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Home > Health tools > Drug comparison > Humira vs Simponi

Humira vs Simponi, a side effect and effectiveness comparison for a female patient aged 51

This is personalized comparison of Humira vs Simponi for a female aged 51. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Humira (latest outcomes from 136,683 users) has active ingredients of adalimumab. It is often used in rheumatoid arthritis.

Simponi (latest outcomes from 2,794 users) has active ingredients of golimumab. It is often used in rheumatoid arthritis.

On Nov, 21, 2014: 7,806 female patients aged 47 who take the same drugs are studied in Humira vs Simponi

Information of patient in study:

GenderAgeReason for the drug
Female47Rheumatoid Arthritis

Drugs to compare:

Humira adalimumabnot specified
Simponi golimumabnot specified

eHealthMe real world results:

For females aged 47 (±5):

Comparison with the specified adverse outcomes:

(outcome and its % of total reports)


Most common side effects:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Injection Site PainPneumonia
Headache (pain in head)Breast Cancer
Arthralgia (joint pain)Intervertebral Discitis (infection in the intervertebral disc space)
Injection Site Erythema (redness at injection site)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug IneffectiveDeep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
PainPyrexia (fever)
Fatigue (feeling of tiredness)Chest Pain
Nausea (feeling of having an urge to vomit)Dizziness
Injection Site IrritationGeneralised Oedema (swelling all over the body)
Pyrexia (fever)Fall

Most common side effects experienced by people in long term use:

(click on each outcome to view in-depth analysis, incl. how people recovered)
Arthralgia (joint pain)Intervertebral Discitis (infection in the intervertebral disc space)
PainBreast Cancer
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)Obesity (a medical condition in which excess body fat)
Drug IneffectiveNodule On Extremity (a small rock or mineral cluster on hands or legs)
Dyspnoea (difficult or laboured respiration)Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Sinusitis (inflammation of sinus)Neuroma (tumour of nerve tissue)
Fatigue (feeling of tiredness)Menopause (end of monthly cycles in women)
Headache (pain in head)Joint Effusion (presence of extra fluid in joint covering)
Joint SwellingLipoma Excision
Abdominal PainOsteoporosis (bones weak and more likely to break)

Drug effectiveness:

not at allsomewhatmoderatehighvery high

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: study your drugs OR ask a question from Patients Like You

Drug effectiveness in real world:

Alternative drugs:

Side effects in real world:

On eHealthMe, Humira (adalimumab) is often used to treat rheumatoid arthritis. Simponi (golimumab) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug comparison:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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