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Review: could Myelodysplastic syndrome cause Enlarged spleen?

Summary: Enlarged spleen could be caused by Myelodysplastic syndrome, especially for people who are male, 60+ old, also have Iron overload, and take Exjade.

We study 11,722 people who have Myelodysplastic syndrome from FDA and social media. Among them, 103 have Enlarged spleen (Splenomegaly). Find out below who they are, other conditions they have and drugs they take.

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Enlarged spleen

Enlarged spleen (enlargement of spleen) (latest reports from 38,932 patients) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, multiple sclerosis, hepatitis c.

On Apr, 8, 2014: 11,722 people who have myelodysplastic syndrome are studied. Among them, 103 (0.88%) have Enlarged Spleen. They amount to 0.27% of all the 38,836 people who have Enlarged Spleen on eHealthMe.

Trend of Enlarged spleen in myelodysplastic syndrome reports

Gender of people who have myelodysplastic syndrome and experienced Enlarged spleen * :

Enlarged spleen36.36%63.64%

Age of people who have myelodysplastic syndrome and experienced Enlarged spleen * :

Enlarged spleen1.94%0.00%0.97%0.00%0.00%0.97%15.53%81.55%

Severity of the symptom * :


Top co-existing conditions for these people * :

  1. Iron overload (8 people, 7.77%)
  2. Pain (6 people, 5.83%)
  3. Idiopathic thrombocytopenic purpura (5 people, 4.85%)
  4. Hypertension (5 people, 4.85%)
  5. Dyspepsia (3 people, 2.91%)
  6. Hyperuricaemia (3 people, 2.91%)
  7. Oropharyngeal pain (3 people, 2.91%)
  8. Diarrhoea (3 people, 2.91%)
  9. Cardiovascular disorder (3 people, 2.91%)
  10. Clostridial infection (3 people, 2.91%)

Most common drugs used by these people * :

  1. Exjade (41 people, 39.81%)
  2. Revlimid (28 people, 27.18%)
  3. Neupogen (21 people, 20.39%)
  4. Thalomid (16 people, 15.53%)
  5. Aranesp (15 people, 14.56%)
  6. Allopurinol (14 people, 13.59%)
  7. Aspirin (14 people, 13.59%)
  8. Lasix (13 people, 12.62%)
  9. Acyclovir (11 people, 10.68%)
  10. Hydrea (11 people, 10.68%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Myelodysplastic syndrome, Enlarged spleen

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Common treatments for Myelodysplastic Syndrome and their efficacy:

Could your drug cause it?

Comments from related studies:

  • From this study (4 months ago):

  • JHeath on Dec, 18, 2013:

    Black Male, 65 years old. I started out taken Carvedilol 25 mg tablet zyd, 1 tablet 2 times a day. I developed a enlarge spleen, and I cut my dosage down to half a tablet once a day. I'm also taken 2 other blood pressure pills and a baby asprine.


  • From this study (8 months ago):

  • Enlarged Spleen, uncomfortable feeling in the spleen area, goes away when I sleep, and it doesn't hurt or feel uncomfortable all day long, just sporadic pain.


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Related condition

- Myelodysplastic syndrome (11,699 reports)


Related symptom

- Enlarged Spleen


Related drugs

- Vidaza



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