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Symbicort vs Spiriva vs Atrovent vs Combivent vs Advair Hfa, a side effect and effectiveness comparison for a male patient aged 73

This is personalized comparison of Symbicort vs Spiriva vs Atrovent vs Combivent vs Advair Hfa for a male aged 73. The study is created by eHealthMe based on reports from FDA and social media.

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What are the drugs

Symbicort (latest outcomes from 21,389 users) has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma.

Spiriva (latest outcomes from 50,438 users) has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease.

Atrovent (latest outcomes from 13,749 users) has active ingredients of ipratropium bromide. It is often used in asthma.

Combivent (latest outcomes from 14,544 users) has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma.

Advair hfa (latest outcomes from 6,808 users) has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma.

On Jul, 12, 2014: 10,038 male patients aged 68 who take the same drugs are studied in Symbicort vs Spiriva vs Atrovent vs Combivent vs Advair Hfa

Information of patient in study:

GenderAgeReason for the drug
Male68COPD

Drugs to compare:

DrugIngredientsCompany
Symbicort budesonide; formoterol fumarate dihydrateAstrazeneca
Spiriva tiotropium bromide monohydrateBoehringer Ingelheim
Atrovent ipratropium bromideBoehringer Ingelheim
Combivent albuterol sulfate; ipratropium bromideBoehringer Ingelheim
Advair Hfa fluticasone propionate; salmeterol xinafoateGlaxosmithkline

eHealthMe real world results:

For males aged 68 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Symbicort (Astrazeneca)Spiriva (Boehringer Ingelheim)Atrovent (Boehringer Ingelheim)Combivent (Boehringer Ingelheim)Advair Hfa (Glaxosmithkline)
Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)Dyspnoea (difficult or laboured respiration)
Drug IneffectiveDrug IneffectiveNausea (feeling of having an urge to vomit)Drug IneffectiveDrug Ineffective
PneumoniaChronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)PneumoniaPneumoniaPneumonia
CoughPneumoniaPyrexia (fever)Hypotension (abnormally low blood pressure)Asthenia (weakness)
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Asthenia (weakness)Hypotension (abnormally low blood pressure)Pyrexia (fever)Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)
Pyrexia (fever)Fatigue (feeling of tiredness)Dyspnoea Nos (difficult or laboured respiration)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Dysphonia (speech disorder attributable to a disorder of phonation)CoughCardiac Failure CongestiveAsthenia (weakness)Fatigue (feeling of tiredness)
Thrombocytopenia (decrease of platelets in blood)Oedema Peripheral (superficial swelling)Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Cough
Wheezing (a high-pitched whistling sound made while you breathe)Nausea (feeling of having an urge to vomit)Condition AggravatedCardiac Failure CongestiveHypotension (abnormally low blood pressure)
Nasopharyngitis (inflammation of the nasopharynx)Dry MouthAtrial Fibrillation (fibrillation of the muscles of the atria of the heart)Fatigue (feeling of tiredness)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Symbicort (Astrazeneca)Spiriva (Boehringer Ingelheim)Atrovent (Boehringer Ingelheim)Combivent (Boehringer Ingelheim)Advair Hfa (Glaxosmithkline)
Cholangitis (infection of the bile duct)Drug IneffectiveChest DiscomfortAccidental OverdoseVisual Acuity Reduced (reduced clearness of vision)
Pancreatic Carcinoma (pancreatic cancer)Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Completed Suicide (act of taking one's own life)Dyspnoea (difficult or laboured respiration)Cough
CoughCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Tumour Lysis Syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)Dyspnoea (difficult or laboured respiration)
Aphonia (inability to produce voice)PneumoniaTumour Flare (temporary increase in symptoms from a cancer after starting treatment)Polyuria (production of too much dilute urine)Abdominal Discomfort
Drug IneffectiveAcute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)Thrombocytopenia (decrease of platelets in blood)Drug IneffectivePhotophobia (extreme sensitivity to light)
Metastases To Liver (cancer spreads to liver)Acute Respiratory FailureRenal Failure (kidney dysfunction)Respiratory Arrest (cessation of normal respiration due to failure of the lungs to function effectively)Pneumonia
PneumoniaVision BlurredHyperkalaemia (damage to or disease of the kidney)Rash (redness)Drug Ineffective
Shortness Of BreathRenal Failure (kidney dysfunction)Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)Respiratory Failure (inadequate gas exchange by the respiratory system)Gout (uric acid crystals building up in the body)
Pyrexia (fever)Hyperhidrosis (abnormally increased sweating)Renal Failure Acute (rapid kidney dysfunction)Device FailureEye Disorder
Wheezing (a high-pitched whistling sound made while you breathe)Hypertension (high blood pressure)Oliguria (not enough urine)Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Symbicort0.00%13.04%56.52%30.43%0.00%
Spiriva4.55%21.21%40.91%28.79%4.55%
Atrovent0.00%0.00%80.00%10.00%10.00%
Combivent14.29%0.00%85.71%0.00%0.00%
Advair Hfa0.00%18.00%38.00%30.00%14.00%

How to use the study:
1. print a copy of the study
and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
2. start a mobile support group with people like you or your health teams to improve treatment outcomes together.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Symbicort (budesonide; formoterol fumarate dihydrate) is often used to treat asthma. Spiriva (tiotropium bromide monohydrate) is often used to treat chronic obstructive pulmonary disease. Atrovent (ipratropium bromide) is often used to treat asthma. Combivent (albuterol sulfate; ipratropium bromide) is often used to treat asthma. Advair Hfa (fluticasone propionate; salmeterol xinafoate) is often used to treat asthma. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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