Review: taking Aleve and Levothyroxine thyroid together


Summary

Drug interactions are reported among people who take Aleve and Levothyroxine thyroid together. This review analyzes the effectiveness and drug interactions between Aleve and Levothyroxine thyroid. It is created by eHealthMe based on reports of 6,353 people who take the same drugs from FDA and social media, and is updated regularly.

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Aleve

Aleve has active ingredients of naproxen sodium. It is often used in arthritis. (latest outcomes from Aleve 37,838 users)

Levothyroxine Thyroid

Levothyroxine thyroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Levothyroxine thyroid 750 users)

On Sep, 17, 2016

6,353 people who take Aleve, Levothyroxine Thyroid are studied.


Number of reports submitted per year:

Aleve and Levothyroxine thyroid drug interactions.

Drug effectiveness over time:

Aleve:
  • < 1 month: 6.0% - (1 of 15 people)
  • 1 - 6 months: 13.0% - (3 of 22 people)
  • 6 - 12 months: 14.0% - (1 of 7 people)
  • 1 - 2 years: 33.0% - (4 of 12 people)
  • 2 - 5 years: 43.0% - (10 of 23 people)
  • 5 - 10 years: 27.0% - (5 of 18 people)
  • 10+ years: 30.0% - (4 of 13 people)
  • not specified: 0.0% - (0 of 2 people)
Levothyroxine Thyroid:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 70.0% - (12 of 17 people)
  • 2 - 5 years: 50.0% - (11 of 22 people)
  • 5 - 10 years: 59.0% - (16 of 27 people)
  • 10+ years: 68.0% - (22 of 32 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Aleve:
  • female: 24.0% - (25 of 102 people)
  • male: 30.0% - (3 of 10 people)
Levothyroxine Thyroid:
  • female: 58.0% - (58 of 100 people)
  • male: 80.0% - (8 of 10 people)

Drug effectiveness by age:

Aleve:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 5.0% - (1 of 17 people)
  • 40-49: 33.0% - (8 of 24 people)
  • 50-59: 22.0% - (7 of 31 people)
  • 60+: 27.0% - (10 of 37 people)
Levothyroxine Thyroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (3 of 3 people)
  • 30-39: 73.0% - (11 of 15 people)
  • 40-49: 60.0% - (15 of 25 people)
  • 50-59: 51.0% - (17 of 33 people)
  • 60+: 58.0% - (20 of 34 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • nausea
  • diarrhoea
  • drug ineffective
  • pruritus
  • vision blurred
  • abdominal pain
  • dizziness
  • pain
  • vomiting
1 - 6 months:
  • anxiety
  • pain
  • diarrhoea
  • fatigue
  • contusion
  • depression
  • osteonecrosis
  • arthropathy
  • emotional distress
  • gastrooesophageal reflux disease
6 - 12 months:
  • renal failure acute
  • atrial fibrillation
  • death
  • diabetes mellitus
  • vasculitis
  • diarrhoea
  • headache
  • anaemia
  • depression
  • nausea
1 - 2 years:
  • pain
  • pain in extremity
  • weight increased
  • anaemia
  • arrhythmia
  • cerebral haemorrhage
  • gastrointestinal haemorrhage
  • migraine
  • multiple injuries
  • pulmonary hypertension
2 - 5 years:
  • intervertebral disc protrusion
  • pain in extremity
  • arthralgia
  • dyspnoea
  • back pain
  • bladder disorder
  • blood cholesterol
  • dizziness
  • osteomyelitis
  • abdominal pain upper
5 - 10 years:
  • anxiety
  • deep vein thrombosis
  • depression
  • pain
  • pulmonary embolism
  • gouty arthritis
  • oedema peripheral
  • pain in extremity
  • gallbladder disorder
  • cholecystitis chronic
10+ years:
  • haemoglobin decreased
  • gastric ulcer
  • upper gastrointestinal haemorrhage
  • dizziness
  • haematemesis
  • malaise
  • pain
  • chronic fatigue syndrome
  • deep vein thrombosis
  • depression
not specified:
  • pain
  • nausea
  • fatigue
  • drug ineffective
  • arthralgia
  • pain in extremity
  • dyspnoea
  • headache
  • dizziness
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • drug ineffective
  • arthralgia
  • headache
  • pain in extremity
  • dizziness
  • dyspnoea
  • back pain
male:
  • pain
  • nausea
  • fatigue
  • dyspnoea
  • arthralgia
  • injury
  • chest pain
  • diarrhoea
  • anxiety
  • asthenia

Most common drug interactions by age *:

2-9:
  • antibody test positive
  • eye disorder
  • haemolytic anaemia
  • hypersensitivity
  • immune system disorder
  • lung disorder
  • respiratory tract infection
10-19:
  • headache
  • vomiting
  • pyrexia
  • nausea
  • chills
  • gastric disorder
  • abdominal pain upper
  • pelvic pain
  • rectal haemorrhage
  • abdominal pain
20-29:
  • pain
  • injury
  • pulmonary embolism
  • cholecystitis chronic
  • abdominal pain
  • anxiety
  • gallbladder disorder
  • nausea
  • emotional distress
  • deep vein thrombosis
30-39:
  • pain
  • fatigue
  • nausea
  • arthralgia
  • anxiety
  • pulmonary embolism
  • injury
  • headache
  • abdominal pain
  • diarrhoea
40-49:
  • nausea
  • pain
  • dyspnoea
  • fatigue
  • oedema peripheral
  • arthralgia
  • vomiting
  • pain in extremity
  • anxiety
  • back pain
50-59:
  • nausea
  • arthralgia
  • fatigue
  • headache
  • pain
  • drug ineffective
  • pain in extremity
  • back pain
  • vomiting
  • dyspnoea
60+:
  • nausea
  • drug ineffective
  • pain
  • fatigue
  • dizziness
  • dyspnoea
  • pain in extremity
  • arthralgia
  • asthenia
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Aleve (naproxen sodium) is often used to treat arthritis. Levothyroxine thyroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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