:

GenderAgeReason for the drug
Male65GERD

Drugs to compare:

DrugIngredientsCompany
Nexium esomeprazole magnesiumAstrazeneca
Omeprazole omeprazoleDexcel Pharma

eHealthMe real world results:

For males aged 65 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Nexium (Astrazeneca)Omeprazole (Dexcel Pharma)
Abdominal Pain6.35%4.69%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Nexium (Astrazeneca)Omeprazole (Dexcel Pharma)
Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)Pyrexia (fever)
PainNausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
AnxietyFatigue (feeling of tiredness)
DiarrhoeaHypotension (abnormally low blood pressure)
PneumoniaAsthenia (weakness)
Asthenia (weakness)Chest Pain
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Renal Failure Acute (rapid kidney dysfunction)
Chest PainAnaemia (lack of blood)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Nexium (Astrazeneca)Omeprazole (Dexcel Pharma)
Nausea (feeling of having an urge to vomit)Depression
Pyrexia (fever)Arrhythmia (irregular heartbeat)
DizzinessFibromyalgia (a long-term condition which causes pain all over the body)
AnxietyHerpes Simplex Antibody Positive
Erectile DysfunctionDizziness
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)Tinnitus (a ringing in the ears)
Malaise (a feeling of general discomfort or uneasiness)Chest Pain
Thrombocytopenia (decrease of platelets in blood)Dizziness Aggravated
Renal Failure (kidney dysfunction)Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nephritis Interstitial (a kidney condition characterized by swelling in between the kidney tubules)Swollen Tongue (swelling of tongue)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Nexium1.02%5.61%24.49%41.84%27.04%
Omeprazole1.90%11.18%21.10%48.31%17.51%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Nexium (esomeprazole magnesium) is often used to treat gastroesophageal reflux disease. Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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