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Home > Health tools > Drug comparison > Zofran vs Phenergan

Zofran vs Phenergan, a side effect and effectiveness comparison for a female patient aged 68

This is personalized comparison of Zofran vs Phenergan for a female aged 68. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Zofran (latest outcomes from 882 users) has active ingredients of ondansetron hydrochloride. It is often used in nausea.

Phenergan (latest outcomes from 13,023 users) has active ingredients of promethazine hydrochloride. It is often used in nausea.

On Oct, 25, 2014: 1,832 female patients aged 63 who take the same drugs are studied in Zofran vs Phenergan

Information of patient in study:

GenderAgeReason for the drug
Female63Nausea

Drugs to compare:

DrugIngredientsCompany
Zofran ondansetron hydrochlorideGlaxosmithkline
Phenergan promethazine hydrochlorideWyeth Pharms Inc

eHealthMe real world results:

For females aged 63 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)

Zofran (Glaxosmithkline)Phenergan (Wyeth Pharms Inc)
Phenergan

Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zofran (Glaxosmithkline)Phenergan (Wyeth Pharms Inc)
Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)
Pyrexia (fever)Vomiting
VomitingDyspnoea (difficult or laboured respiration)
Dyspnoea (difficult or laboured respiration)Back Pain
Dehydration (dryness resulting from the removal of water)Anxiety
Neutropenia (an abnormally low number of neutrophils)Dehydration (dryness resulting from the removal of water)
Anaemia (lack of blood)Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)Fall
Abdominal PainPain
Asthenia (weakness)Arthralgia (joint pain)

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Zofran (Glaxosmithkline)Phenergan (Wyeth Pharms Inc)
Dyspnoea (difficult or laboured respiration)Seizures (abnormal excessive or synchronous neuronal activity in the brain)
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)Tinnitus (a ringing in the ears)
Abdominal Pain LowerApathy
Cancer PainAsthenia (weakness)
Extrasystoles
Vomiting
Heart Rate Irregular
Dysphoria (generalized dissatisfaction with life)
Weight Gain
Night Sweats (sweating in night)

Drug effectiveness:

not at allsomewhatmoderatehighvery high
Zofran0.00%43.75%31.25%12.50%12.50%
Phenergan0.00%19.05%52.38%19.05%9.52%

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Zofran (ondansetron hydrochloride) is often used to treat nausea. Phenergan (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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