Review: taking Allopurinol and Ibuprofen together


Summary

Drug interactions are reported among people who take Allopurinol and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Allopurinol and Ibuprofen. It is created by eHealthMe based on reports of 1,901 people who take the same drugs from FDA and social media, and is updated regularly.

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Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 75,375 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 92,739 users)

On Sep, 16, 2016

1,901 people who take Allopurinol, Ibuprofen are studied.


Number of reports submitted per year:

Allopurinol and Ibuprofen drug interactions.

Drug effectiveness over time:

Allopurinol:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 83.0% - (5 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Ibuprofen:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Allopurinol:
  • female: 28.0% - (2 of 7 people)
  • male: 72.0% - (8 of 11 people)
Ibuprofen:
  • female: 0.0% - (0 of 6 people)
  • male: 54.0% - (6 of 11 people)

Drug effectiveness by age:

Allopurinol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 40.0% - (2 of 5 people)
  • 60+: 70.0% - (7 of 10 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 55.0% - (5 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • renal failure acute
  • myositis
  • diarrhoea
  • asthenia
  • vomiting
  • dyspnoea
  • nausea
  • back pain
  • blood uric acid increased
1 - 6 months:
  • blood uric acid increased
  • hyperuricaemia
  • diarrhoea
  • general physical health deterioration
  • gastrointestinal haemorrhage
  • pyrexia
  • dyspepsia
  • malaise
  • nausea
  • vomiting
6 - 12 months:
  • gynaecomastia
  • fatigue
  • peripheral swelling
  • renal failure acute
  • abdominal pain upper
  • dyspepsia
  • gastrointestinal haemorrhage
  • general physical health deterioration
  • malignant melanoma in situ
  • nervousness
1 - 2 years:
  • dyspnoea
  • deep vein thrombosis
  • acute respiratory failure
  • body temperature increased
  • cough
  • dementia alzheimer's type
  • dyspepsia
  • eye swelling
  • fatigue
  • lung infiltration
2 - 5 years:
  • renal impairment
  • tubulointerstitial nephritis
  • haematuria
  • abdominal discomfort
  • arthralgia
  • atrial fibrillation
  • chest pain
  • decreased appetite
  • diarrhoea
  • dizziness
5 - 10 years:
  • anaemia
  • pancytopenia
  • renal impairment
  • aggression
  • amnesia
  • anxiety
  • asthenia
  • c-reactive protein increased
  • cardiac arrest
  • dehydration
10+ years:
  • gastrointestinal haemorrhage
  • renal failure
  • c-reactive protein increased
  • dehydration
  • diarrhoea
  • gastroenteritis rotavirus
  • hypokalaemia
  • hyponatraemia
  • pneumonia
  • syncope
not specified:
  • nausea
  • pain
  • anaemia
  • back pain
  • fatigue
  • dyspnoea
  • dizziness
  • anxiety
  • asthenia
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • back pain
  • fatigue
  • abdominal pain
  • anaemia
  • anxiety
  • vomiting
  • dyspnoea
  • diarrhoea
male:
  • anaemia
  • nausea
  • pain
  • dyspnoea
  • dizziness
  • fatigue
  • asthenia
  • pyrexia
  • back pain
  • anxiety

Most common drug interactions by age *:

0-1:
  • hepatic enzyme increased
  • hyperkalaemia
  • hypertension
  • malaise
  • renal failure
2-9:
  • anaphylactic reaction
  • deafness neurosensory
  • delirium
  • dyspnoea
  • lip swelling
  • macrocytosis
10-19:
  • headache
  • hypercalcaemia
  • hyperglycaemia
  • hypoalbuminaemia
  • hypocalcaemia
  • hypokalaemia
  • hyponatraemia
  • nausea
  • urinary retention
  • alanine aminotransferase increased
20-29:
  • anaemia
  • deep vein thrombosis
  • insomnia
  • dyspnoea
  • asthenia
  • gastritis
  • nausea
  • conjunctivitis viral
  • urinary tract infection
  • pneumothorax
30-39:
  • dizziness
  • hypertension
  • night sweats
  • fatigue
  • lymphadenopathy
  • nausea
  • myocardial infarction
  • pain
  • anaemia
  • cardiac arrest
40-49:
  • anxiety
  • pain
  • oedema peripheral
  • pyrexia
  • headache
  • dizziness
  • bone disorder
  • decreased appetite
  • back pain
  • diarrhoea
50-59:
  • anxiety
  • pain
  • dizziness
  • nausea
  • back pain
  • hypotension
  • hypertension
  • pyrexia
  • anaemia
  • weight decreased
60+:
  • nausea
  • fatigue
  • dyspnoea
  • anaemia
  • back pain
  • pain
  • asthenia
  • vomiting
  • diarrhoea
  • renal failure acute

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Allopurinol (allopurinol) is often used to treat gout. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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