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Zantac 150 vs Pepcid Ac, a side effect and effectiveness comparison for a male patient aged 66

This is personalized comparison of Zantac 150 vs Pepcid Ac for a male aged 66. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Zantac 150 (latest outcomes from 3,892 users) has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease.

Pepcid ac (latest outcomes from 3,314 users) has active ingredients of famotidine. It is often used in gastroesophageal reflux disease.

On Oct, 25, 2014: 8,438 male patients aged 61 who take the same drugs are studied in Zantac 150 vs Pepcid Ac

Information of patient in study:

GenderAgeReason for the drug

Drugs to compare:

Zantac 150 ranitidine hydrochlorideGlaxosmithkline
Pepcid Ac famotidineMerck

eHealthMe real world results:

For males aged 61 (±5):

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zantac 150 (Glaxosmithkline)Pepcid Ac (Merck)
Pyrexia (fever)Pyrexia (fever)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)Platelet Count Decreased
Chest PainHypotension (abnormally low blood pressure)
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)Haemoglobin Decreased
Hypotension (abnormally low blood pressure)Thrombocytopenia (decrease of platelets in blood)
Asthenia (weakness)White Blood Cell Count Decreased
Fatigue (feeling of tiredness)Chest Pain
DizzinessAspartate Aminotransferase Increased
Thrombocytopenia (decrease of platelets in blood)Dyspnoea (difficult or laboured respiration)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zantac 150 (Glaxosmithkline)Pepcid Ac (Merck)
Interstitial Lung DiseaseMalaise (a feeling of general discomfort or uneasiness)
Acute Respiratory Distress Syndrome (sudden failure of the respiratory (breathing) system)Aspartate Aminotransferase Increased
DizzinessAlanine Aminotransferase Increased
Respiratory Failure (inadequate gas exchange by the respiratory system)Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)Gamma-glutamyltransferase Increased
Dystonia (abnormal muscle tone)Difficulty In Walking
DepressionRhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Stress And AnxietyBlood Lactate Dehydrogenase Increased
AngerBlood Alkaline Phosphatase Increased
Testicular Atrophy (wasting of testes)Asthenia (weakness)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Zantac 1503.33%12.22%42.22%37.78%4.44%
Pepcid Ac0.00%16.67%37.50%41.67%4.17%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Zantac 150 (ranitidine hydrochloride) is often used to treat gastroesophageal reflux disease. Pepcid Ac (famotidine) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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