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Home > Health tools > Drug comparison > Premarin vs Ogen .625

Premarin vs Ogen .625, a side effect and effectiveness comparison for a female patient aged 63

This is personalized comparison of Premarin vs Ogen .625 for a female aged 63. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Premarin (latest outcomes from 70,314 users) has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy.

Ogen .625 (latest outcomes from 12 users) has active ingredients of estropipate.

On Oct, 29, 2014: 22,373 female patients aged 58 who take the same drugs are studied in Premarin vs Ogen .625

Information of patient in study:

GenderAgeReason for the drug
Female58post hysterectomy

Drugs to compare:

Premarin estrogens, conjugatedWyeth Pharms Inc
Ogen .625 estropipatenot specified

eHealthMe real world results:

For females aged 58 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Premarin (Wyeth Pharms Inc)Ogen .625
Breast CancerBreast Cancer
Breast Cancer FemaleBreast Cancer Female
Nausea (feeling of having an urge to vomit)Breast Cancer Metastatic
Breast Cancer MetastaticOestrogen Receptor Assay Positive
Chest PainNausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)Anxiety
DepressionProgesterone Receptor Assay Positive
Drug IneffectiveDepression
AnxietyFatigue (feeling of tiredness)
Asthenia (weakness)Asthenia (weakness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Premarin (Wyeth Pharms Inc)Ogen .625
Breast Cancer FemaleBreast Cancer Female
Breast CancerBreast Cancer
Oestrogen Receptor Assay PositiveOestrogen Receptor Assay Positive
Progesterone Receptor Assay PositiveProgesterone Receptor Assay Positive
Breast Cancer MetastaticBreast Cancer Metastatic
DepressionMetastases To Bone (cancer spreads to bone)
Breast Cancer In SituBreast Cancer In Situ
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Hepatic Steatosis (fatty liver disease)
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)Tumour Necrosis (death of tumour tissues)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Ogen .6250.00%0.00%50.00%50.00%0.00%

Comments from or about the patient:

I have taken ogen for 10 years post hysterectomy. My dr. suggested a smaller dose of estrogen so thought premarin .o3 would be better. Ogen has worked well in the past. I'd like to know the difference between the two drugs.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Side effects in real world:

On eHealthMe, Premarin (estrogens, conjugated) is often used to treat hormone replacement therapy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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