Review: taking Allopurinol and Ibuprofen together


Summary

Drug interactions are reported among people who take Allopurinol and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Allopurinol and Ibuprofen. It is created by eHealthMe based on reports of 1,057 people who take the same drugs from FDA and social media, and is updated regularly.

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Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 50,176 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 60,808 users)

On Jul, 20, 2016

1,057 people who take Allopurinol, Ibuprofen are studied.


Number of reports submitted per year:

Allopurinol and Ibuprofen drug interactions.

Drug effectiveness over time:

Allopurinol:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 85.0% - (6 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Ibuprofen:
  • < 1 month: 0.0% - (0 of 7 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Allopurinol:
  • female: 20.0% - (2 of 10 people)
  • male: 75.0% - (9 of 12 people)
Ibuprofen:
  • female: 0.0% - (0 of 9 people)
  • male: 50.0% - (6 of 12 people)

Drug effectiveness by age:

Allopurinol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 4 people)
  • 50-59: 40.0% - (2 of 5 people)
  • 60+: 72.0% - (8 of 11 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 5 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 50.0% - (5 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • blood uric acid increased
  • hyperuricaemia
  • asthenia
  • renal failure acute
  • gastrointestinal haemorrhage
  • arthralgia
  • back pain
  • dyspnoea
  • erythema
1 - 6 months:
  • blood uric acid increased
  • hyperuricaemia
  • weight decreased
  • diarrhoea
  • back pain
  • colitis
  • constipation
  • dyspepsia
  • hepatic steatosis
  • hyperkalaemia
6 - 12 months:
  • gynaecomastia
  • renal failure acute
  • anxiety aggravated
  • depression
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • haemarthrosis
  • headache
  • vision blurred
  • weight gain - unintentional
1 - 2 years:
  • aggression
  • autoimmune thrombocytopenia
  • blood chloride decreased
  • cholecystitis acute
  • constipation
  • deafness
  • diplopia
  • disseminated intravascular coagulation
  • dizziness
  • dyspepsia
2 - 5 years:
  • atrial fibrillation
  • decreased appetite
  • diarrhoea
  • hepatitis acute
  • renal failure acute
  • urinary tract infection
  • weight decreased
  • anxiety aggravated
  • blood creatinine increased
  • blood urea increased
5 - 10 years:
  • aggression
  • amnesia
  • anxiety
  • asthenia
  • c-reactive protein increased
  • cardiac arrest
  • dehydration
  • depression
  • diarrhoea
  • gastroenteritis rotavirus
10+ years:
  • c-reactive protein increased
  • dehydration
  • diarrhoea
  • gastroenteritis rotavirus
  • hypokalaemia
  • hyponatraemia
  • pneumonia
  • renal failure
  • syncope
  • arthritis
not specified:
  • pain
  • back pain
  • anaemia
  • nausea
  • anxiety
  • dyspnoea
  • fatigue
  • dizziness
  • abdominal pain
  • arthralgia

Most common drug interactions by gender *:

female:
  • nausea
  • abdominal pain
  • pain
  • back pain
  • anaemia
  • anxiety
  • dyspnoea
  • fatigue
  • malaise
  • oedema peripheral
male:
  • pain
  • anaemia
  • anxiety
  • dizziness
  • back pain
  • dyspnoea
  • pyrexia
  • arthralgia
  • asthenia
  • nausea

Most common drug interactions by age *:

0-1:
  • hyperkalaemia
  • malaise
  • renal failure
20-29:
  • deep vein thrombosis
  • dyspnoea
  • nausea
  • anaemia
  • asthenia
  • conjunctivitis viral
  • insomnia
  • urinary tract infection
  • gastritis
  • herpes zoster
30-39:
  • hypertension
  • fatigue
  • myocardial infarction
  • night sweats
  • cardiac arrest
  • dizziness
  • lymphadenopathy
  • myalgia
  • abdominal pain
  • anaemia
40-49:
  • anxiety
  • pain
  • pyrexia
  • decreased appetite
  • oedema peripheral
  • bone disorder
  • headache
  • back pain
  • bone pain
  • dizziness
50-59:
  • anxiety
  • pain
  • back pain
  • nausea
  • dizziness
  • anaemia
  • weight decreased
  • emotional distress
  • impaired healing
  • arthralgia
60+:
  • back pain
  • dyspnoea
  • fatigue
  • nausea
  • pain
  • abdominal pain
  • asthenia
  • renal failure acute
  • arthralgia
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Allopurinol (allopurinol) is often used to treat gout. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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