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Topamax vs Depakote, a side effect and effectiveness comparison for a female patient aged 51

This is personalized comparison of Topamax vs Depakote for a female aged 51. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Topamax (latest outcomes from 24,547 users) has active ingredients of topiramate. It is often used in migraine.

Depakote (latest outcomes from 30,921 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.

What is the symptom

Long-term memory loss (latest reports from 466,972 patients) has been reported by people with multiple sclerosis, depression, high blood pressure, pain, high blood cholesterol.

On Jul, 10, 2014: 6,724 female patients aged 47 who take the same drugs are studied in Topamax vs Depakote

Information of patient in study:

GenderAgeReason for the drug
Female47Migraine

Drugs to compare:

DrugIngredientsCompany
Topamax topiramateOrtho Mcneil Janssen
Depakote divalproex sodiumAbbott

eHealthMe real world results:

For females aged 47 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
Long-term Memory Loss3.46%2.69%

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
Nausea (feeling of having an urge to vomit)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Headache (pain in head)Weight Increased
Drug IneffectiveType 2 Diabetes Mellitus
Fatigue (feeling of tiredness)Nausea (feeling of having an urge to vomit)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Insomnia (sleeplessness)Alopecia (absence of hair from areas of the body)
Weight DecreasedHeadache (pain in head)
DepressionTremor (trembling or shaking movements in one or more parts of your body)
DizzinessDrug Ineffective
Migraine (headache)Chest Pain

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Topamax (Ortho Mcneil Janssen)Depakote (Abbott)
Fatigue (feeling of tiredness)Nausea (feeling of having an urge to vomit)
Diarrhoea AggravatedWeight Increased
Seizures (abnormal excessive or synchronous neuronal activity in the brain)Cancer - Stomach (stomach cancer)
Weight DecreasedTremor (trembling or shaking movements in one or more parts of your body)
Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Vomiting
Loss Of TasteDepression
DizzinessDiabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Loss Of SmellFatigue (feeling of tiredness)
Dry MouthUrinary Incontinence (inability to control the flow of urine and involuntary urination)
DepressionPyrexia (fever)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Topamax4.04%21.06%28.09%30.43%16.38%
Depakote0.66%21.71%36.18%23.03%18.42%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Topamax (topiramate) is often used to treat migraine. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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