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Home > Health tools > Drug comparison > Prometrium vs Norethindrone Acetate

Prometrium vs Norethindrone Acetate, a side effect and effectiveness comparison for a female patient aged 52

This is personalized comparison of Prometrium vs Norethindrone Acetate for a female aged 52. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Prometrium (latest outcomes from 3,631 users) has active ingredients of progesterone. It is often used in menopause.

Norethindrone acetate (latest outcomes from 220 users) has active ingredients of norethindrone acetate. It is often used in bleeding.

On Oct, 13, 2014: 1,616 female patients aged 47 who take the same drugs are studied in Prometrium vs Norethindrone Acetate

Information of patient in study:

GenderAgeReason for the drug
Female47Bleeding between periods

Drugs to compare:

Prometrium progesteroneUnimed Pharms
Norethindrone Acetate norethindrone acetateBarr

eHealthMe real world results:

For females aged 47 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Prometrium (Unimed Pharms)Norethindrone Acetate (Barr)
Nausea (feeling of having an urge to vomit)Breast Cancer
Fatigue (feeling of tiredness)Pain In Extremity
Breast CancerDrug Ineffective
AnxietyOedema Peripheral (superficial swelling)
Pruritus (severe itching of the skin)Chest Pain
Arthralgia (joint pain)Anxiety
Weight IncreasedNausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)Fatigue (feeling of tiredness)
Asthenia (weakness)Depression
Back PainInsomnia (sleeplessness)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Prometrium (Unimed Pharms)Norethindrone Acetate (Barr)
Breast CancerBreast Cancer
Breast Cancer FemaleMyocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Arthritis (form of joint disorder that involves inflammation of one or more joints)Breast Cancer Female
Arthralgia (joint pain)Oestrogen Receptor Assay Positive
Fatigue (feeling of tiredness)Meniscus Lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Biopsy Breast AbnormalProgesterone Receptor Assay Positive
Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills)Soft Tissue Disorder (disease of soft tissue)
Oestrogen Receptor Assay PositiveOvarian Cancer (cancer of ovary)
AnxietyRetinopathy Proliferative (condition in which very small blood vessels grow from the surface of the retina and damages retina)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)Retinal Detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Norethindrone Acetate7.14%7.14%64.29%21.43%0.00%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Prometrium (progesterone) is often used to treat menopause. Norethindrone Acetate (norethindrone acetate) is often used to treat bleeding. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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