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Home > Health tools > Drug comparison > Simponi vs Enbrel

Simponi vs Enbrel, a side effect and effectiveness comparison for a female patient aged 45

This is personalized comparison of Simponi vs Enbrel for a female aged 45. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Simponi (latest outcomes from 2,794 users) has active ingredients of golimumab. It is often used in rheumatoid arthritis.

Enbrel (latest outcomes from 175,520 users) has active ingredients of etanercept. It is often used in rheumatoid arthritis.

On Oct, 29, 2014: 7,135 female patients aged 40 who take the same drugs are studied in Simponi vs Enbrel

Information of patient in study:

GenderAgeReason for the drug
Female40Psoriatic Arthritus

Drugs to compare:

DrugIngredientsCompany
Simponi golimumabnot specified
Enbrel etanerceptImmunex

eHealthMe real world results:

For females aged 40 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
SimponiEnbrel (Immunex)
Breast CancerInjection Site Erythema (redness at injection site)
Intervertebral Discitis (infection in the intervertebral disc space)Injection Site Pain
Pyrexia (fever)Injection Site Reaction Nos
PneumoniaInjection Site Swelling
Enterocolitis ViralInjection Site Haemorrhage (bleeding from injection site)
Headache (pain in head)Injection Site Pruritus (severe itching at injection site)
Staphylococcal Infection (an infection with staphylococcus bacteria)Injection Site Haematoma (localized swelling filled with blood at injection site)
Tuberculosis (a bacterial infection by mycobacterium tuberculosis)Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)Nausea (feeling of having an urge to vomit)
Cytomegalovirus InfectionInjection Site Warmth

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
SimponiEnbrel (Immunex)
Intervertebral Discitis (infection in the intervertebral disc space)Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Breast CancerRheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)
Neuroma (tumour of nerve tissue)Drug Ineffective
Nodule On Extremity (a small rock or mineral cluster on hands or legs)Hypoaesthesia (reduced sense of touch or sensation)
Obesity (a medical condition in which excess body fat)Condition Aggravated
Insomnia (sleeplessness)Headache (pain in head)
Joint Effusion (presence of extra fluid in joint covering)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)Fatigue (feeling of tiredness)
Menopause (end of monthly cycles in women)Arthralgia (joint pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Drug Exposure During Pregnancy

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Simponi0.00%0.00%50.00%0.00%50.00%
Enbrel2.80%14.02%24.30%29.91%28.97%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Side effects in real world:

On eHealthMe, Simponi (golimumab) is often used to treat rheumatoid arthritis. Enbrel (etanercept) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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