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Tri-sprintec vs Loestrin 24 Fe, a side effect and effectiveness comparison for a female patient aged 27

This is personalized comparison of Tri-sprintec vs Loestrin 24 Fe for a female aged 27. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Tri-sprintec (latest outcomes from 528 users) has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control.

Loestrin 24 fe (latest outcomes from 1,144 users) has active ingredients of ethinyl estradiol; norethindrone acetate. It is often used in birth control.

On Jul, 27, 2014: 3,809 female patients aged 23 who take the same drugs are studied in Tri-sprintec vs Loestrin 24 Fe

Information of patient in study:

GenderAgeReason for the drug
Female23Birth Control

Drugs to compare:

Tri-sprintec ethinyl estradiol; norgestimateBarr
Loestrin 24 Fe ethinyl estradiol; norethindrone acetateWarner Chilcott

eHealthMe real world results:

For females aged 23 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Tri-sprintec (Barr)Loestrin 24 Fe (Warner Chilcott)
DepressionNausea (feeling of having an urge to vomit)
Nausea (feeling of having an urge to vomit)Depression
Inflammatory Bowel DiseaseDrug Exposure During Pregnancy
Headache (pain in head)Anxiety
Drug Exposure During PregnancyFatigue (feeling of tiredness)
AnxietyHeadache (pain in head)
Colitis (inflammation of colon)Colitis Ulcerative (inflammation of colon with ulcer)
Dry SkinColitis (inflammation of colon)
Crohn's Disease (condition that causes inflammation of the gastrointestinal tract)Inflammatory Bowel Disease
Fatigue (feeling of tiredness)Vomiting

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Tri-sprintec (Barr)Loestrin 24 Fe (Warner Chilcott)
AnxietyNausea (feeling of having an urge to vomit)
Nausea (feeling of having an urge to vomit)Headache (pain in head)
PainFatigue (feeling of tiredness)
Heartburn (a condition in which stomach contents leak backward from the stomach into the oesophagus)Depression
Pulmonary Embolism (blockage of the main artery of the lung)Vertigo
Drug Exposure During PregnancyDizziness
DiarrheaAbdominal Pain
Cold SweatSweating - Excessive (abnormally increased sweating)
Headache (pain in head)Menstruation Irregular

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Loestrin 24 Fe1.31%5.25%13.12%36.48%43.83%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Tri-sprintec (ethinyl estradiol; norgestimate) is often used to treat birth control. Loestrin 24 Fe (ethinyl estradiol; norethindrone acetate) is often used to treat birth control. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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