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Review: could Myelodysplastic syndrome cause Enlarged spleen (Splenomegaly)?

We study 11,727 people who have Myelodysplastic syndrome from FDA and social media. Among them, 103 have Enlarged spleen (Splenomegaly). Find out below who they are, other conditions they have and drugs they take.

Get connected: join a mobile support group for people who have Myelodysplastic syndrome and Enlarged spleen >>>

Myelodysplastic syndrome

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged) (latest reports from 44,278 patients)

Enlarged spleen

Enlarged spleen (enlargement of spleen) (latest reports from 39,319 patients) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, multiple sclerosis, hepatitis c.

On Sep, 15, 2014: 11,727 people who have myelodysplastic syndrome are studied. Among them, 103 (0.88%) have Enlarged Spleen.

Trend of Enlarged spleen in myelodysplastic syndrome reports

Gender of people who have myelodysplastic syndrome and experienced Enlarged spleen * :

FemaleMale
Enlarged spleen36.36%63.64%

Age of people who have myelodysplastic syndrome and experienced Enlarged spleen * :

0-12-910-1920-2930-3940-4950-5960+
Enlarged spleen1.94%0.00%0.97%0.00%0.00%0.97%15.53%81.55%

Severity of the symptom * :

n/a

Top co-existing conditions for these people * :

  1. Iron overload (8 people, 7.77%)
  2. Pain (6 people, 5.83%)
  3. Hypertension (5 people, 4.85%)
  4. Idiopathic thrombocytopenic purpura (5 people, 4.85%)
  5. Hyperuricaemia (3 people, 2.91%)
  6. Prophylaxis (3 people, 2.91%)
  7. Dyspepsia (3 people, 2.91%)
  8. Clostridial infection (3 people, 2.91%)
  9. Diarrhoea (3 people, 2.91%)
  10. Hypokalaemia (3 people, 2.91%)

Most common drugs used by these people * :

  1. Exjade (41 people, 39.81%)
  2. Revlimid (28 people, 27.18%)
  3. Neupogen (21 people, 20.39%)
  4. Thalomid (16 people, 15.53%)
  5. Aranesp (15 people, 14.56%)
  6. Allopurinol (14 people, 13.59%)
  7. Aspirin (14 people, 13.59%)
  8. Lasix (13 people, 12.62%)
  9. Acyclovir (11 people, 10.68%)
  10. Hydrea (11 people, 10.68%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Myelodysplastic Syndrome and Enlarged Spleen?

Get connected! Join a mobile support group:
- support group for people who have Enlarged Spleen and Myelodysplastic syndrome
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- support group for people who have Enlarged Spleen

Comments from related studies:

  • From this study (23 hours ago):

  • Upon reduction of jakafi dose due to low platelet count from 20 mg to 5 mg every 12 hours patient experienced extreme pain experienced low blood pressure and rapid heartbeat and with admission to emergency was treated for shock and then diagnosed with toxic shock syndrome and treated for that. The blood and urine tests however showed ant reason for infection after 5 days. He died 40 hours after reaching the hospital. Cytokine overreaction is my belief that brought on a septic shock like syndrome.

    Reply

    Dave M. on Oct, 12, 2014:

    Maybe patient should not have been on 20mg. Something else likely going on here with sudden reduction from 20mg to 5mg. Sudden reduction due to sudden drop in platelets. Slower dose reduction with transfusion if required would be in order.

    Reply

  • From this study (2 months ago):

  • My spleen became enlarged within 3 weeks after starting xarelto for pulmonary embolisms and my spleen hurts daily all the way to my shoulder.

    Reply

  • From this study (2 months ago):

  • Ive been taking warfarin for 7 years now.I have to be on it for my lifetime because Im at high risk for blood clots, pe, heartattack and stroke without taking warfarin.I also have to take it due to previous blood clots and previous PE.Also, because I have mthfr gene mutation, factor V Leiden and protein c deficiency.

    Reply

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You may be interested at these reviews (what is this?):

  • Why was this drug not tested for people with anemia problems?
    My husband has had myelodysplastic syndrome diagnosed in 2004. In 2010, his HGB went down to 10.2. RBC 3.00. He was right next to treatment when the HGB went to 10. For some unknown reason, his blood counts improved. By June 2013, his HGB was 11.9, RBC 33.9 8/3/13 he was found to have a 75% bl ...

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