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Phenergan vs Benadryl, a side effect and effectiveness comparison for a female patient aged 51

This is personalized comparison of Phenergan vs Benadryl for a female aged 51. The study is created by eHealthMe based on reports from FDA and social media.

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On Feb, 3, 2014: 4,811 people are studied in Phenergan vs Benadryl

Information of patient in study:

GenderAgeReason for the drug
Female47Nausea

Drugs to compare:

DrugIngredientsCompany
Phenergan promethazine hydrochloridenot specified
Benadryl diphenhydramine hydrochlorideMcneil Cons

eHealthMe real world results:

For females aged 47 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
VomitingDyspnoea (difficult or laboured respiration)
PainHeadache (pain in head)
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Chest PainPain
AnxietyPyrexia (fever)
Headache (pain in head)Chest Pain
Dehydration (dryness resulting from the removal of water)Pruritus (severe itching of the skin)
Back PainAnxiety
Abdominal PainVomiting

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Nausea (feeling of having an urge to vomit)Arthritis (form of joint disorder that involves inflammation of one or more joints)
Can Not Sweat, Therefore I Have No Cooling System. I Get Heat Exhaustion Often. Throsing Up Goose Bumps Purple Face Etc.Pseudoporphyria (skin changes consistent with one of the porphyrias, but laboratory tests do not detect significant abnormalities)
Numbness And Tingling (unusual prickling sensations)Pelvic Discomfort
Abdominal Pain AggravatedAnxiety
Muscle TwitchingHerniated Intervertebral Disk
Fecal Incontinence (inability to control stool)Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry)
Bile Duct Pressure IncreasedFacial Nerve Disorder (disease of face nerve)
Muscle Aches (muscle pain)Trigeminal Nerve Injection
Tachycardia Irregular (irregular, uneven, or skipping beats with increased heart rate)Depression Suicidal (suicide depressive disorder)
Migraine (headache)Depression

For people in general (regardless of gender or age):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
VomitingDyspnoea (difficult or laboured respiration)
PainHeadache (pain in head)
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Chest PainPain
AnxietyPyrexia (fever)
Headache (pain in head)Chest Pain
Dehydration (dryness resulting from the removal of water)Pruritus (severe itching of the skin)
Back PainAnxiety
Abdominal PainVomiting

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
PhenerganBenadryl (Mcneil Cons)
Nausea (feeling of having an urge to vomit)Pseudoporphyria (skin changes consistent with one of the porphyrias, but laboratory tests do not detect significant abnormalities)
Can Not Sweat, Therefore I Have No Cooling System. I Get Heat Exhaustion Often. Throsing Up Goose Bumps Purple Face Etc.Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fatigue (feeling of tiredness)Pelvic Discomfort
Abdominal DistensionAnxiety
Fecal Incontinence (inability to control stool)Herniated Intervertebral Disk
Weight DecreasedAnxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry)
Anemia - Hemolytic (anaemia due to haemolysis, the abnormal breakdown of red blood cells (rbcs), either in the blood vessels (intravascular haemolysis) or elsewhere in the human body (extra vascular))Depression Suicidal (suicide depressive disorder)
Spasms In Right Upper TrapeziusFacial Nerve Palsy (paralysis of face nerve)
Hair LossFacial Pain
Bile Duct Pressure IncreasedMemory Loss

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Nausea, Phenergan

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Phenergan (promethazine hydrochloride) is often used to treat nausea. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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