Would you have Enlarged spleen (Splenomegaly) when you have Myelodysplastic syndrome?
Summary: Enlarged spleen is found among people with Myelodysplastic syndrome, especially people who are male, 60+ old, also have Iron overload, and take medication Exjade.
We study 103 people who have Enlarged spleen (Splenomegaly) and Myelodysplastic syndrome from FDA and social media. Find out below who they are, other conditions they have and drugs they take.
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Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged) (latest reports from 18,215 Myelodysplastic Syndrome patients)
Enlarged spleen (enlargement of spleen) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, hepatitis c, multiple sclerosis. (latest reports from 6,146 Enlarged spleen patients)
On Jan, 26, 2015: 103 people who have myelodysplastic syndrome and Enlarged Spleen are studied.
Gender of people who have myelodysplastic syndrome and experienced Enlarged spleen * :
|Enlarged spleen||36.36%||63.64% |
Age of people who have myelodysplastic syndrome and experienced Enlarged spleen * :
|Enlarged spleen||1.92%||0.00%||0.96%||0.00%||0.00%||0.96%||15.38%||80.77% |
Severity of the symptom * :
Top co-existing conditions for these people * :
- Iron overload (8 people, 7.77%)
- Pain (6 people, 5.83%)
- Hypertension (5 people, 4.85%)
- Idiopathic thrombocytopenic purpura (5 people, 4.85%)
- Hyperuricaemia (3 people, 2.91%)
- Prophylaxis (3 people, 2.91%)
- Dyspepsia (3 people, 2.91%)
- Clostridial infection (3 people, 2.91%)
- Diarrhoea (3 people, 2.91%)
- Hypokalaemia (3 people, 2.91%)
Most common drugs used by these people * :
- Exjade (41 people, 39.81%)
- Revlimid (28 people, 27.18%)
- Neupogen (21 people, 20.39%)
- Thalomid (16 people, 15.53%)
- Aranesp (15 people, 14.56%)
- Allopurinol (14 people, 13.59%)
- Aspirin (14 people, 13.59%)
- Lasix (13 people, 12.62%)
- Acyclovir (11 people, 10.68%)
- Hydrea (11 people, 10.68%)
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Myelodysplastic Syndrome and Enlarged Spleen?
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- support group for people who have Enlarged Spleen
Could your drug cause:
Other conditions that could cause:
Can you answer these questions (Ask a question):
- Can prolonged use of warfarin cause liver and spleen damage (1 answer)
I was on warfarin for ten years. they now found that I have cirrhosis of the liver my spleen is very enlarged can this all be caused by the prolonged use of the warfarin. Doctors giving me the run around but under my ribs is killing me and they just say take pain meds and go away
- What is the prognosis for myelodysplasia?
I've just learned i may have myelodysplasia and i'd like to know more about the possible outcomes.
- I have been diagnosed with cll and now have very enlarged tonsils. my dr wants to put me on ofatumumab (arzerra) before having tonsils removed. have others had this treatment. and what is outcome?
I have been diagnosed with CLL - an intermediate form - meaning not too severe but not so mild either. After a rash (unknown cause) treated with prednisone, followed by a sore throat, my tonsils remained enlarged to the point where I have had some difficulty swallowing. A biopsy showed that the tonsils are expressing CLL, which means the enlargement is caused by CLL and not an infection. My hematologist recommends treatment with Ofatumumab (brand name arzerra) to shrink the tonsils and then I would have an ENT remove them. The hematologist thinks that just taking predisone for a longer period of time would not fully shrink them, or if it did work, I would likely get a recurrence, so recommends this mild CLL treatment. Have others had a similar situation, and if so, what drugs were used to shrink the tonsils? Thanks in advance.
- Does clonazepam 0.5 daily cause low white blood count?
do these drugs cause high blood pressure or low wbc, low platelets, enlarged spleen, skipped heartbeats, lightheadedness, unexplained bruises?
- Causes of enlarged spleen?
22 yo pt. History positive for diverticulosus with one bout of diverticulitis, svt and slight arrhythmia, IBS, peptic ulcers, bipolar disorder type 2, and morbid obesity.
Pt. Had a scan done at the end of May to r/o diverticulitis. Scan revealed splenomegaly.
Pt. Complains of fatigue, loss of appetite, low grade fevers(with no obvious causes), and states that she has seen an increase of moles on her skin.
What should pt. Be concerned about/speak with her internist about? Any ideas?
More questions for: Myelodysplastic syndrome, Enlarged spleen
You may be interested at these reviews (Write a review):
- Why was this drug not tested for people with anemia problems?
My husband has had myelodysplastic syndrome diagnosed in 2004. In 2010, his HGB went down to 10.2. RBC 3.00. He was right next to treatment when the HGB went to 10. For some unknown reason, his blood counts improved. By June 2013, his HGB was 11.9, RBC 33.9 8/3/13 he was found to have a 75% blockage of his LAD and a stent was implanted. Brilinta was started. 11/7/13 his HGB dropped to 10.7; RBC 31.9. 1/9/14 his HGB dropped to 10.3; RBC to 2.98, the lowest ever recorded for him. Through all of this, his platelets have remained relatively stable, 234 - 222. We checked with all our docs about whether Brilinta was safe for him. There is absolutely nothing in any information relative to the effect Brilinta would have for anyone with some kind of anemia problem! How can that be when this is a drug manipulating the blood??? We are checking for any other cause for this drop in his blood, including any internal bleeding. But he shows no sign for any of these. We will have one more blood test in March. If it is negative again, a bone marrow biopsy will be done to make sure it is not the MDS becoming active again. But why was there no testing done for people with anemia problems? Why have I had to go through all this research trying to find the answers? The FDA is now doing some postmarketing research on Brilinta for reports of pancytopenia, neutropenia, thrombocytopenia and more. I have also talked with Brilinta's people twice now, but they have nothing to say that will address this issue. Why not??
More reviews for: Myelodysplastic syndrome, Enlarged spleen
Comments from related studies:
From this study (3 months ago):
Upon reduction of jakafi dose due to low platelet count from 20 mg to 5 mg every 12 hours patient experienced extreme pain experienced low blood pressure and rapid heartbeat and with admission to emergency was treated for shock and then diagnosed with toxic shock syndrome and treated for that. The blood and urine tests however showed ant reason for infection after 5 days. He died 40 hours after reaching the hospital. Cytokine overreaction is my belief that brought on a septic shock like syndrome.
Dave M. on Oct, 12, 2014:
Maybe patient should not have been on 20mg. Something else likely going on here with sudden reduction from 20mg to 5mg. Sudden reduction due to sudden drop in platelets. Slower dose reduction with transfusion if required would be in order.
Ann Chris on Oct, 14, 2014:
I agree. This took place 16 months ago and was done as directed by the drug rep. Since that time much more has been made known about dosage. The patient was also started on the high dose where research shows now the dose should be started low and slowly worked up. My theory is the rapid decrease in the drug caused a cytokine reaction causing system shock.
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