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Review: could Constipation cause Intestinal perforation?

Summary: Intestinal perforation could be caused by Constipation, especially for people who are male, 60+ old, also have Pain, and take Dexamethasone.

We study 16,054 people who have Constipation from FDA and social media. Among them, 89 have Intestinal perforation (Gastrointestinal perforation). Find out below who they are, other conditions they have and drugs they take.

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Constipation

Constipation (latest reports from 506,439 patients) is typically treated by Miralax, Colace, Amitiza, Senna, Lactulose, Milk Of Magnesia.

Intestinal perforation

Intestinal perforation (complete penetration of the wall of the intestine) (latest reports from 27,484 patients) has been reported by people with crohn's disease, rheumatoid arthritis, colon cancer, high blood pressure, pain.

On Apr, 12, 2014: 16,045 people who have constipation are studied. Among them, 89 (0.55%) have Intestinal Perforation. They amount to 0.33% of all the 27,343 people who have Intestinal Perforation on eHealthMe.

Trend of Intestinal perforation in constipation reports

Gender of people who have constipation and experienced Intestinal perforation * :

FemaleMale
Intestinal perforation38.57%61.43%

Age of people who have constipation and experienced Intestinal perforation * :

0-12-910-1920-2930-3940-4950-5960+
Intestinal perforation0.00%0.00%0.00%0.00%5.97%11.94%11.19%71.64%

Severity of the symptom * :

n/a

Top co-existing conditions for these people * :

  1. Pain (68 people, 76.40%)
  2. Nausea (48 people, 53.93%)
  3. Chronic obstructive pulmonary disease (41 people, 46.07%)
  4. Productive cough (38 people, 42.70%)
  5. Sedation (36 people, 40.45%)
  6. Mucosal inflammation (36 people, 40.45%)
  7. Mouth ulceration (36 people, 40.45%)
  8. Hypertension (31 people, 34.83%)
  9. Non-small cell lung cancer (25 people, 28.09%)
  10. Prophylaxis (17 people, 19.10%)

Most common drugs used by these people * :

  1. Dexamethasone (56 people, 62.92%)
  2. Lansoprazole (54 people, 60.67%)
  3. Lactulose (49 people, 55.06%)
  4. Naproxen (40 people, 44.94%)
  5. Cisplatin (39 people, 43.82%)
  6. Senna (38 people, 42.70%)
  7. Folic acid (38 people, 42.70%)
  8. Oramorph sr (37 people, 41.57%)
  9. Ciprofloxacin (37 people, 41.57%)
  10. Zopiclone (36 people, 40.45%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Constipation, Intestinal perforation

You can also:

Common treatments for Constipation and their efficacy:

Could your drug cause it?

Comments from related studies:

  • From this study (2 weeks ago):

  • Red ears and cheeks that feel warm to the touch. BP 142/78, pulse is weak but regular. When I stand up I get slight headache and I am shakey.

    Reply

  • From this study (2 weeks ago):

  • My 3 year old gets constipated. She has been on Miralax for atleast 1 year now. This past week she had an absence seizure in her sleep. Wet the bed, head turned to left and looking upward. this lasted about 35 min. could Miralax be the reason she had a seizure.

    Reply

  • From this study (2 weeks ago):

  • I have taken Lactulose for a couple years. Just today I sudden became nauseous to the point of wanting to throw up. Then in 30 seconds it was over.

    Reply

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Related condition

- Constipation (14,971 reports)

 

Related symptom

- Intestinal Perforation

 

Related drugs

- Miralax
- Colace
- Amitiza
- Senna
- Lactulose
- Milk Of Magnesia
- Polyethylene Glycol 3350
- Bisacodyl
- Dietary Fiber
- Magnesium
- Magnesium Sulfate
- Psyllium Husk
- Sennosides
- Soluble Fiber
- Probiotics
- Magnesium Citrate
- Magnesium Oxide
- Dulcolax
- Psyllium
- Duphalac

 

 

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