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Topamax vs Depakote for a female patient aged 52

Summary: 6,798 female patients aged 52 (±5) who take the same drugs are studied.

This is personalized comparison of Topamax vs Depakote for a female aged 52. The study is created by eHealthMe based on reports from FDA and social media.


What are the drugs

Topamax (latest outcomes from 24,636 users) has active ingredients of topiramate. It is often used in migraine.

Depakote (latest outcomes from 30,959 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.

What is the symptom

Long-term memory loss has been reported by people with multiple sclerosis, depression, pain, high blood pressure, high blood cholesterol. (latest reports from 63,451 Long-term memory loss patients)

On Mar, 26, 2015: 6,798 female patients aged 47 who take the same drugs are studied in Topamax vs Depakote

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Topamax topiramateOrtho Mcneil Janssen
Depakote divalproex sodiumAbbott

eHealthMe real world results:

For females aged 47 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
Long-term Memory Loss3.50%2.75%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
NauseaDiabetes Mellitus
HeadacheWeight Increased
FatigueType 2 Diabetes Mellitus
Drug IneffectiveNausea
Weight DecreasedHeadache
DizzinessChest Pain
MigraineDrug Ineffective

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
FatigueWeight Increased
Diarrhoea AggravatedPyrexia
Exhaustion, Fatigue, Lethargy, Tiredness, WearinessDepression
Hair LossDiabetes Mellitus
Weight DecreasedFatigue
Dry MouthUrinary Incontinence
Bone And Joint PainRinging In The Ears

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You




Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Topamax (topiramate) is often used to treat migraine. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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