Review: taking Allopurinol and Colcrys together


Summary

Drug interactions are reported among people who take Allopurinol and Colcrys together. This review analyzes the effectiveness and drug interactions between Allopurinol and Colcrys. It is created by eHealthMe based on reports of 509 people who take the same drugs from FDA and social media, and is updated regularly.

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Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 50,176 users)

Colcrys

Colcrys has active ingredients of colchicine. It is often used in gout. (latest outcomes from Colcrys 555 users)

On Jul, 20, 2016

509 people who take Allopurinol, Colcrys are studied.


Number of reports submitted per year:

Allopurinol and Colcrys drug interactions.

Drug effectiveness over time:

Allopurinol:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 21.0% - (3 of 14 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 14.0% - (1 of 7 people)
  • 2 - 5 years: 33.0% - (4 of 12 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 50.0% - (7 of 14 people)
  • not specified: 66.0% - (2 of 3 people)
Colcrys:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 16.0% - (2 of 12 people)
  • 6 - 12 months: 33.0% - (3 of 9 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 15.0% - (2 of 13 people)
  • 5 - 10 years: 83.0% - (5 of 6 people)
  • 10+ years: 77.0% - (7 of 9 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Allopurinol:
  • female: 20.0% - (1 of 5 people)
  • male: 33.0% - (19 of 57 people)
Colcrys:
  • female: 25.0% - (1 of 4 people)
  • male: 38.0% - (22 of 57 people)

Drug effectiveness by age:

Allopurinol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 18.0% - (3 of 16 people)
  • 60+: 42.0% - (14 of 33 people)
Colcrys:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 66.0% - (2 of 3 people)
  • 40-49: 42.0% - (3 of 7 people)
  • 50-59: 18.0% - (3 of 16 people)
  • 60+: 42.0% - (14 of 33 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • cellulitis
  • nausea
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • asthenia
  • blood lactate dehydrogenase increased
  • chills
  • coma
  • decreased appetite
1 - 6 months:
  • diarrhoea
  • pyrexia
  • urticaria
  • back pain
  • colitis
  • constipation
  • dizziness
  • dyspepsia
  • hepatic steatosis
  • hyperkalaemia
6 - 12 months:
  • arrhythmia
  • blood cholesterol abnormal
  • blood pressure abnormal
  • cardiomyopathy
  • cholelithiasis
  • dementia alzheimer's type
  • gallbladder disorder
  • gallbladder enlargement
  • gout
  • hepatic enzyme increased
1 - 2 years:
  • drug ineffective
  • prostate cancer
  • prostatic specific antigen increased
  • psychosis aggravated
  • erectile dysfunction
  • gout
  • insomnia
  • stomach pain
  • tinnitus
2 - 5 years:
  • acid reflux
  • allergies
  • gouty arthritis
  • high blood pressure
  • polyarthralgia
  • thrombocytopenia
  • headache
  • pain - ankle
  • ringing in the ears
5 - 10 years:
  • chest pain
  • delayed urination
  • diarrhoea
  • muscle twitching
  • nausea
  • swelling of the ankles - feet - legs
  • gout
  • erectile dysfunction
  • lymphoedema
10+ years:
  • rectal bleeding
  • chest pain
  • delayed urination
  • muscle twitching
  • nausea
  • swelling of the ankles - feet - legs
  • blood pressure decreased
  • hot flashes
  • low blood pressure
  • brittle nails
not specified:
  • gout
  • nausea
  • diarrhoea
  • pyrexia
  • weight decreased
  • drug ineffective
  • cardiac failure congestive
  • vomiting
  • blood creatinine increased
  • fatigue

Most common drug interactions by gender *:

female:
  • gout
  • diarrhoea
  • malaise
  • nausea
  • vomiting
  • hypertension
  • weight decreased
  • oedema peripheral
  • constipation
  • blood cholesterol increased
male:
  • gout
  • pyrexia
  • nausea
  • drug ineffective
  • blood creatinine increased
  • diarrhoea
  • cardiac arrest
  • oedema peripheral
  • weight decreased
  • cardiac failure congestive

Most common drug interactions by age *:

20-29:
  • haemoglobin decreased
  • aplastic anaemia
  • haematocrit decreased
  • muscle weakness
  • nocardiosis
  • pneumocystis carinii infection
  • pulmonary haemorrhage
  • pyrexia
  • thrombocytopenia
  • toxoplasmosis
30-39:
  • hypertensive crisis
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood lactate dehydrogenase increased
  • chills
  • decreased appetite
  • hyperhidrosis
  • pain
  • pallor
  • peripheral coldness
40-49:
  • gout
  • erythema multiforme
  • pyrexia
  • cough
  • liver function tests nos abnormal
  • nausea
  • cellulitis
  • diarrhoea
  • abdominal pain upper
  • aortic valve replacement
50-59:
  • nausea
  • oedema peripheral
  • pruritus
  • pyrexia
  • drug hypersensitivity
  • hepatic steatosis
  • hyperkalaemia
  • malaise
  • weight decreased
  • colitis
60+:
  • gout
  • diarrhoea
  • nausea
  • drug ineffective
  • cardiac failure congestive
  • asthenia
  • blood creatinine increased
  • fatigue
  • cardiac arrest
  • blood pressure increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Allopurinol (allopurinol) is often used to treat gout. Colcrys (colchicine) is often used to treat gout. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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