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Phenergan vs Benadryl, a side effect and effectiveness comparison for a female patient aged 51

This is personalized comparison of Phenergan vs Benadryl for a female aged 51. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Phenergan (latest outcomes from 13,014 users) has active ingredients of promethazine hydrochloride. It is often used in nausea.

Benadryl (latest outcomes from 29,335 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

On Aug, 13, 2014: 4,889 female patients aged 47 who take the same drugs are studied in Phenergan vs Benadryl

Information of patient in study:

GenderAgeReason for the drug
Female47Nausea

Drugs to compare:

DrugIngredientsCompany
Phenergan promethazine hydrochloridenot specified
Benadryl diphenhydramine hydrochlorideMcneil Cons

eHealthMe real world results:

For females aged 47 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
VomitingDyspnoea (difficult or laboured respiration)
PainHeadache (pain in head)
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Chest PainPain
AnxietyPyrexia (fever)
Headache (pain in head)Chest Pain
Dehydration (dryness resulting from the removal of water)Pruritus (severe itching of the skin)
Back PainAnxiety
Abdominal PainVomiting

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Anxiety AggravatedArthritis (form of joint disorder that involves inflammation of one or more joints)
Heart Rate IncreasedPseudoporphyria (skin changes consistent with one of the porphyrias, but laboratory tests do not detect significant abnormalities)
Insomnia (sleeplessness)Anxiety
Nausea (feeling of having an urge to vomit)Depression
VomitingFacial Nerve Disorder (disease of face nerve)
Sweating Increased (excess sweating)Fatigue - Chronic (long feeling of tiredness)
Fatigue (feeling of tiredness)Facial Pain
Nausea And VomitingConstipation
Muscle Aches (muscle pain)Memory Loss
Tachycardia Irregular (irregular, uneven, or skipping beats with increased heart rate)Pelvic Discomfort

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Phenergan4.72%8.66%37.80%21.26%27.56%
Benadryl1.42%27.49%31.75%27.01%12.32%

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Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Phenergan (promethazine hydrochloride) is often used to treat nausea. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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